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Active RESEARCH CENTERS
Pilot Projects
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES University of Montana United States 2021 – 2026

The Pilot Project program of the Center for Biomolecular Structure and Dynamics (CBSD) COBRE is designed to seed the research programs of junior investigators and to provide estab...

Active NON-SBIR/STTR RPGS
Models and Gene Therapies for AAT Deficiency
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE University of Massachusetts Med Sch Worc... United States 2021 – 2026

Administrative Core Project Summary The administrative core will provide a structure for management of the financial aspects of this complex multi-component program and create vehi...

Active NON-SBIR/STTR RPGS
Vector Immunology Core
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE University of Massachusetts Med Sch Worc... United States 2021 – 2026

CORE A - SUMMARY/ABSTRACT: The Vector Immunology Core will directly support all four projects of this program project grant by providing reliable, consistent and standardized immu...

Active NON-SBIR/STTR RPGS
Human Genetic Disease Modeling and Physiology Core
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE University of Massachusetts Med Sch Worc... United States 2021 – 2026

Core B - Project Summary To have successful therapies for Alpha-1 antitrypsin deficiency it is necessary to have animal models that recapitulate the phenotypes see in human patient...

Active RESEARCH CENTERS
Core A - Administrative
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Massachusetts General Hospital United States 2021 – 2026

PROJECT ABSTRACT The primary function of the Administrative Core within The Massachusetts General Hospital Harvard Center for Reproductive Medicine will be to provide an organiza...

Active RESEARCH CENTERS
Project 1 - Deciphering the Molecular Drivers of Rare Forms of Human Infertility Using Integrative Genomic, Cellular, and Phenomic Approaches
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Massachusetts General Hospital United States 2021 – 2026

PROJECT ABSTRACT Infertility affects up to 13% of childless couples yet the biological mechanisms underlying infertility and the effects of infertility on overall health remains...

Active RESEARCH CENTERS
Project 2 - Deciphering the Molecular Drivers of Common Forms of Human Infertility Using Integrative Genomic, Cellular, and Phenomic Approaches
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Massachusetts General Hospital United States 2021 – 2026

PROJECT ABSTRACT Infertility is a common condition that affects over one-tenth of couples attempting to conceive, and the costs of managing infertility exceed 18 billion US dolla...

Active RESEARCH CENTERS
Cytokine Profiling in Pediatric Obesity
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES Arkansas Children'S Hospital Res Inst United States 2021 – 2026

Targeting PBMC bioenergetics is a strongly supported strategy for modulating inflammation and preventing progression from obesity to type 2 diabetes. Our preliminary data show met...

Completed RESEARCH CENTERS
Loss aversion and cigarette smoking
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES University of Vermont & St Agric College United States 2021 – 2023

Cigarette smoking is entirely preventable but contributes to about 480,000 deaths in the United States and 8 million deaths globally each year. The role of personal behaviors in p...