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21,042 grants found
Showing 7,501 – 7,520 of 21,042 grants
A revolutionary archaeological Pb observatory for astrophysical neutrino sources
One of the most energetic events in the Universe is the core-collapse Supernova (SN) where almost all the star's binding energy is released as neutrinos.These particles are di...
Efficient, safe, and cost-efficient RNA delivery vehicles for hard-to-transfect pre-clinical and therapeutic cells.
Human induced pluripotent stem cells (hIPSCs) have revolutionized the study of cell type-specific processes and the generation of organoids, tissues, and therapeutic cells for biom...
Biophysical Models of Bacterial Growth
Biology operates in a dynamic, changing environment, with fluctuations occurring over many time and length scales. Microorganisms are capable of duplicating themselves accurately o...
Micro-Macro Secure Control of Infinite-Dimensional Transport Systems
Although ""transport"" may imply different notions for different scientific fields, the feature of incorporation of interacting system components through which...
Mechanisms and evolutionary significance of hyperploidy variations in a long-lived parasitic cancer
Transmissible cancers are fascinating recently discovered biological entities.They have acquired the ability to cross host boundaries and spread between animals, even sometimes int...
Cascade Processes for Sparse Machine Learning
Deep learning continues to achieve impressive breakthroughs across disciplines and is a major driving force behind a multitude of industry innovations. Most of its successes are ac...
A Unifying Principle Underlying Social Bonding: Towards a Psycho-Biological Theory
Imagine a first date, where partners feel an immediate bond, versus an awkward date, where partners feel disconnected.BioBond asks whether there is a biological mechanism that is s...
Exploratory Program Synthesis
Our goal is to create Program Synthesis that can be used during Exploratory Programming to boost productivity and reliability when programmers write code. Program synthesis generat...
Black Narratives of Transcultural Appropriation: Constructing Afropean Worlds, Questioning European Foundations
How is Europe imagined by African, African European, and African diasporic writers?The research project argues that there is a temporarily and spatially expansive, only partially k...
Enantioselective screw-dislocation-mediated growth of chiral nanocrystals
In many scientific disciplines structural symmetry considerations are key.Specifically, mechanisms by which symmetry translates from atomic and molecular building blocks to crystal...
Engineering synthetic mechanotransduction through nucleocytoplasmic transport
Our understanding of cell biology has reached the point in which cells can be exogenously engineered to carry out specific tasks.This is typically applied to generate gene circuits...
Targeting Palmitic Acid Signaling Machinery to Inhibit Metastatic Cancer
Despite recent breakthroughs in immunotherapy and cancer research, metastasis continues to be responsible for 90% of cancer related deaths.While surgical resection and adjuvant the...
Advanced human models of the heart to understand cardiovascular disease
Cardiovascular diseases (CVD) are the cause of the highest mortality and morbidity rates worldwide and are expected to increase in coming years, leading to epidemic proportions.Tra...
A holistic approach to bridge the gap between microsecond computer simulations and millisecond biological events
Complete understanding of how complex biological objects operate and fulfill their cellular role requires at its core a detailed picture of the millisecond (ms) conformational tran...
ORGanic UPconversion device for SWIR imaging
Short-wave infrared (SWIR) imaging is a powerful tool to access and visualize the composition of (bio-)materials contact-free and in real time.It can be used for example for in-viv...
FunctIonal optoacousticS for imaging Early onsEt of Gut inflammation
The aim of this project is to functionalize contrast agents for multispectral optoacoustic tomography (MSOT) - a molecular ""sensitive"" ultrasound imaging tech...
Setting the optimal balance between metabolite supplementation and deprivation in cancer therapy
The goal of this proposal is to explore combinations of targeted metabolite supplementation and global nutrient restriction as a new strategy to reprogram tumor metabolism, to halt...
Quantitative multimodal pulse-and-label time-resolved chromatin maps
Chromatin packages the eukaryotic genome in a highly dynamic fashion, with dramatic structural changes during every cell cycle.At the same time, chromatin provides remarkable stabi...
New Horizons in Quantum Transport: From band structure geometry to emergent curved spacetime
The theory of electrical, thermoelectric and magnetoelectric transport lies at the core of condensed matter research, because it allows to probe many ground state properties as wel...
JWST Breakthrough in Galaxy Formation: Mass Build-up Efficiency at Cosmic Dawn
We present SFEER (Star Formation Efficiency in the Epoch of Reionization), an ambitious project to enable one of the most significant and long-lasting leaps in our understanding of...