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21,042 grants found
Showing 941 – 960 of 21,042 grants
Training network for tracking and controlling therapeutic immune cells in cancer
Cancer immunotherapies have been established in a growing number of clinical indications and the pace of development is massively accelerating. Currently over 6.000 clinical trial...
Towards observation-constrained UNderstanding and prEdicting of tropical Wetland mEThane emissions
Tropical wetlands dominate wetland methane emissions globally and play a vital role in recent surges of atmospheric methane. Despite the importance of tropical wetland methane emis...
The Medieval Book and Networks of Northern Europe c. 1000-1500: Texts, Crafts, Fragments
Medieval books were instrumental in shaping European history, communicating rituals, stories and ideas as they were read, copied and shared. To modern scholars they illuminate trad...
Making Sense of the Unexpected in the Gravitational-Wave Sky
General Relativity (GR) is more than a century old, but is still our best macroscopic description of gravity. Key GR predictions are black holes (BHs) and gravitational waves (GWs)...
Cosmic Bells: Unveiling the composition of neutron stars with tidal oscillations
Neutron stars (NSs) are among the densest objects in our Universe, yet what constitutes their interior remains unanswered. Recent studies suggest the existence of quark matter insi...
Motivic Stable Homotopy Theory: a New Foundation and a Bridge to p-Adic and Complex Geometry
This project is centered on the field of algebraic geometry and involves homotopy theory and analytic geometry. The overall goal is to unveil the underlying principles of a large v...
Lobbying (A)symmetry: The Dynamics Behind Informed Policy
The LOBBYMETRY project addresses two types of imbalances in lobbying: 1) mobilisation asymmetries, which exclude some actors from the policy debate, and 2) information asymmetries,...
Optimal algorithms and data structures for decomposing graphs by small cuts and separators
Graphs are structures consisting of vertices (points) and edges (lines connecting pairs of points). Graphs can model systems such as road networks (intersections connected by roads...
The Potential Link between Transmembrane Sensors and Nucleic Acid Remodeling in the Shango Anti-Phage Defense System
The SHARP (Shango Anti-phage Remodeling Pathway) project aims to explore the molecular mechanism of Shango system, a widespread bacterial anti-phage defense module. While the well-...
Deep-level modeling of novel germanium-based superconductive quantum devices
A great scientific and technical challenges of our time is to engineer a scalable quantum computer, and proximity-induced superconductivity is one of the most important ingredients...
Elucidating the role of nuclear metabolism in embryo implantation
Embryogenesis involves dynamic epigenetic and transcriptional changes as the zygote divides and cells differentiate into embryonic (epiblast) and extra-embryonic (primitive endoder...
Glycosaminoglycan biosynthesis: deciphering the divergent step
Glycosaminoglycans (GAGs) are negatively charged polysaccharides that form a key part of the extracellular matrix in animal tissues, from marine corals to humans. They play crucial...
Building Sustainable and Resilient Ecosystems with the Convergence of Nature-Based Solutions and Digital Technologies
In response to the pressing challenges posed by rapid urbanization and climate change, innovative urban solutions are needed. Nature-based solutions (NBS) and digital technologies...
Machine Learning-Assisted simulation of Metalloenzyme’s Reactivity
Metalloenzymes play a crucial role in various biological functions, going from small molecule transportation to catalyzing essential metabolic ingredients. Understanding their reac...
DeConstruct Stars: revealing the enigmatic mixing process in the radiative-convective boundary of stars using cutting-edge 3D numerical simulations
Stars like our Sun are complex systems in which hydrogen fusion occurs in the radiative core, and heat is transported by convection in the outer part. The two most important region...
Disk Instabilities in Highly Accreting Neutron Stars
Astrophusical accretion disks are the main engine of most of high energy sources. Although they have been studies for decades, we still do not know their exact structure and their...
Learning the Universe in the era of Precision Cosmology
I propose the project LUPCOS (Learning the Universe in the era of Precision COSmology) to be carried out at the Kapteyn Astronomical Institute, University of Groningen, under the m...
In-Materio Reservoir Computing Using Tailored Epitaxial Complex Oxides
The ever-increasing power consumption of electronics necessitates the development of new energy-efficient device paradigms for data storage and computation. In this pursuit, approa...
Phase, time and correlations in free electron wave packets
Electron emission from matter is a widespread phenomenon in nature, with examples including the photoionization of atoms and molecules, photoemission from solids, and the release o...
Next generation versatile and effective AAV-mediated large gene delivery
Despite 6 products on the market and dozens in advanced phases of clinical development, in vivo gene therapy with vectors derived from adeno-associated viruses (AAV) still faces th...