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21,042 grants found
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Paleodietary analyses of the first Andean cities: high-resolution assessment to macronutrients using a multiproxy approach.
Paleodietary analyses of the first Andean cities: high-resolution assessment to macronutrients using a multiproxy approach.The socio-ecological circumstances that underpinned the r...
Development of dual-targeting epigenetic modulators for polypharmacology-based cancer therapy
Cancer is a multifactorial disorder involving different genetic and epigenetic alterations.Since epigenetic modifications are brought about by multiple enzymes working synergistica...
Variational coarse-graining of lattice energies for crystal defects: Applications to partial dislocations and stacking faults
Defects are omnipresent in crystalline materials and the understanding of their emergence and interaction is essential for the prediction of the macroscopic material behaviour.Thus...
The Musical Avant-garde in Rome in the 1960s: Actors and Networks in Music History
ROMAVANTGARDE aims to reveal a particular phenomenon in the history of music: the effervescence of avant-garde networks in Rome during the 1960s.This phenomenon saw the first steps...
Ultracold polyatomic molecules for controlled chemistry and precision physics
Ultracold atoms have been successfully used in quantum simulations and precision measurements. Molecules possess a richer internal structure promising new applications. However, on...
Using CARDIac simulations to run in-silicO clinical TRIALS
Clinical trials are a key tool for advancing medical knowledge, but they consist of a long and costly process entailing the recruitment of a representative cohort of participants t...
Alternative gene ends: the crosstalk of RNA cleavage and transcription termination
The human genome contains only ~20.000 genes, however, most of them encode multiple transcripts resulting from alternative promoter usage, splicing, and 3’ end selection.Gene 3’ en...
The Effects of Far-Right Challenges on International Organizations
The rise of the far right poses a profound challenge to global politics.Diverse far-right actors, such as political parties, civil society groups, and social movements, have been g...
Measuring and Mitigating Risks of AI-driven Information Targeting
We are witnessing a massive shift in the way people consume information. In the past, people had an active role in selecting the news they read.More recently, the information start...
Towards a New Theory of Optimal Dynamic Graph Algorithms
Dynamic graph algorithms are of increasing critical importance.They are crucial for coping with dynamic networks, which model the ever-changing physical world, and have been instru...
Gestalts Relate Aesthetic Preferences to Perceptual Analysis
De gustibus et coloribus non disputandum est."" With this slogan philosophers and lay people alike have dismissed all attempts to understand taste, color perception, or a...
Morphing tubular structures for adaptive biomedical devices
Morphing tubular structures are extensively used in interventional medical devices (e.g., stents). Current solutions lack adaptability to complex geometries and to patient-specific...
DELta Virus infection in animal and human hosts
The emergence and rapid transmission of viruses pose increasing risks and challenges to modern societies, threatening public health and economic stability.A thorough understanding...
The fundamentals of cardiovascular calcification: from cells to therapy
With this project I propose to identify fundamental mechanisms of cardiovascular calcification (CVC) and new therapeutic targets using zebrafish as a model system.CVC, characterise...
Irritation and Human Sociality
Irritation is a pervasive feature of the human experience, and of human sociality in particular, yet it has been very little studied by social and natural scientists.Research on ir...
Engineering homeostasis into living materials
Engineered Living Materials (ELMs) are dynamically emerging at the intersection of synthetic biology and materials sciences and are providing solutions in a rapidly growing number...
Ocean Crime Narratives: A polyhedral assessment of hegemonic discourse on environmental crime and harm at sea (1982-present)
With the latest international Law of the Sea (UNCLOS 1982), narratives on environmental crimes and harms at sea have changed their views of ocean governance, sustainability, and hu...
Metaraminol Demonstration Plant as Commercialisation Blueprint for Sustainable Production of Pharmaceuticals using Enzyme Cascades
The development of more environmentally friendly synthesis methods is urgently needed if humanity wants to maintain an environment worth living in.The establishment of more biocata...
Printed Computing: Enabling Extremely Low Cost Pervasive Near Sensor Computing
A large number of important domains - such as fast moving consumer goods and personalized medicine - have still not seen the benefits of computing, mainly due to high production co...
Transmission of the human microbiome and its impact on health
The human microbiome is a key component of our own biology and has important biomedical applications, but while its composition has been studied in depth and linked with several li...