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21,042 grants found
Showing 861 – 880 of 21,042 grants
Probing nuclear parton dynamics in Heavy-Ion Collisions with Hard Probes
Perturbative QCD (pQCD) derived from first principles, is used to predict experimental observations involving large momentum transfer, such as high-energy jet productions in proton...
THE ROLE OF SYNAPSE POLARITY ON THE FORMATION AND PLASTICITY OF INHIBITORY CONNECTIONS
In adults, GABA acts as the primary inhibitory neurotransmitter, but during early development, GABAergic synaptic transmission has depolarising effects and can influence various de...
The role of SYNGAP1 isoforms in brain development
Synaptic Ras GTPase activating protein (SynGAP) is crucial for neuronal communication and is highly concentrated in excitatory synapses. Mutations in the SYNGAP1 gene cause SYNGAP1...
PHOS-SVD: PHOSpholipids in Cerebral Small Vessel Disease
Cerebral small vessel disease (SVD) is the leading cause of vascular dementia, plays a significant role in Alzheimer's disease and increases stroke risk, highlighting its critical...
Ultrathin Two-Dimensional Polymer Heterostructure Membranes Enabling Unidirectional Ion Transport
Current separation technology is crucial for many aspects of human life and accounts for ~15% of the worlds energy consumption. While the particle flow through separation columns i...
Delegating decisions: An overlooked way of pursuing immoral goals
Modern societies are tormented by warfare, crime, corruption, and environmental exploitation. If many people have prosocial goals and desire to see themselves and to be seen by oth...
Overcoming Mechanically-Induced Resistance to Chemo-Immunotherapy in Pancreatic Cancer
Cancer progression is closely associated with generation of mechanical stresses that cause the compression of tumor vessels, drastically reducing delivery of drugs. My co-workers a...
Evolutionary Arms Races Shaping the Germline Epigenome
Germline chromatin pathways are key to the stable inheritance of genetic and epigenetic information. They also participate in intense evolutionary battles between genetic entities...
Neuronal implementation of cognitive maps for navigation
Intelligent behavior is based on internal models of the world that enable mental simulations and strategic planning. A leading model to study such “cognitive maps” are networks of...
Central roles of mycobacterial type VII secretion systems in intra- and inter-kingdom warfare
Bacteria interact with their environment via specialised secretion systems that deliver proteins outside of the cell. Due to a bias in research efforts, for many years such systems...
New Direct Empirical Evidence on Wage Setting
Our project proposes to provide new empirical evidence on wage setting. This evidence will enhance our understanding of industrial relations, and of wage inequality.First, we will...
Antigen-specific treatments to target autoimmune kidney diseases
Chronic kidney disease (CKD) affects around 10% of the population worldwide and is associated with significant overall and cardiovascular mortality. CKD is a heterogeneous group of...
Optical Entanglement of Nuclear Spins in Silicon
A major breakthrough in quantum information processing is expected once “qubits”, carriers of quantum information, can be reliably integrated and controlled in silicon – the basis...
Design and Chemical Construction of Quasi-living Phagocytic Synthetic Cells for Artificial Phagocytosis of Bacteria
The growing occurrence of antimicrobial-resistant infections, compounded with the stalling development and approval of new antibiotic drugs, has created a therapeutic gap, threaten...
From RNA-peptide coevolution to cellular life at heated air bubbles
The origin of life on Earth is one of humanity's profound mysteries that lacks scientific answers. We aim to answer this fundamental question by performing pioneering experiments s...
TURN-TAKING AND TURNING POINTS IN VIOLENT ENCOUNTERS. TOWARDS AN EXPLANATORY THEORY OF HOW CONFLICTS IN URBAN PUBLIC SPACE BEGIN, TRANSFORM AND END
Although violent police-civilian and civilian-civilian encounters constitute a tiny sliver of the social interactions that take place each day, their consequences can be far-reachi...
Alternative Modernities and Everyday Life in the Pre-emancipation Southern Caribbean (c. 1634–1863)
ISLANDLIVES will be the first interdisciplinary historical archaeological project to deploy a broad array of cutting-edge archaeological science techniques to study everyday life a...
Ecological and evolutionary role of specialized bacteria in algae health and carbon sequestration
Marine algae fixing CO2 into organic matter is central to the global carbon cycle. While the food chain and marine bacteria consume roughly half of the fixed carbon, a harder-to-de...
Adaptive Separation using Dynamic Nanofibril Networks
This research program will develop materials, methods, and technologies that enable adaptive separation of molecules and particles using dynamic nanofibril networks. The ground-bre...
Privacy-Preserving Human MObility Trajectory Data GeneratOr
People travel and leave their location history as mobility trajectory data. This data is invaluable for a wide range of location-based services, including city planning, traffic co...