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21,042 grants found
Showing 20,861 – 20,880 of 21,042 grants
Skin micro-injector
Needle-based injections are very common in modern medicine, notably in ongoing vaccination efforts worldwide. However, needle phobia and infection risks affect patient compliance w...
Targetting neutrophil-mediated neurotoxicity for the treatment of Alzheimer's Disease
With the NeutrAD ERC PoC project, we present the first disease-modifying Alzheimers Disease (AD) drugs that abrogate leukocyte-mediated neurotoxicity and represent a novel class of...
Methyltransferase inhibitors for treatment of COVID19
Our IP secured drug DZNep is effective in treating SARS-CoV-2 infections in preclinical disease models and uniquely suppresses virus growth, triggers the innate immunity and facili...
A novel support material for 3D bioprinting and post-printing tissue growth: Print and Grow
Three-dimensional (3D) bioprinting holds great promise for tissue engineering, with extrusion bioprinting in suspended hydrogels becoming the leading bioprinting technique in recen...
Solid-State Ionics Synaptic Transistors for Neuromorphic Computing
Neuromorphic computing will revolutionize artificial intelligence for applications such as autonomous driving, smart diagnosis or natural-language understanding by emulating the op...
Repurposing a human drug to treat Alzheimer’s disease
Alzheimer’s disease is a major cause of disability among older adults and represents substantial financial and human costs to patients, families and societies worldwide. Currently...
A microRNA-regulated cell death-inducing gene therapy for T-cell Acute Lymphoblastic Leukemia
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy. Although outcome has improved throughout the years with the use of combined chemotherapy, the...
Versatile Polypeptide-based Intranasal Drug Delivery Platform(s) to Tackle CNS Disorders.
Nearly one in six of the world's population suffered from neurological disorders, this number is expected to keep growing. Many of those central nervous system (CNS) disorders do n...
Simplifying the SNAP-ADAR Tool for Broad Usage in Life Science Research and Drug Discovery
RNA base editing is a promising approach to manipulate genetic information in a transient and dosable way, which breaks new ground in basic Life Science research and drug discovery...
C- and N-terminal Epitope Conjugate immune Cell Targeted Vaccines
CNECT-VAX will validate the technical and commercial feasibility of a new cancer vaccine platform that uses nanobodies targeting dendritic cells to co-deliver antigens in vivo. As...
Rapid chip-based detection of antibiotic resistances
Drug-resistant infections are one of the greatest threats facing humanity. Antimicrobial resistance (AMR) causes over 700.000 deaths each year. Furthermore, AMR is associated to re...
Early warning systeM for soil dEgRadation: a statistical physics Approach to cLimate change aDaptation
Climate change is an urgent challenge and impacts ecosystems, society and economic activities. Here we focus on the problem of loss of fertile soil (soil degradation), a process th...
ELECTROCHEMICAL DNA-BASED SENSORS FOR IMMUNOTHERAPY MONITORING
During the initial part of the ERC-Consolidator Grant PRO-TOOLKITS we have successfully demonstrated a novel approach for antibodies detection. The platform uses antigen-conjugated...
Detection of pedestrians and cyclist outside a line of sight
The number of road accidents continue to increase dramatically each year. Cyclists and pedestrians, being a part of the daily traffic, keep challenging drivers thus making safety i...
Development of a revised plant synthetic biology toolkit to advance crop improvement
Agronomy faces significant global challenges such as coping with climate change, a need for more sustainable practices, and an increasing demand for more food of higher quality due...
Developmental immunotoxicity of perfluoroalkyl substances (PFASs) in a population of highly-exposed children
Exposures to perfluoroalkyl substances (PFASs), a class of persistent chemicals, have been linked to an array of adverse health outcomes including reduced antibody response to vacc...
Selective ethylene oxidation on novel curved model catalysts
Heterogeneous catalysis has made a wide range of highly functionalized materials available to us and therefore is an important contributor to economy and society. Ethylene epoxidat...
Posture and bodily movements in the Bible and biblical religions
Postures and movements are relevant for both a linguistic and a socio-anthropological investigation. From a cross-linguistic perspective, verbs of posture and motion show several i...
Research & Innovation For Cities and Citizens
The seven universities composing the European Universities Alliance “EC2U”, rooted in the dialogue between universities and cities, are again joining forces to extend the activitie...
Research for UNITA
The Alliance UNITA- Universitas Montium relies on the cooperation of six European universities, all romance language speaking, committed to foster the socio-economic development of...