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Completed RESEARCH CENTERS
Racial and social contextual factors in relation to epigenome and bladder cancer outcome
NATIONAL CANCER INSTITUTE Texas Southern University United States 2023 – 2025

CURED PILOT Project 2 Summary This proposal entails strengthening the efforts between Dan L Duncan Comprehensive Cancer Center (DLDCCC) at Baylor College of Medicine (BCM) and Texa...

Active RESEARCH CENTERS
BCM/TSU P20 Collaborative Union for Cancer Research, Education and Disparities (CURED) Collaborative Cancer Research Education Program (C-REP)
NATIONAL CANCER INSTITUTE Texas Southern University United States 2023 – 2027

CURED C-REP Summary/Abstract The Collaborative Cancer Research Education Program (C-REP) of the Baylor College of Medicine (BCM)/ Dan L Duncan Comprehensive Cancer Center (DLDCCC)...

Active RESEARCH CENTERS
1/2 Collaborative Union for Cancer Research, Education and Disparities (CURED)
NATIONAL CANCER INSTITUTE Baylor College of Medicine United States 2023 – 2027

CURED Overall Abstract Dan L Duncan Comprehensive Cancer Center (DLDCCC) at Baylor College of Medicine (BCM) and Texas Southern University (TSU) are jointly submitting a P20 applic...

$3M
USD
Active RESEARCH CENTERS
BCM-TSU CURED Administration Core (AC)
NATIONAL CANCER INSTITUTE Baylor College of Medicine United States 2023 – 2027

ABSTRACT – CURED Administrative Core Administrative Core of the proposed BCM-TSU P20 CURED program will serve as a primary administrative unit that oversees the collaborative resea...

Active RESEARCH CENTERS
Impact of race and ethnicity on outcomes in patients with hormone receptor-positive breast cancer treated with CDK4/6 inhibitors
NATIONAL CANCER INSTITUTE Baylor College of Medicine United States 2023 – 2027

Breast cancer (BC) is the most common cancer in women worldwide and is the second leading cause of cancer death in women. However, the advances in outcomes of BC patients have been...

Active OTHER RESEARCH-RELATED
Methods Training for Comparative Effectiveness Research in Cancer
NATIONAL CANCER INSTITUTE University of Tx Md Anderson Can Ctr United States 2023 – 2028

Comparative effectiveness research (CER) aims to inform healthcare decisions by providing evidence on the benefits and harms of different alternatives in cancer care. While randomi...

$3.21M
USD
Active NON-SBIR/STTR RPGS
Elucidating a novel WNT4 regulatory axis as a driver of gynecologic cancer health disparities
NATIONAL CANCER INSTITUTE University of Colorado Denver United States 2023 – 2028

PROJECT SUMMARY/ABSTRACT Gynecologic malignancies such as ovarian cancer (OvCa) are among the deadliest cancers affecting women due to therapy resistance and limited understanding...

$6.46M
USD
Active NON-SBIR/STTR RPGS
Assessing Benefits and Harms of Cannabis and Cannabinoid Use Among a Cohort of Cancer Patients Treated in Community Oncology Clinics
NATIONAL CANCER INSTITUTE Wake Forest University Health Sciences United States 2023 – 2028

SUMMARY Cancer patients suffer from a multitude of debilitating symptoms associated with cancer and cancer treatment, many of which are not relieved with prescription medications....

$6.7M
USD
Active NON-SBIR/STTR RPGS
A novel molecularly targeted theranostic approach via the alphavbeta6 integrin for the detection and treatment of metastatic cancers
NATIONAL CANCER INSTITUTE University of California At Davis United States 2023 – 2028

PROJECT SUMMARY/ABSTRACT We propose to evaluate a novel αvβ6 integrin molecularly targeted theranostic approach for the detection and treatment of metastatic cancers. The αvβ6 inte...

$6.65M
USD
Active RESEARCH CENTERS
BCM/TSU P20 Collaborative Union for Cancer Research, Education and Disparities (CURED) Collaborative Cancer Research Education Program (C-REP)
NATIONAL CANCER INSTITUTE Texas Southern University United States 2023 – 2027

CURED C-REP Summary/Abstract The Collaborative Cancer Research Education Program (C-REP) of the Baylor College of Medicine (BCM)/ Dan L Duncan Comprehensive Cancer Center (DLDCCC)...

