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20,252 grants found
Showing 2,681 – 2,700 of 20,252 grants
Outreach Core
SUMMARY: OUTREACH CORE The goals of the scientific portion of this proposal are directed towards bringing personalized medicine to the clinic for glioblastoma patients through inte...
MOSAIC: Biospecimen Core
SUMMARY: BIOSPECIMEN CORE The major objective of the Biospecimen Core is to obtain, process, image, and analyze glioblastoma (GBM) patients’ biopsies for use in both Projects of ou...
MOSAIC: Data Integration and Computation Core
SUMMARY: DATA INTEGRATION AND COMPUTATION CORE A major challenge to any integrated, collaborative, multi-institutional effort is the centralized management and synthesis of shared...
Neoadjuvant immunoradiotherapy for HPV mediated oropharynx cancer
Project Summary HPV mediated oropharynx cancer (HPVOPC) is projected to increase in incidence in the United States over the next 20-years. Attempts to de-escalate nonsurgical treat...
San Diego State University Advancing Cancer Careers for ExceLlence (ACCEL)
PROJECT SUMMARY / ABSTRACT San Diego State University’s Advancing Cancer Careers for ExceLlence (ACCEL) Program, in partnership with University of California San Diego (UCSD) Moore...
Development of An Innovative TEE Technology for Mutation Detection
Abstract The objective of this project is to further develop a breakthrough Toehold-Enrichment- Extraction (TEE) technology and validate TEE-based tests for use in cancer detection...
Elucidating mechanisms of checkpoint inhibitor-induced diabetes
Abstract: This K08 proposal will expedite the principal investigator’s progress towards her goal of becoming an independent physician-scientist with a focus on increasing our under...
Towards an inclusive genomic risk classification for acute myeloid leukemia (AML)
A. PROJECT SUMMARY Acute myeloid leukemia (AML) is the most common adult acute leukemia. Molecular features such as cytogenetics and somatic mutations are essential components of r...
Molecular Mechanisms of Wnt Transport
ABSTRACT Wnts are a family of evolutionary conserved, secreted ligands that act at short range to coordinate morphogenetic movements and cell fate decisions. Secretion of Wnt and s...
B Cells and Tertiary Lymphoid Structures: Emerging Targets in Cancer Therapeutics
ABSTRACT Support is requested for a Keystone Symposia conference entitled B Cells and Tertiary Lymphoid Structures: Emerging Targets in Cancer Therapeutics, organized by Drs. Tulli...
Development of An Innovative TEE Technology for Mutation Detection
Abstract The objective of this project is to further develop a breakthrough Toehold-Enrichment- Extraction (TEE) technology and validate TEE-based tests for use in cancer detection...
Clinician Scientist Supporting NCI-funded Clinical Trials at the Medical College of Wisconsin Cancer Center
PROJECT SUMMARY This application seeks partial salary support for a clinician scientist who is a highly accomplished clinical trialist in the Cancer Center at the Medical College o...
Clinician Scientist in Leukemia
PROJECT SUMMARY / ABSTRACT This project is intended to support the applicant as a clinician-scientist in leukemia at Washington University School of Medicine / Siteman Cancer Cente...
Increasing access to cancer trials in Minnesota (InACT-MN)
PROJECT SUMMARY/ABSTRACT In collaboration with the Masonic Cancer Center of the University of Minnesota, Britt Erickson, MD, has developed a research strategy that will leverage he...
Mathematical Oncology Systems Analysis Imaging Center (MOSAIC)
SUMMARY: OVERALL: MATHEMATICAL ONCOLOGY SYSTEMS ANALYSIS IMAGING CENTER Glioblastoma (GBM), the most aggressive primary brain cancer, is amongst the most heterogeneous of cancers,...
MOSAIC: Administrative Core
SUMMARY: ADMINISTRATIVE CORE The overarching objective for the Mayo/Columbia MOSAIC CSBC is to build a conceptual framework to understand tissue state transitions that happen in gl...
MOSAIC: Targeting the Tissue State
SUMMARY: PROJECT 1: TARGETING GLIOMA TISSUE STATES Glioblastoma (GBM) displays extensive cellular heterogeneity which represents a major obstacle for effective treatment. This cell...
MOSAIC: Imaging Human Tissue State Dynamics In Vivo
SUMMARY: PROJECT 2: IMAGING THE DYNAMIC TISSUE STATE IN PATIENTS IN VIVO With a dismal median survival of 16 months, glioblastoma (GBM) is the most common malignant primary brain t...
Outreach Core
SUMMARY: OUTREACH CORE The goals of the scientific portion of this proposal are directed towards bringing personalized medicine to the clinic for glioblastoma patients through inte...
MOSAIC: Biospecimen Core
SUMMARY: BIOSPECIMEN CORE The major objective of the Biospecimen Core is to obtain, process, image, and analyze glioblastoma (GBM) patients’ biopsies for use in both Projects of ou...