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Showing 3,4213,440 of 20,252 grants

Completed NON SBIR/STTR CONTRACTS
NCI RESEARCH LEVEL NUTRIENT AND FOOD GROUP DATABASE
NATIONAL CANCER INSTITUTE University of Minnesota United States 2023 – 2024

INITIAL AWARD TO PROVIDE THE NCI WITH THE RESEARCH LEVEL NUTRIENT AND FOOD GROUP DATABASE TO PROVIDE ITS EXTENSIVE LIST OF NUTRIENTS AND FOOD COMPONENTS ON ITS PUBLIC USE FOOD FREQ...

$290K
USD
Active NON-SBIR/STTR RPGS
The role of regulation and subcellular localization of GTP biosynthesis in melanoma invasion and metastasis
NATIONAL CANCER INSTITUTE Duke University United States 2023 – 2028

Metastatic melanoma is the most aggressive type of skin cancer with no treatment. Acquisition of invasive phenotypes is a critical event driving progression from primary to metasta...

$4.8M
USD
Active TRAINING, INDIVIDUAL
Low Dose Computed Tomography (LDCT) Eligibility and Outcome differences between Sexual and Gender Minorities and their Sexual and Gender Majority Counterparts
NATIONAL CANCER INSTITUTE University of Michigan At Ann Arbor United States 2023 – 2026

Project Summary Cigarette smoking accounts for 1 in 5 preventable deaths in the United States. Sexual and gender minorities (SGM) are at higher risk of cigarette smoking and tobacc...

$474.3K
USD
Active RESEARCH CENTERS
Washington University SPORE in Pancreatic Cancer
NATIONAL CANCER INSTITUTE Washington University United States 2023 – 2028

PROJECT SUMMARY The Washington University Specialized Program of Research Excellence (SPORE) in Pancreatic Cancer is a highly translational cancer research program focused entirely...

$20.65M
USD
Active RESEARCH CENTERS
Core A: Administrative Core
NATIONAL CANCER INSTITUTE Washington University United States 2023 – 2028

PROJECT SUMMARY The Administrative Core aims to provide executive oversight and administrative support for all SPORE in Pancreatic Cancer projects and cores. The Administrative Cor...

Active RESEARCH CENTERS
Project 1: Employing CD11b-Agonists to Render PDAC Responsive to Immunotherapy
NATIONAL CANCER INSTITUTE Washington University United States 2023 – 2028

PROJECT SUMMARY The potential of checkpoint immunotherapy to combat cancer has been established in several cancer types. However, in pancreatic ductal adenocarcinoma (PDAC), checkp...

Active RESEARCH CENTERS
Project 2: Mechanisms of Resistance to Neoantigen Vaccines in PDAC
NATIONAL CANCER INSTITUTE Washington University United States 2023 – 2028

ABSTRACT We have made important contributions to the immunobiology of cancer neoantigens, and have developed a robust, publically available, and frequently downloaded suite of soft...

Active RESEARCH CENTERS
Project 3: Targeting Stress-induced MK2 as Novel Strategy in Pancreatic Cancer
NATIONAL CANCER INSTITUTE Washington University United States 2023 – 2028

PROJECT SUMMARY We propose a phase 1 clinical trial to test the safety and preliminary efficacy of a new therapeutic strategy that aims at augmenting the efficacy of standard chemo...

Active RESEARCH CENTERS
Core B: Biospecimen Core
NATIONAL CANCER INSTITUTE Washington University United States 2023 – 2028

PROJECT SUMMARY The controlled collection and processing of clinical specimens from patients with pancreatic ductal adenocarcinoma (PDAC) is a critical activity for an efficient an...

Active RESEARCH CENTERS
Core C: Biostatistical and Bioinformatics Core
NATIONAL CANCER INSTITUTE Washington University United States 2023 – 2028

PROJECT SUMMARY The Biostatistics and Bioinformatics Core (Core C) facility will provide study design, pipeline development, data management, and computational support for all SPOR...

