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Showing 2,7812,800 of 20,252 grants

Active RESEARCH CENTERS
Full Project 2: The Intersection of Telehealth and Health Disparities in At-Risk Older Patients with Cancer
NATIONAL CANCER INSTITUTE University of California, San Diego United States 2023 – 2028

PROJECT SUMMARY/ ABSTRACT – PROJECT 2 Telehealth utilization increased rapidly across the US healthcare system in response to the COVID-19 pandemic. As we emerge from the pandemic,...

Active OTHER RESEARCH-RELATED
Baltimore CASCADE Study Site (BaCSS Project)
NATIONAL CANCER INSTITUTE University of Maryland Baltimore United States 2023 – 2027

Baltimore CASCADE Study Site (BaCSS Project) Project summary Women living with HIV (WLWH) have a higher risk of cervical cancer because of incomplete immune reconstitution and high...

$3.09M
USD
Active RESEARCH CENTERS
Pilot Project 1: Creating Bridges to Reproductive Health Care for Rural Adolescent and Young Adult Cancer Survivors
NATIONAL CANCER INSTITUTE University of California, San Diego United States 2023 – 2028

PROJECT SUMMARY/ ABSTRACT – PILOT PROJECT Reproductive health care in cancer patients is an unmet need in Imperial County, a medically underserved, rural region of the Cancer Resea...

Active RESEARCH CENTERS
Planning and Evaluation Core
NATIONAL CANCER INSTITUTE University of California, San Diego United States 2023 – 2028

PROJECT SUMMARY/ ABSTRACT – PLANNING AND EVALUATION CORE The Planning and Evaluation (P&E) Core of the Cancer Research and Education to Advance HealTh Equity (CREATE) Partnersh...

Active RESEARCH CENTERS
Administrative Core
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2023 – 2028

ADMINISTRATIVE CORE SUMMARY The Administrative Core remains a central component of the Moffitt CSBC. It has oversight of the disbursal of funds to the Projects and Cores. It is the...

Active RESEARCH CENTERS
Project 1: Delta immune Ecology of NSCLC
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2023 – 2028

Summary – Project 1 Project 1 will study the ∆-Ecology of tumor-immune interactions in NSCLC, with a focus on KRAS-mutant cancers. Immunotherapy has demonstrated response rates of...

Active RESEARCH CENTERS
Project 2: Delta Stromal Ecology of NSCLC
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2023 – 2028

Project 2 abstract Project 2 will investigate the changes in neoplastic and stromal compartments during the acquisition of resistance to ALK and KRAS targeting therapies, with spec...

Active RESEARCH CENTERS
Outreach Core
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2023 – 2028

Summary Central to the Moffitt-CSBC Education core is an annual innovative, unique, and intense one-week interdisciplinary hands-on workshop to accelerate the training of the next...

Active RESEARCH CENTERS
Core 1: Mathematical Core
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2023 – 2028

Summary – Mathematical Modeling Core Understanding the changes in tumor ecology (“∆-Ecology”) that occur during tumor initiation, progression, and therapy requires careful study of...

Active RESEARCH CENTERS
Core 2: Ecological Core
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2023 – 2028

Summary – Ecological Core Recent advances in spatial ‘omics’ have led to an increased interest in studying and predicting emergent aggregate behavior and interactions between the t...

Active RESEARCH CENTERS
Quantitative systems biology of glioblastoma cells and their interactions with the neuronal and immunological milieu
NATIONAL CANCER INSTITUTE Massachusetts Institute of Technology United States 2023 – 2028

ABSTRACT – OVERALL The primary focus of the MIT/DFCI Center for Systems Biology of Glioblastoma is to understand the intersections between neurons, immune cells, and tumor cells in...

$19.02M
USD
Active RESEARCH CENTERS
Administrative Core
NATIONAL CANCER INSTITUTE Massachusetts Institute of Technology United States 2023 – 2028

ABSTRACT - ADMINISTRATIVE CORE The overarching framework for this MIT/DFCI Center for Systems Biology of Glioblastoma is to use systems biology to define the dynamic evolution of t...

Active RESEARCH CENTERS
The Delta Ecology of NSCLC Treatment
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2023 – 2028

Summa - Moffitt CSBC Pro osal Overview The Moffitt CSBC proposal is focused on the essential and highly dynamical interplay between cancer cell evolution and the constantly changin...

$674.8K
USD
Active NON-SBIR/STTR RPGS
Racially-associated MRI analysis and modeling for predicting aggressive prostate cancer
NATIONAL CANCER INSTITUTE University of California Los Angeles United States 2023 – 2028

PROJECT SUMMARY African American (AA) men have the highest incidence and mortality rate from prostate cancer (PCa) in the United States. Prostate multi-parametric MRI (mpMRI) is a...

$821.2K
USD
Active RESEARCH CENTERS
Impact of immune-targeting therapies on the GBM tumor immune interface
NATIONAL CANCER INSTITUTE Massachusetts Institute of Technology United States 2023 – 2028

ABSTRACT – OVERALL The primary focus of the MIT/DFCI Center for Systems Biology of Glioblastoma is to understand the intersections between neurons, immune cells, and tumor cells in...

$1.59M
USD
Active NON-SBIR/STTR RPGS
Leveraging artificial intelligence/machine learning-based technology to overcome specialized training and technology barriers for the diagnosis and prognostication of colorectal cancer in Africa
NATIONAL CANCER INSTITUTE Aga Khan University (Kenya Kenya 2023 – 2026

SUMMARY/ABSTRACT Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the second leading cause of cancer related deaths worldwide. Rates in Africa are on the ris...

$2.5M
USD
Active NON-SBIR/STTR RPGS
Biomarker Validation in Pancreatic Cystic Neoplasms
NATIONAL CANCER INSTITUTE University of California, San Diego United States 2023 – 2028

Project Summary Pancreatic cystic neoplasm (PCN) represents a common incidental finding in the population. Branch-duct intraductal papillary mucinous neoplasms (IPMN), the most com...

$8.2M
USD
Active RESEARCH CENTERS
Project 2: Deciphering the Dynamic Evolution of the Tumor-Immune Interface
NATIONAL CANCER INSTITUTE Massachusetts Institute of Technology United States 2023 – 2028

This application is being submitted in response to the Notice of Special Interest (NOSI) identified as NOT-CA24-029.Glioblastoma (GBM) is a lethal form of brain cancer with a media...

Active RESEARCH CENTERS
Administrative Core
NATIONAL CANCER INSTITUTE H. Lee Moffitt Cancer Ctr & Res Inst United States 2023 – 2028

ADMINISTRATIVE CORE SUMMARY The Administrative Core remains a central component of the Moffitt CSBC. It has oversight of the disbursal of funds to the Projects and Cores. It is the...

Active NON-SBIR/STTR RPGS
NCI Research Specialist/Clinician Scientist Award for Urologic Oncology Research
NATIONAL CANCER INSTITUTE University of California Los Angeles United States 2023 – 2028

Project Summary As a urologic oncologist, most of my peers have focused on operating as much as possible with the hope their efforts could positively effect change on an individual...

$1.15M
USD