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Showing 301320 of 201,169 grants

Active NON-SBIR/STTR RPGS
Novel Insights into Osteoarthritis, Pain and Function: MOST4
NATIONAL INSTITUTE ON AGING Boston University Medical Campus United States 2023 – 2028

OVERALL ABSTRACT The Multicenter Osteoarthritis (MOST) Study has been a major source of new knowledge about the course of OA and factors that affect it, having published over 180...

$115.14M
USD
Active COOPERATIVE AGREEMENT
Center for Braiding Indigenous Knowledges and Science (CBIKS)
National Science Foundation (US) University of Massachusetts Amherst United States 2023 – 2028

The natural and built environments of our modern world interact in complex ways that affect our global community. Understanding these interactions and their effects on society requ...

$115.03M
USD
Completed NON SBIR/STTR CONTRACTS
MONKEYPOX VACCINE CLINICAL TRIAL
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Leidos Biomedical Research, Inc. United States 2022 – 2024

To support a Phase II clinical trial evaluating alternative strategies for administering the JYNNEOS monkeypox vaccine to increase the number of available doses.

$114.98M
USD
Active COOPERATIVE AGREEMENT
University of Alaska Fairbanks / Sikuliaq Ship Operations - CY2025-2028
National Science Foundation (US) University of Alaska Fairbanks Campus United States 2025 – 2028

The overarching intellectual and technical merit of R/V Sikuliaq is in supporting the advancement of NSF peer-reviewed oceanographic research and education programs. In particular,...

$114.17M
USD
Active NON-SBIR/STTR RPGS
Tufts Clinical and Translational Science Institute
NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENC... Tufts University Boston United States 2023 – 2030

TUFTS CTSI OVERALL PROJECT SUMMARY Over its 14 years, Tufts Clinical and Translational Science Institute (CTSI) has brought together partners and collaborators and has grown prog...

$113.94M
USD
Active COOPERATIVE AGREEMENT
Track 4: Advanced CI Coordination Ecosystem: Monitoring and Measurement Services
National Science Foundation (US) Suny At Buffalo United States 2022 – 2027

The SUNY at Buffalo team provides monitoring and measurement services as part of the Advanced Cyberinfrastructure Coordination Ecosystem: Services & Support (ACCESS) program. Advan...

$113.58M
USD
Completed NON SBIR/STTR CONTRACTS
THIS IS A CONTRACT AWARD FOR VENTUREWELL TO PROVIDE SUPPORT FOR TECHNICAL ASSESSMENTS AND PROJECT MANAGEMENT FOR THE NIBIB RAPID ACCELERATION OF DIAGN
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Venturewell United States 2021 – 2021

The National Institute of Biomedical Imaging and Bioengineering (NIBIB) has an open solicitation for proposals to provide up to $500 million across multiple projects to rapidly pro...

$112.88M
USD
Completed NON SBIR/STTR CONTRACTS
Development of Therapeutic Products for Biodefense, Anti-Microbial Resistant (AMR) Infections and Emerging Infectious Diseases
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Revagenix, Inc. United States 2022 – 2025

To support the advanced development of candidate therapeutics for biodefense pathogens or emerging infectious diseases. The supported research and development activities will progr...

$112.71M
USD
Active NON SBIR/STTR CONTRACTS
ADVANCED DEVELOPMENT OF A VACCINE FOR PANDEMIC AND PRE-EMERGENT CORONAVIRUSES
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Duke University United States 2022 – 2026

To support the advanced development of candidate products for use following the intentional release of or in response to naturally occurring outbreaks of infectious diseases, inclu...

$112.48M
USD
Active NON-SBIR/STTR RPGS
Tufts Clinical and Translational Science Institute
NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENC... Tufts University Boston United States 2023 – 2030

TUFTS CTSI OVERALL PROJECT SUMMARY Over its 14 years, Tufts Clinical and Translational Science Institute (CTSI) has brought together partners and collaborators and has grown prog...

$112.16M
USD
Active NON-SBIR/STTR RPGS
Intermediate-Size Expanded Access Trial of Autologous Hybrid TREG/Th2 Cell Therapy (RAPA-501) of Amyotrophic Lateral Sclerosis
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND S... Massachusetts General Hospital United States 2023 – 2026

ALS is a lethal neurodegenerative disease accelerated by neuroinflammation. Current FDA-approved therapies have modest benefits and do not address inflammation. To address this, R...

$112.03M
USD
Completed NON SBIR/STTR CONTRACTS
FY21 CONSOLIDATED FACILITIES TASK ORDER C
NATIONAL CANCER INSTITUTE Leidos Biomedical Research, Inc. United States 2021 – 2024

In accordance with FFRDC SOW, Maintenance plans shall be compatible with elements of the current Interagency Agreement including any revisions thereto, between the U.S. Army Garris...

$111.94M
USD
Active NON-SBIR/STTR RPGS
Intermediate-sized Expanded Access Protocol for CNM-Au8 in Amyotrophic Lateral Sclerosis (ALS).
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND S... Columbia University Health Sciences United States 2023 – 2027

ABSTRACT Columbia University, Clene, and Synapticure are partnering and taking an innovative approach to provide persons living with amyotrophic lateral sclerosis ALS (pALS) acro...

$111.92M
USD
Completed NON SBIR/STTR CONTRACTS
ANIMAL MODEL DEVELOPMENT AND EFFICACY TESTING
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Sri International United States 2021 – 2023

This contract provides support services to develop a product against injuries resulting from radiation exposure to include development of and testing of medical countermeasures in...

$111.81M
USD
Active NON-SBIR/STTR RPGS
Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) Scientific Leadership Center
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Florida State University United States 2023 – 2029

Adolescents and young adults (AYA) under the age of 25 in the United States (US) are the least likely of all age groups to: 1) know their HIV status, 2) initiate PrEP if HIV-negat...

$111.62M
USD
Active OTHERS
NIH Cloud Platform Interoperability Administrative Coordinating Center
OFFICE OF THE DIRECTOR, NATIONAL INSTITUTES OF HEA... Research Triangle Institute United States 2022 – 2027

No Text

$110.65M
USD
Active NON-SBIR/STTR RPGS
Adult Changes in Thought (ACT) Research Program
NATIONAL INSTITUTE ON AGING Kaiser Foundation Research Institute United States 2021 – 2026

The Adult Changes in Thought (ACT) U19 Program will expand, modernize, and improve ACT's prospective cohort study to achieve advances in scientific understanding of older adults i...

$110.61M
USD
Active NON-SBIR/STTR RPGS
Adult Changes in Thought (ACT) Research Program
NATIONAL INSTITUTE ON AGING Kaiser Foundation Research Institute United States 2021 – 2026

The Adult Changes in Thought (ACT) U19 Program will expand, modernize, and improve ACT's prospective cohort study to achieve advances in scientific understanding of older adults i...

$110.41M
USD
Active NON-SBIR/STTR RPGS
Phase II randomized controlled trial of benfotiamine in early Alzheimer's Disease
NATIONAL INSTITUTE ON AGING Winifred Masterson Burke Med Res Inst United States 2022 – 2028

We propose a seamless Phase 2A-2B trial investigating benfotiamine, a prodrug of thiamine, as a first-in- class small molecule treatment for early Alzheimer's disease (AD). We cal...

$110.39M
USD
Active COOPERATIVE AGREEMENT
I-Corps: Continuation and Expansion of Training and Evaluation Support
National Science Foundation (US) National Collegiate Inventors and Innova... United States 2023 – 2026

The I-Corps program aims to increase the economic and societal impact of NSF research funding and other research funding by facilitating translation of technologies from the labora...

$109.63M
USD