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201,169 grants found
Showing 201,101 – 201,120 of 201,169 grants
Project 1: Elucidating the genetics and cell of origin of pancreatic cancer initiation
ABSTRACT (Project 1) Pancreatic ductal adenocarcinoma (PDAC) is a prevalent and almost uniformly fatal malignancy. Human PDAC genome sequencing has identified recurrent mutations...
Administrative Core
Administration – Abstract The Administrative Core represents the management entity designed to provide planning, implementation, oversight, evaluation and other required administ...
Project 2: Immune signals promoting pancreas cancer stemness and progression
ABSTRACT (Project 2) There is an urgent need to discover improved therapies for pancreatic ductal adenocarcinoma (PDAC), which require a better understanding of mechanisms unde...
Proteomics Core
Proteomics Core – Project Summary The broad objective of the Proteomics Core in the SC COBRE in Oxidants, Redox Balance, and Stress Signaling (Redox COBRE) is to provide state-of...
Cell and Molecular Imaging Core
Cell & Molecular Redox Imaging Core – Project Summary The South Carolina COBRE in Oxidants, Redox Balance and Stress Signaling (Redox COBRE) Cell and Molecular Imaging Redox Core...
Project 3: Impact of tumor genetics on PDAC immunobiology and responses to macrophage-targeted immunotherapy
ABSTRACT (Project 3) Pancreatic ductal adenocarcinoma (PDAC), an aggressive malignancy that is poorly responsive to treatment, is characterized by a prominent infiltration of imm...
Analytic Core
Analytical Redox Core – Project Summary The South Carolina COBRE in Oxidants, Redox Balance and Stress Signaling (Redox COBRE) Analytical Redox Core (ARC) offers infrastructure,...
Administrative and Biostatistics Core
ABSTRACT (Core A-Administrative and Biostatistics Core) This application seeks support for its efforts to discover, apply, and translate scientific knowledge about pancreatic c...
Core B: Human Pancreas
ABSTRACT: Stanford Human Bio-bank for Pancreas Cancer Research (Core B) The Stanford Human Bio-Bank for Pancreas Cancer Research (Core B) will support human tissue and cell stud...
Pilot Projects Program
Pilot Projects Program - Abstract The Pilot Projects Program (PPP) is an integral component of the COBRE in Oxidants, Redox Balance and Stress Signaling and supports our mission...
Core C: CODEX Core
ABSTRACT (Core C) A central focus of our program is understanding the roles of specific cell types, including immune cell populations, throughout the initiation, development and...
Administrative Core for the Air pollution disrupts Inflammasome Regulation in HEart And Lung Total Health (AIRHEALTH) Study
ABSTRACT: ADMINISTRATIVE CORE The overarching goal of the Administrative Core is to provide the operational support necessary to successfully achieve the goals we have laid out f...
Data Management and Analysis Core (DMAC) for the Air pollution disrupts Inflammasome Regulation in HEart And Lung Total Health (AIRHEALTH) Study
ABSTRACT: DATA MANAGEMENT AND ANALYTICS CORE (DMAC) Data Management and Analytics Core (DMAC) and the overall goals that provide support to the Scientific Human Biomarker Exposur...
Project 1 for the Air pollution disrupts Inflammasome Regulation in HEart And Lung Total Health (AIRHEALTH) Study
ABSTRACT: PROJECT 1 Air pollution, particularly particulate matter <2.5µm (PM2.5) comprising a variety of organic molecules produced by combustion, is a significant driver of chr...
Identifying Multidimensional Omics Profiles Associated with Cardiovascular and Pulmonary Responses to Chronic and Acute Air Pollution Exposure (Project 2) for AIRHEALTH Study
ABSTRACT: PROJECT 2 Lung and cardiac diseases are complex disorders with underlying chronic inflammation, which can be induced or worsened by exposure to air pollution. Thus, und...
Modeling Cardiovascular Risks of Air Pollutants with Human Induced Pluripotent Stem Cell-Derived Cardiovascular-Associated Cells (Project 3) for the Air pollution disrupts Inflammasome Regulation in
ABSTRACT: PROJECT 3 Air pollution, particularly particulate matter <2.5µm (PM2.5), penetrates into lung passageways and enters the bloodstream, causing respiratory, cardiovascula...
A biomarker for personalized care in post-stroke spatial neglect
This SPiRE provides the opportunity to raise the technical expertise of the PI (Barrett), and provide a critical missing element for personalized rehabilitation care in spatial ne...
STTR Phase I: Smartphone-based Biomechanical Analysis for Job Risk Assessment
The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to prevent work-related musculoskeletal disorders (WMSDs), a leading ca...
Doctoral Dissertation Research in Economics: Corporate Venture Capital and Its Impact on Young Firm Growth
This award is funded in whole or in part under the American Rescue Plan Act of 2021 (Public Law 117-2). High-growth young firms contribute considerably to U.S. job creation and...
Preventing Chronic Post-Surgical Pain and Prolonged Opioid Use: The Perioperative Pain Self-Management Program
Background: Surgery can precipitate the development of both chronic pain and long-term opioid use. Preoperative psychological distress is a risk factor for poor post-surgical outco...