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21,042 grants found
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Scanning multi-modality microscopy of moiré quantum matter
Moir materials are a treasure of mind-blowing scope of phenomena, much of which is still to be discovered.Along with the great opportunities, perplexing experimental and theoretica...
Forecasting climate surprises on longer timescales
The Greenland and Antarctic ice sheets (GrIS and AIS, respectively) and the Atlantic Meridional Overturning Circulation (AMOC) are prominent examples of tipping elements in the Ear...
Atomic-Scale Tailored Materials for Electrochemical Methane Activation and Production of Valuable Chemicals
Electrochemical methane activation and direct conversion to methanol is highly attractive – a dream reaction that would convert a greenhouse gas into a valuable liquid fuel in a dr...
PAST & FUTURE MILLET FOODWAYS
Crop diversification critically mitigates agricultural risk for humanity.Identifying the environmental and cultural factors influencing the adoption and abandonment of staple foods...
The History of Feminist Political Thought and Women’s Rights Discourses in East Central Europe 1929 - 2001
This project will produce the first comprehensive and multi-disciplinary history of feminist political thought and women’s rights discourses in East Central Europe in a broad chron...
Targeted insula stimulations as treatment for autoimmune disorders
Inflammatory bowel diseases (IBD) are a group of chronic inflammatory conditions affecting the gastrointestinal (GI) tract, including Crohns and Ulcerative colitis.The prevalence o...
Taming Combustion Instabilities by Design Principles
Both, the energy and aviation sector rely on gas turbines, a combustion system continuously optimized since its invention during World War II. They constitute a main pillar for tom...
Democracies of the Alps. Issues, practices and ideals of politics in mountain communities, 1300-1500
DEMALPS studies late medieval mountain areas as the cradle of radically new political experiences, inspired by original values and practices of self-governance.The focus of the pro...
An injectable and programmable drug-eluting embolic device
This project aims to develop a novel platform for drug delivery and treatment for liver cancers.A first in its kind two-step acting platform is described in detail depicting an ear...
Personalised Bioelectronics for Epithelial Repair
Care of chronic wounds constitutes an enormous socioeconomic burden to the European Healthcare system calling for new strategies to support healing for wounds at risk.As a restored...
Re-thinking the Green Revolution in the Medieval Western Mediterranean (6th - 16th centuries)
As Mediterranean societies prepare for the impacts of climate change over the next few decades, a case study to inform their future resilience is associated with one of the definin...
PErPetuating Stemness: From single-cell analysis to mechanistic spatio-temporal models of neural stem cell dynamics
Neural stem cell (NSC) populations in the vertebrate brain generate adult-born neurons for plasticity, growth, and repair. Neurogenic and gliogenic capacity, based on long-term NSC...
A Global Evaluation of Public Policies to Mitigate and Reverse Land Degradation
Land degradation is one of the major sustainability challenges of our time. It is a driver of climate change, biodiversity loss, and water pollution, and reduces global agricultura...
Deciphering Cellular Networks for Membrane Protein Quality Control Decisions
Any cell and each of its organelles needs to interact with its environment.Membrane proteins, which span the plasma membrane and the multiple endomembranes of a eukaryotic cell, me...
Small molecule heparanase inhibitors as anti-metastatic cancer drugs
The Heparanib Proof-of-Concept project aims to establish the feasibility of our unique small molecule heparanase inhibitors as drug candidates for the treatment of metastatic cance...
Role of tissue-resident FOLR2+ Macrophages as Organizers of the Tumor Immune MicroEnvironment
The infiltration of CD8+ T cells in tumors is crucial for the development of immunity against cancer.We have recently identified a tissue-resident macrophage population expressing...
Tunnel ionization in three-dimensional tailored light fields
Tunneling is a non-resonant, quantum mechanical process without any classical analog.The electric field of a strong laser pulse can bend atomic and molecular potentials such that a...
Beyond mapping of the human brain: causal deconstruction of brain mechanisms underlying complex social behaviors
Social information pervades every aspect of our lives, and our ability to process it and respond appropriately is essential to our success as individuals and of society as a whole....
Entangled tertiary folds
The most sophisticated functions of proteins emerge at the level of their tertiary structure and involve large amplitude conformational changes.In contrast, the functions of synthe...
The Microbiota-Root-Shoot Axis in Plant Health and Disease
Since 450 million years, roots of healthy plant are colonised by diverse communities of bacteria, fungi, and oomycetes which are known to extend host functions by protecting roots...