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201,169 grants found
Showing 201,061 – 201,080 of 201,169 grants
An Assessment of Open Access Audio of the Clinical Encounter on Veterans and their Care
Background: The medical encounter can be overwhelming in term of the amount of information discussed, its technical nature, and the anxiety it can generate. Easy access to a secur...
Genetics & Clinical Cohorts
To achieve a 95% reduction of TB deaths by 2035 the WHO END-TB strategy states that critical introduction of new tools, such as a vaccine, drugs and treatment regimes, and a point...
Systems Biology, Bioinformatics, & Data Integration
Genome-wide research strategies provide unprecedented opportunities for insight but also major bioinformatic challenges due to the size and complexity of the data. The multidiscip...
M. tuberculosis strain-dependent interactions with host cells
Tuberculosis (TB) is a multifaceted disease that has extensive variation in clinical manifestations despite being the product of infection with a single pathogen, Mycobacterium tu...
Human macrophage variation & TB pathogenesis
Variation in clinical outcomes after Mtb exposure ranges from resistance to infection to disseminated disease. Human genetic and cellular mechanisms of resistance and disseminatio...
Mtb strain-dependent mechanisms of pathogenesis in mouse models
Tuberculosis (TB) is a highly heterogeneous human disease that develops in some, but not all, individuals who inhale 1-3 infectious bacilli of Mycobacterium tuberculosis (Mtb). TB...
Core A: University of Kentucky Alzheimer's Disease Core Center
Project Summary/Abstract: Administrative Core The ultimate goal of the UK-ADRC is to catalyze innovative and outstanding AD research while ensuring a more rapid rate of progress...
Core B: University of Kentucky Alzheimer's Disease Core Center
Project Summary/Abstract: Clinical Core The Clinical Core of the UK-ADRC maintains a well-characterized, community-based cohort focused on normal aging and early transitional dis...
Core C: University of Kentucky Alzheimer's Disease Core Center
Project Summary/Abstract: Data Management and Statistics Core The Data Management and Statistics (DMS) Core can be conceptualized as the lynchpin for integration of the ADRC Core...
Core D: University of Kentucky Alzheimer's Disease Core Center
Project Summary/Abstract: Neuropathology Core The overall objective of the Neuropathology Core of the UK-ADRC is to support research on normal brain aging, presymptomatic AD, MCI...
Core E: University of Kentucky Alzheimer's Disease Core Center
Project Summary/Abstract: Outreach, Recruitment and Engagement Core The Outreach, Recruitment and Engagement (ORE) Core plays a central role in achieving UK-ADRC goals by functio...
Core F: University of Kentucky Alzheimer's Disease Core Center
Project Summary/Abstract: Biomarker Core The theme of our UK-ADRC is Transitions from normal to late-life multi-etiology dementia, and the role of the Biomarker Core is to provid...
Core G: University of Kentucky Alzheimer's Disease Core Center
Project Summary/Abstract: Research Education Component The Research Education Component (REC) of the UK-ADRC offers a variety of research educational activities and comprehensive...
Administrative Core
ADMINISTRATIVE CORE: ABSTRACT Natives Engaged in Alzheimer’s Research (NEAR) will be organized into an Administrative Core, a Recruitment and Engagement Core, a Biospecimen Core,...
Research Methods Core
RESEARCH METHODS CORE: ABSTRACT Healthy People 2020 calls for research and policy to eliminate racial and ethnic disparities in health status, health behaviors, functional limita...
Recruitment and Engagement Core
RECRUITMENT AND ENGAGEMENT CORE: ABSTRACT Many American Indian, Alaska Native (AI/AN), and Native Hawaiian and Pacific Islander (NHPI) communities view academic research with ske...
Biospecimen Core
BIOSPECIMEN CORE: ABSTRACT American Indians and Alaskan Natives (AI/ANs) and Native Hawaiians and Pacific Islanders (NHPIs) are subject to disparities in many health conditions,...
Indian Transforming Alzheimer's Care Training
RESEARCH PROJECT 1: ABSTRACT The American Indian and Alaska Native (AI/AN) population is growing 3 times faster than the US all-races population. The number of AI/ANs aged 65+ is...
IKE Kapuna (Elder Wisdom) Project
RESEARCH PROJECT 2: ABSTRACT The prevalence of Alzheimer’s disease and related dementias (ADRD) is rising in Hawai`i, where it is projected that 10% of people aged 65+ will be di...
Cognition After OSA Treatment Among Native American People
RESEARCH PROJECT 3: ABSTRACT Prevalence of obstructive sleep apnea (OSA) among older adults in the US is as high as 56%. Short-term neurological consequences of OSA include cogni...