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21,042 grants found
Showing 14,121 – 14,140 of 21,042 grants
Decoding enhancer usage and gene expression of human heart development in 3-D cardioids
The early steps of heart formation during embryogenesis require precise spatiotemporal coordination between different heart progenitors to join together to form a beating heart tub...
Brain organoid-on-chip: a microfluidic platform to study neocortical development
A human model of neocortical development to understand neurodevelopmental disorders such as autism spectrum disorders or intellectual disability is urgently needed.Neural 2D cultur...
From Keyboard Warrior to Digital Army: Mapping Far-Right Networked Publics
The question driving the project From Keyboard Warrior to Digital Army: Mapping Far-Right Networked Publics (MAFNET) focuses on how far-right online communities recruit, radicalize...
Optimization of fast-ion confinement against edge instabilities for future fusion reactors
The project presented here deals with Fast-Ion Confinement OPtimization (FICOP) in magnetically confined fusion reactors.The goal of the project presented here is the characterizat...
Parallel epigenomic and apoptotic profiling to identify targetable sensitivities in Multiple Myeloma
Multiple Myeloma (MM) is an incurable cancer caused by uncontrolled growth of the plasma cells.A major challenge is drug resistance, which is caused by increased reliance on the an...
Determining Impact of Viruses on Biogeochemical processes In Soil
Microorganisms have a central role in soil biogeochemical processes. Essential functions include nutrient cycling, controlling greenhouse gas fluxes and supporting crop productivit...
The Russian automotive industry 1991-2020
Since the fall of the USSR, the Russian automotive industry has undergone enormous changes. The latter is inextricably linked to Western industrial groups.The present study is desi...
Spatially rEsolved Single-cell Approaches in Haematologic MalignanciEs
A global understanding of therapy response and therapy resistance in haematologic malignancies, including multiple myeloma and acute lymphoblastic leukaemia, in which cancerous cel...
Addressing molecular spin qubits by ESR-STM
The emergence of ESR-STM has recently opened new perspectives on the coherent manipulation of individual spin qubits. However, to date ESR-STM experiments are essentially focused o...
Dynamics of communities and Evolution of Antibiotic Resistance in Wastewater
Environmental antibiotic resistance is a major threat to human and veterinary health and a key issue addressed by the European One Health Action Plan Against Antimicrobial Resistan...
Development of a point-of-care microfluidic device for Therapeutic Drug Monitoring in cancer treatment (POC-TDM)
Cancer claims almost 10 million lives annually, making it one of the major causes of death around the world.Despite the development of novel drugs and treatment options, the 5-year...
Deciphering rhinovirus-mediated macrophages impairment through the establishment of human induced pluripotent stem cells-derived macrophages
A growing body of evidence suggest that viruses can modulate myeloid cells responses leading to long term impairment of monocytes/macrophages phenotypes.Whereas for virus directly...
Mechanics of Nanoporous W under irradiation
Fusion reactors demand materials capable of withstanding unprecedented extreme conditions.Refractory-based nanoporous metals offer a combination of mechanical and radiation perform...
Implacable Archives: Reviving Mário Pinto de Andrade’s Personal Archive
LUARC intends to contribute to the enhancement and revitalization of the personal archive of Angolan intellectual Mrio Pinto de Andrade (MPA).In addition to working with unique doc...
Extending the scope of Reduced Density Matrix Functional Theory for bosons
The one-body reduced density matrix plays a fundamental role in describing and predicting general quantum features of bosonic systems, such as Bose-Einstein condensation (BEC) or m...
Problem-based learning trajectories in discrete mathematics education
Our research project is inscribed into the domain of mathematics education (didactic of mathematics): a research domain at the interface of mathematics and social sciences.The proj...
Spatiotemporal analysis of mammalian embryonic development at single-cell level
Mammalian early embryonic development requires exquisite spatiotemporal gene regulation at the level of individual cells.However, it is still unclear and remains a fundamental chal...
Adipose tissue-Liver Macrophage CrossTalk in NASH and Fibrosis
Non-alcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis and damage. This drives liver inflammation, promoting the progression to non-alcoholic steatohepatit...
Detection and elimination of senescent cells targeting Cyclophilin D
Ageing-related diseases are tightly correlated with the accumulation of senescent cells.While the selective elimination of senescent cells is a primary therapeutical goal in the fi...
Recycling-oriented alloy design for next-generation of sustainable metallic materials
European industry increasingly focusses on recycling, pushing towards circular economy as part of EU Green deal. This offers enormous energy savings and CO2 reductions.However, the...