Active RESEARCH CENTERS
Developmental Research Program
NATIONAL CANCER INSTITUTE Washington University United States 2023 – 2028

PROJECT SUMMARY The goal of the SPORE in Pancreatic Cancer Developmental Research Program (DRP) is to recruit and support developmental research projects in pancreatic cancer for f...

Active RESEARCH CENTERS
Career Enhancement Program
NATIONAL CANCER INSTITUTE Washington University United States 2023 – 2028

PROJECT SUMMARY The SPORE in Pancreatic Cancer Career Enhancement Program (CEP) aims to recruit and support new independent investigators in translational pancreatic cancer researc...

Active NON-SBIR/STTR RPGS
Strategies for Optimizing a Mailed FIT Program in Appalachia
NATIONAL CANCER INSTITUTE Ohio State University United States 2023 – 2028

PROJECT SUMMARY Colorectal cancer (CRC) is the third most common cancer among both men and women and the second leading cause of cancer deaths in the United States (US). CRC screen...

$5.84M
USD
Completed SBIR/STTR CONTRACTS
SBIR TOPIC 417: QUANTITATIVE IMAGING SOFTWARE TOOLS FOR CANCER DIAGNOSIS AND TREATMENT PLANNING
NATIONAL CANCER INSTITUTE Neuralrad Llc United States 2023 – 2025

With brain metastases (BMs) incidences rapidly increasing due to improved systemic treatment and cancer patients, survival, the BMs management strategies have evolved substantially...

$19.9M
USD
Active TRAINING, INDIVIDUAL
Low Dose Computed Tomography (LDCT) Eligibility and Outcome differences between Sexual and Gender Minorities and their Sexual and Gender Majority Counterparts
NATIONAL CANCER INSTITUTE University of Michigan At Ann Arbor United States 2023 – 2026

Project Summary Cigarette smoking accounts for 1 in 5 preventable deaths in the United States. Sexual and gender minorities (SGM) are at higher risk of cigarette smoking and tobacc...

$414.8K
USD
Active NON-SBIR/STTR RPGS
Strategies for Optimizing a Mailed FIT Program in Appalachia
NATIONAL CANCER INSTITUTE Ohio State University United States 2023 – 2028

PROJECT SUMMARY Colorectal cancer (CRC) is the third most common cancer among both men and women and the second leading cause of cancer deaths in the United States (US). CRC screen...

$4.68M
USD
Active RESEARCH CENTERS
Washington University SPORE in Pancreatic Cancer
NATIONAL CANCER INSTITUTE Washington University United States 2023 – 2028

PROJECT SUMMARY The Washington University Specialized Program of Research Excellence (SPORE) in Pancreatic Cancer is a highly translational cancer research program focused entirely...

$20.91M
USD
Active RESEARCH CENTERS
Core A: Administrative Core
NATIONAL CANCER INSTITUTE Washington University United States 2023 – 2028

PROJECT SUMMARY The Administrative Core aims to provide executive oversight and administrative support for all SPORE in Pancreatic Cancer projects and cores. The Administrative Cor...

Active RESEARCH CENTERS
Project 1: Employing CD11b-Agonists to Render PDAC Responsive to Immunotherapy
NATIONAL CANCER INSTITUTE Washington University United States 2023 – 2028

PROJECT SUMMARY The potential of checkpoint immunotherapy to combat cancer has been established in several cancer types. However, in pancreatic ductal adenocarcinoma (PDAC), checkp...

Active RESEARCH CENTERS
Project 2: Mechanisms of Resistance to Neoantigen Vaccines in PDAC
NATIONAL CANCER INSTITUTE Washington University United States 2023 – 2028

ABSTRACT We have made important contributions to the immunobiology of cancer neoantigens, and have developed a robust, publically available, and frequently downloaded suite of soft...