Active NON-SBIR/STTR RPGS
Engineering Exosome for Pancreatic Cancer Targeting Therapies
NATIONAL CANCER INSTITUTE University of Toledo Health Sci Campus United States 2023 – 2028

Pancreatic Ductal Adenocarcinoma (PDAC) is one of the deadliest cancers and ranks fourth in cancer- related deaths in the United States. Therapies for pancreatic cancer are largely...

$4.98M
USD
Active RESEARCH CENTERS
BCM-TSU CURED Administration Core (AC)
NATIONAL CANCER INSTITUTE Baylor College of Medicine United States 2023 – 2027

ABSTRACT – CURED Administrative Core Administrative Core of the proposed BCM-TSU P20 CURED program will serve as a primary administrative unit that oversees the collaborative resea...

Active RESEARCH CENTERS
BCM-TSU CURED Cancer Research Education Program (C-REP)
NATIONAL CANCER INSTITUTE Baylor College of Medicine United States 2023 – 2027

CURED C-REP Summary/Abstract The Collaborative Cancer Research Education Program (C-REP) of the Baylor College of Medicine (BCM)/ Dan L Duncan Comprehensive Cancer Center (DLDCCC)...

Active OTHER RESEARCH-RELATED
Methods Training for Comparative Effectiveness Research in Cancer
NATIONAL CANCER INSTITUTE University of Tx Md Anderson Can Ctr United States 2023 – 2028

Comparative effectiveness research (CER) aims to inform healthcare decisions by providing evidence on the benefits and harms of different alternatives in cancer care. While randomi...

$3.16M
USD
Active NON-SBIR/STTR RPGS
Engineered T cell-based imaging for glioblastoma and CAR-T cell tracking
NATIONAL CANCER INSTITUTE University of California, San Francisco United States 2023 – 2027

Molecular biology, genomics, and immunology are revolutionizing modern medicine by uncovering key molecular markers in human diseases. Imaging technologies that can directly visual...

$6.6M
USD
Completed SBIR-STTR RPGS
Assigning mode of action to phenotypically discovered anticancer leads.
NATIONAL CANCER INSTITUTE Attagene, Inc United States 2023 – 2025

ABSTRACT. Assigning the mode of action to bioactive compounds is an essential step in drug discovery and a major challenge in chemical biology. This problem is particularly acute f...

$10M
USD
Active NON-SBIR/STTR RPGS
Increasing Engagement in Patient Reported Outcome Measurement to Address Breast Cancer Care Disparities using Health Information Technology in Community Cancer Settings
NATIONAL CANCER INSTITUTE Brigham and Women'S Hospital United States 2023 – 2027

Project Summary/Abstract Major disparities in breast cancer-related outcomes have been widely documented across the cancer care continuum, with Black patients experiencing higher m...

$6.95M
USD
Active NON-SBIR/STTR RPGS
Genetic and Environmental risk of NAFLD-related HCC In All Latinos: the GENIAL Study
NATIONAL CANCER INSTITUTE University of Miami School of Medicine United States 2023 – 2027

The burden of hepatocellular carcinoma (HCC) due to non-alcoholic fatty liver disease (NAFLD) has increased substantially over the past two decades. Although both NAFLD and HCC dis...

$3.3M
USD
Active NON-SBIR/STTR RPGS
Engineered T cell-based imaging for glioblastoma and CAR-T cell tracking
NATIONAL CANCER INSTITUTE University of California, San Francisco United States 2023 – 2027

Molecular biology, genomics, and immunology are revolutionizing modern medicine by uncovering key molecular markers in human diseases. Imaging technologies that can directly visual...

$6.27M
USD
Active NON-SBIR/STTR RPGS
Genetic and Environmental risk of NAFLD-related HCC In All Latinos: the GENIAL Study
NATIONAL CANCER INSTITUTE University of Miami School of Medicine United States 2023 – 2027

The burden of hepatocellular carcinoma (HCC) due to non-alcoholic fatty liver disease (NAFLD) has increased substantially over the past two decades. Although both NAFLD and HCC dis...

$3.41M
USD