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21,042 grants found
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Vascular Interactions and Remodeling during Gestation and its Impact on Neuronal functions
An intricate network of blood vessels perfuses the brain to support neural cells and carry signaling molecules from the periphery.It is mainly considered a rigid “transportation ne...
Lifting Design Drawings to 3D
Building on the outcome of the ERC Starting Grant D3 (ERC-2016-STG 714221), the objective of DLift is to demonstrate how our technology for reconstructing drawings in 3D can stream...
Deciphering fibrosis reversal mechanisms in chronic blood cancer for identification of novel predictive and therapeutic strategies
Fibrosis is estimated to be involved in 45% of global mortality, and currently no specific therapies for fibrosis in most organs exist. One central and controversially discussed qu...
Moving cell-based immunotherapies to fight bacterial lung infections into the clinics
Harnessing the immune system to combat global diseases has introduced a new era in modern medicine.The iMAClung proposal will extend this concept and will pave the way for the firs...
In-operando growth of organic mixed ionic-electronic conductors for brain-inspired electronics
The development of advanced brain-computer interfaces, wearable and implantable bioelectronic devices, prosthetics, and soft robotics requires the ability to process signals in a h...
A new technology to probe molecular interaction in cells at high throughput
Protein oligomers and aggregates are pillars of many cellular processes and can be associated with a number of life-threatening neurodegenerative diseases. These processes are ofte...
Inequalities in decision-making at critical junctions in life: The role of ability signals for sorting and selection
School track decisions, university or major choice, and initial job finding are all decisive for seizing life opportunities.When individuals from different socio-economic groups ma...
Optimization of Radio Detectors of Ultra-High-Energy Neutrinos through Deep Learning and Differential Programming
Detection of neutrinos at ultra-high energies (UHE, E >10^17eV) would be one of the most important breakthroughs in astroparticle physics in the 21st century and would open a ne...
The Milky Way as key to understanding the inward transport of matter to the centre of galaxies
Gas accreting onto supermassive black holes that sit at the centres of galaxies fuels the most powerful engines in the universe, Active Galactic Nuclei, shaping the formation and e...
Deciphering the origins of cell differentiation and developmental gene regulation in animals
During animal development the process of cell differentiation gives rise to terminally differentiated cell types with cell-type-specific gene expression programs.In the most closel...
Experimental replication of historical reanalysis processes
Background.In historical linguistics, reanalysis is described as process by which speakers assign a new meaning to a superficially unchanged element. Reanalysis is basic to grammar...
PEP4LEP 2.0 - Chemoprohylaxis for leprosy: comparing the effectiveness and feasibility of a community-based intervention to a health centre-based intervention in Ethiopia, Mozambique, and Tanzania.
BACKGROUND - Leprosy is a significant public health problem. Early detection, treatment, and prevention are crucial to reduce transmission and disabilities.The World Health Organiz...
Life is Science in a World turned Upside-Down
Our public events, held in conjunction with the European Researchers Night (ERN) in Graz, Austria, will be titled ""Life is Science in a World turned Upside-Down"&qu...
Epigenetic profiling of menstrual blood for precision cancer detection and prevention
Cancer has overtaken cardiovascular disease as the number one cause of mortality in high income countries, cancer incidence is increasing across the globe.Morbidity and mortality f...
Multi-omics characterization of descending motor circuits in the brainstem
The execution of coordinated and adaptive movements is the final manifestation of virtually all brain processes.Altered motor function is hence an associate feature of almost all c...
Non-invasive detection of interictal epileptiform discharges (IEDs) in the mesial temporal lobe (MTL) during sleep
Interictal epileptic discharges (IEDs) are pathological brain activities involving sharp spikes in electrical field potentials that occur preferentially during sleep.In epilepsy, I...
Machine-learning polymer Gel's ELasticity and Structure
Responsive soft materials, made of crosslinked polymer networks, have emerged as a promising class of systems.In particular, thermoresponsive hydrogels and microgels are widely use...
Anticancer Chaotropic PVA Micelles with DNA-motif-mediated Targeting
In this project, I propose an innovative nanoscale therapeutic system for the optimized delivery of ellipticine (Elli), as a proof of concept, to cancer cells.Utilizing polyvinyl a...
Interactions among Coherent Objects and the Origin of Collectivity in QCD at Colliders
The surprising findings of collective effects in nucleon-nucleus and nucleon-nucleon collisions (and very recently even in electron-positron collisions), previously thought to be e...
Bias-free high-performance solar NH3 production by perovskite-based photocathode and in-situ valorisation of glycerol
PECSolFuel aims to develop an environmentally benign bias-free photoelectrochemical device for energy-efficient NH3 production to replace the energy-intensive and fossil-fuel-drive...