Browse All Grants
21,042 grants found
Showing 4,761 – 4,780 of 21,042 grants
Decoding and Targeting Treatment-Resistant Metastatic Neuroblastoma
The childhood cancer neuroblastoma (NB) is a major challenge in pediatric oncology, and children with relapse have a very poor prognosis due to treatment-resistance at metastatic s...
Towards Shared Accountability: Rethinking the Locus and Scale of Assessment and Improvement in Education
Accountability has emerged as a central feature of educational governance worldwide.However, the prevailing accountability approach in education, the so-called performance-based ac...
Targeting the Metabolic Dependencies of Metastatic Tumor Cells
Metastasis is responsible for over 90% of deaths that occur in patients with cancer.So far there are no therapies that precisely target a metastatic disease due to the limited numb...
How to make a limb: a new insight using three-dimensional synchrotron palaeohistology
Tetrapods, i.e. four-limbed animals, are the only backboned animals to have truly conquered the land, and have achieved worldwide distribution in a wide range of environments.Sever...
Supramolecular microcapsules for bioreactor expansion of induced pluripotent stem cells
The SUPROTECT proof-of-concept project seeks to apply our squaramide-based (SQ) supramolecular materials to prepare microcapsules for the culture of pluripotent stem cells.Building...
Governing AI Technologies in Weapon Systems from the Bottom Up: Practices to Sustain and Strengthen Human Control
Autonomous and AI technologies have become integrated into the targeting functions of weapons.Algorithmic rather than human decision-making may therefore prevail in warfare, raisin...
A bio-archaeological study of 1,800 years of resilience and adaptation to urbanity
CityLife explores, from a bioarchaeological perspective, how historical populations adapted to an urban environment and developed resilience to the disadvantages of urban life.By e...
From the Third Pole to the Sea: impacts of melting glaciers and snowpacks on downstream water and food security
The high mountains of South Asia, often called ‘the Third Pole’, store large volumes of water in their glaciers and snowpacks. Twelve large river basins, fed with meltwater from th...
Lineage tracing of the human brain
Organisms develop through cell divisions generating clones that progressively organize to form different tissues. This process can be visualized as a cell phylogeny by lineage trac...
Positive Geometry in Particle Physics and Cosmology
There are strong indications from physics at both infinitesimal and cosmic distances that our current understanding of the laws of nature is only approximate, and must be replaced...
Gates to Language
Language is perhaps the most prominent feature that distinguishes humans from the rest of the animal kingdom.Nevertheless, many perceptual and learning mechanisms serving language...
Early life imprinting of B cell memory and its role in adult immunity
This proposal addresses the combined role of early life derived B cells in the adult immune system. Neonatal immune imprinting is now well-established concept.It emphasizes the imp...
High performance hydrophobic suberin nanoparticles for the generation of liquid-air biphasic droplets with application in food and therapeutics
An antibubble is a droplet of liquid with a shell surrounded by a thin film of gas.Antibubbles have many potential applications, e.g. drug delivery with application in a clinical s...
New Routes for the Solution NMR Investigations of Extra Large Biomolecular Assemblies
The cell is a collection of dynamic molecular machines.NMR spectroscopy is the method of choice to observe, at atomic resolution, complex conformational changes, transient interact...
Strange nuclear matter from first-principles hadron scattering amplitudes
StrangeScatt will assess the role of strange quarks in nuclear physics by performing first-principles computations of scattering amplitudes to study interactions between hadrons wi...
Feedback-control of the Microenvironment: Modular Organ-on-Chip Technology to elucidate the role of Neurovascular Stress in Schizophrenia
A well-controlled microenvironment is paramount for reproducible biomolecular studies.Organs-on-chips are in-vitro cell culture systems that employ microfluidic and biomaterial eng...
Photonic Vector Network Analyzers
The deployment of 5G networks and the upcoming deployment of 6G in the next decade is essential to advance wireless communication for keeping pace with modern data hunger. 6G will...
Mechanisms and biological functions of H3K27me3 reprogramming in plant microspores
How totipotency is established in germ cells is an essential question in reproductive biology.In the plant male germline, the haploid meiotic products microspores are totipotent, w...
Investigate maternal and paternal risk factors for violence during pregnancy: lasting impact for everyone
Globally, one in three women are estimated to experience physical and/or sexual intimate partner violence during their lifetime. Pregnancy is a life-changing time, when violence mi...
Temporal dependence of enhancer function
During vertebrate development, genes are regulated by distal regulatory elements, presumably via physical contacts between enhancers and transcription start sites.Alterations in en...