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21,042 grants found
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Automated High-throughput Behavioral Measurement in Co-Housed Mice for Safer and More Effective Psychiatric Drug Development
Drug development for psychiatric and neurological disorders requires extensive preclinical testing for validation of safety and efficacy. Preclinical investigation of Central Nervo...
Handshake Complexes of Chiral Nanoparticles and Proteins
Chirality, or the absence of mirror symmetry, is omnipresent in both biological and abiological forms of matter. Rapid progress has recently been achieved in the synthesis of chira...
Unraveling the Mysteries of Vibrational Strong Coupling
Polaritonic Chemistry is a new and exciting field that has emerged from the fusion of chemistry and cavity quantum electrodynamics. In this innovative realm, and specifically under...
Natural Auditory SCEnes in Humans and Machines: Establishing the Neural Computations of Everyday Hearing
In an office, on a metro, or at home, diverse sounds may be surrounding you: a computer fan, footsteps and indistinct chatter, distant cars, the train slowing down. These sounds sh...
A theory and model of the neural transformations mediating human object perception
In the blink of an eye our brain rapIn the blink of an eye our brain rapidly transforms the photons hitting our retina into a rich and detailed percept of the world as consisting o...
Enhancement of Memory- and Energy-related Properties of Fluorite Structured Ferroelectrics
For several decades, ferroelectric (FE) materials (particularly lead-based perovskite materials) attained wide attention for memory (non-volatile) and energy storage applications....
PYREPAX – Past, present, and future of the Pyrenean pastures
For centuries, the relationships between Pyrenean valleys were regulated by pacts called paceras. These agreements were intended to maintain peace between valleys (hence their name...
Observing the Mechanisms of Earthquake Nucleation
Earthquakes are one of the most expressive phenomena of our planet, able to suddenly reshape the surface of the Earth and affect countless lives every year. Any effort towards eart...
Smart Detectors for Darkfield X-ray Imaging
The main objective of this project is to improve the early detection and accuracy of lung disease diagnosis by developing a novel detector concept for dark-field X-ray imaging - a...
Using thermal limits to understand community response to climate warming
When will communities reach their upper thermal limits (i.e., their climate countdown)? A key challenge for ecology and conservation only to be addressed by understanding the biolo...
High-throughput ultrasound-based volumetric 3D printing for tissue engineering
Cardiovascular diseases are the leading cause of death globally. Efficient drug testing and disease models are needed to reduce their death toll. Myocardial cell constructs, e.g. s...
Recharge and Evapotranspiration Characterizations through Holistic Assessment for Responsible Groundwater managEment
Mediterranean “analogue” environments across the world have seen increased frequencies of droughts, with repercussions such as reduced availability of soil water for the vegetation...
Synthetic programmable artificial condensates for enzymatic reactions
Cells contain numerous membraneless organelles, also called biomolecular condensates referring to the liquid-like properties of these condensate droplets. Intrinsically disordered...
ERA CHAIR IN MULTIDISCIPLINARY AREA STUDIES
The proposed project, ERA-AREAS, establishes the Center for Multidisciplinary Area Studies (CEMAS) at the Faculty of Arts, Charles University, Prague (CUFA), under the leadership o...
Fermionic Fractional Quantum Hall Systems under the Microscope
Fractional quantum Hall (FQH) states are paradigmatic examples of strongly correlated topological quantum matter, combining geometric order and strong interparticle interactions. Y...
The Shelterin-chromatin interplay in telomere homeostasis and genome stability
The linear ends of eukaryotic chromosomes are formed by telomeres, nucleoprotein structures containing double-stranded TTAGGG repeats, ending in a single-stranded DNA 3-overhang. I...
Topological aspects of Generalized Descriptive Set Theory
My project lies at the intersection of set-theoretic topology and generalized descriptive set theory (GDST) on uncountable cardinals. Since the 1950s, topology has extensively stud...
LInking laNguage to psyChologicAl well-being in immigRant communitiEs
The critical challenges posed by the growing migratory movements, in terms of linguistic and cultural collisions, raise the need to deeper understand the acculturation processes fa...
Green fuels production, via direct and low-energy methane oxidation
This proposal, titled ""Green Fuel Production, via direct and low-energy Methane Oxidation"" (METtoFUEL), will tackle the urgent and large-scale environmental problem of methane em...
The Tipping Point from Genome Instability to Cancer
Cancer starts years to decades before diagnosis. Yet, early stages of tumor development are poorly understood. In particular, the precancer landscape of chromosome instability (CIN...