Browse All Grants
201,169 grants found
Showing 200,361 – 200,380 of 201,169 grants
CAREER: Harnessing Decision-focused Explanations as a Bridge between Humans and Artificial Intelligence
Artificial intelligence (AI) plays an increasingly prominent role in decision making in domains critical to society such as criminal justice, healthcare, and misinformation identif...
Studying interactions among metal nanoclusters, host ligands and small-molecule analytes
This project will investigate the molecular structures and photophysical properties of small metallic nanoparticles encapsulated in nucleic acids, termed DNA-templated silver nanoc...
SBIR Phase II: Resonant Sensors for Wireless Monitoring of Viable Cell Concentration in Small, Disposable Bioreactors
The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is the creation of a sensor system for cell-based manufacturing of such p...
CAREER: Tailoring the Selectivity of Electrocatalytic Reactions in Seawater and Brine
Renewable electricity from energy sources such as wind, solar, wave, and tidal can be used to drive chemical reactions, including the generation of hydrogen from water. The hydrog...
Collaborative Research: Improving Process-Level Understanding of Surface-Atmosphere Interactions Leading to Convection Initiation in the Central United States
Soil moisture is important for the climate system because it controls evaporation, transpiration, and energy movement from the land to the atmosphere. Through these mechanisms, soi...
Collaborative Research: Improving Process-Level Understanding of Surface-Atmosphere Interactions Leading to Convection Initiation in the Central United States
Soil moisture is important for the climate system because it controls evaporation, transpiration, and energy movement from the land to the atmosphere. Through these mechanisms, soi...
Louis Stokes Science, Technology, Engineering, and Mathematics (STEM) Pathways and Research Alliances: Louis Stokes Louisiana Alliance for Minority Participation (LS-LAMP)2020-25
The Louis Stokes Alliances for Minority Participation (LSAMP) program assists universities and colleges in diversifying the science, technology, engineering and mathematics (STEM)...
Model Based Deep Learning Framework for Ultra-High Resolution Multi-Contrast MRI
Sensitive imaging biomarkers are urgently needed for screening of high?risk subjects, determine early disease progression, and assess response to therapies in neurodegenerative dis...
Intermuscular coherence: A novel biomarker for upper motor neuron dysfunction in ALS
Project Summary/Abstract Amyotrophic lateral sclerosis (ALS) is a uniformly fatal neurodegenerative disease caused by neuronal death in the motor system, both in the brain and spi...
The impact of G-quadruplexes on genome evolution
PROJECT SUMMARY Apart from the double-helix B-DNA structure discovered by Watson and Crick, approximately 13% of the human genome comprises sequence motifs that can form non-canoni...
Experimental and computational analysis of mechanisms of mitochondrial-cellular ROS crosstalk in the kidney in salt-sensitive hypertension
PROJECT SUMMARY Salt-sensitive hypertension is a significant health problem worldwide and there is a need to understand the underlying molecular mechanisms to enable more effective...
Mitochondrial pyruvate transport in retinal health and disease
PROJECT SUMMARY/ABSTRACT The retina is the most metabolically active neuronal tissue in the human body. The defect in the energy metabolism of photoreceptor neurons and their suppo...
Serial immunotherapy combination to modulate the tumor environment in patients with metastatic gastroesophageal cancer
PROJECT SUMMARY/ABSTRACT Development of effective therapies is an urgent unmet medical need for patients with metastatic gastroesophageal adenocarcinoma (mGEA). The advent of immun...
Nonlinear performance analysis and prediction for robust low dose lung CT
1 PROJECT SUMMARY / ABSTRACT 2 Nonlinear algorithms such as model-based reconstruction (MBR) and deep learning (DL) reconstruction have 3 sparked tremendous research interest in...
Chemotherapy-driven evolution of the vascular secretome and its role in therapeutic resistance
PROJECT SUMMARY Our continued inability to develop selective therapies that prevent the emergence of disseminated breast tumor cells into lethal metastases necessitates new approac...
Role of ILC2 and eosinophils in abdominal aortic aneurysm
Abdominal aortic aneurysm (AAA) affects 0.5~3.2% of the general populations in US and worldwide. Besides adjusting lifestyle, open surgery and endovascular stent grafting remain th...
Hydrogen peroxide in endothelial function and dysfunction
The proposed studies will use new biosensors and novel chemogenetic approaches to identify the molecular mechanisms whereby reactive oxygen species (ROS) regulate nitric oxide (NO)...
Dissecting Connectivity and Function of Transplanted Interneurons in the Injured Spinal Cord
Injury to the cervical spinal cord results in an immediate and permanent loss of hand function due to massive disruption of neural circuitry. There are currently no effective thera...
Dynamics of protein kinase CK2 signaling in prostate cancer pathogenesis
Prostate cancer (PCa) is one of the major health issues for the aging Veterans population warranting investigations to further advance knowledge of the disease pathobiology and ben...
Structure and Function of Primate Retinal Circuits
An understanding of the normal structure and function of the retina is important to appreciate changes that occur during disease, development and aging. To this end, a longstanding...