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Showing 161180 of 44,293 grants

Active DIRECTED CALL GBP
Testing a causal model of sleep and circadian rhythm disturbance and youth- onset mood disorders
Wellcome Trust University of Sydney United Kingdom 2024 – 2029

We hypothesise that sleep and circadian rhythm disturbance (SCRD) is a pathophysiological mechanism underpinning a significant subset of youth-onset mood disorders called “circadia...

£305.83M
GBP
Active ATTRIVERSE: DEVELOPING DIGITAL SOLUTIONS FOR HEALTH IMPACT ATTRIBUTION GBP
Digital solutions for attributing climate change impacts on child nutrition and health (CLIMAKID)
Wellcome Trust Vrije Universiteit Brussel United Kingdom 2024 – 2027

Children in low- and middle-income countries are among those most at risk to the health impacts of climate change, not least through undernutrition, which has serious long-lasting...

£303.65M
GBP
Completed INNOVATIONS AIGH ENTERICS FLAGSHIP GBP
Development of a needle-free, high-density microarray patch (HD-MAP) delivering a typhoid conjugate vaccine (Vi-DT), to improve access to, and effectiveness of, Vi-DT
Wellcome Trust Sk Bioscience United Kingdom 2023 – 2025

Vaxxas and SK bioscience aim to generate data to demonstrate that further clinical development of Vi-DT HD-MAPs is warranted. This would be in the form of immunogenicity data in hu...

£303.51M
GBP
Active RESEARCH GBP
Developing an NIHR Health and Social care Delivery Research (HSDR) national evaluation team. The InterDisciplinary Evaluation of complex innovations in heAlth and Social care (IDEAS) Team.
National Institute for Health and Care Research Northumbria University United Kingdom 2025 – 2030

Our Team. The InterDisciplinary Evaluation of complex innovations in heAlth and Social care (IDEAS) Team will evaluate complex innovations in health and care services, organisation...

£302.88M
GBP
Active RESEARCH GBP
Biomarkers for RAtional Investigation for Neurological decision Support in TBI: BRaINS-TBI
National Institute for Health and Care Research University of Cambridge United Kingdom 2025 – 2028

In the UK ~1 million people attend emergency departments (ED) annually with mild traumatic brain injury (mTBI). The focus in an ED is to evaluate the requirement for a CT brain sca...

£302.81M
GBP
Active RESEARCH GBP
NIHR Global Health Group on Global Injury
National Institute for Health and Care Research University of Oxford United Kingdom 2024 – 2028

Aim: Across three Sub-Saharan Africa (SSA) nations (Malawi, Tanzania & South Africa) we will develop musculoskeletal (MSK) injury research capacity, centres of research excellence...

£302.67M
GBP
Active RESEARCH GBP
NIHR Global Health Research Group on Vaccines to Control Respiratory Pathogens & AMR across Africa (VacAMR)
National Institute for Health and Care Research University College London United Kingdom 2024 – 2028

RESEARCH QUESTION: Can control of infections & deaths due to respiratory pathogens & AMR be improved through vaccine & non-vaccine multimodal interventions? BACKGROUND: AMR-attr...

£302.64M
GBP
Active RESEARCH GBP
NIHR Post-TB CARE (Centre for Assessment and Research Excellence)
National Institute for Health and Care Research London School of Hygiene & Tropical Medi... United Kingdom 2024 – 2028

An estimated 155 million survivors of tuberculosis are alive today at high risk of biological, psychosocial and economic residual impairments, including death. Despite this need, p...

£302.63M
GBP
Active RESEARCH GBP
Towards patient centred care: Integrating TB and respiratory services in Africa
National Institute for Health and Care Research Imperial College London United Kingdom 2024 – 2028

Background: The burden of tuberculosis (TB) and chronic respiratory disease (CRD) remains unacceptably high in low and middle income countries (LMICs), with 10.6 million incident c...

£302.6M
GBP
Active RESEARCH GBP
Optimising Maternal and Perinatal Death Surveillance and Response to prevent future deaths
National Institute for Health and Care Research University of Southampton United Kingdom 2024 – 2028

Research question: Can perinatal and maternal deaths be reduced by implementation of a customised ‘Toolbox’ of interventions to optimise Maternal and Perinatal Death Surveillance a...

£302.58M
GBP
Active RESEARCH GBP
NIHR Global Health Research Group on Violence Against Women and Violence Against Children: University of Birmingham/University of Cape Town in partnership with the Lancet Commission
National Institute for Health and Care Research University of Birmingham United Kingdom 2024 – 2028

Question: How can we develop and adopt best practice in preventing violence against women (VAW)/violence against children (VAC) in diverse low resource settings? Background: VAW,...

£302.56M
GBP
Active RESEARCH GBP
Reducing childhood mortality and morbidity from injuries in Tanzania and Zimbabwe
National Institute for Health and Care Research University of Oxford United Kingdom 2024 – 2028

Research Question What are effective, sustainable, and cost-effective strategies that target the causes and consequences of child injuries in Tanzania and Zimbabwe? Background...

£302.55M
GBP
Active STRENGTHENING HEALTH AND DISEASE MODELLING FOR PUBLIC HEALTH DECISION MAKING GBP
Modelling dengue and chikungunya transmission patterns for improved public health decision-making in the Horn of Africa (AeDST-HORN)
Wellcome Trust Kenya Medical Research Institute United Kingdom 2025 – 2027

Africa is facing an increasing burden of mosquito-borne arboviral diseases primarily due to climate, land use and demographic changes. To support evidence-based decision-making in...

£302.51M
GBP
Active RESEARCH GBP
NIHR Global Group on COPD in primary care in South America (Breathe Well South America)
National Institute for Health and Care Research University of Birmingham United Kingdom 2024 – 2028

RESEARCH QUESTION How can we effectively implement good primary care pathways for diagnosis and management of COPD in South America, and reduce inequities? BACKGROUND Sou...

£302.47M
GBP
Active RESEARCH GBP
Nurturing the resilience of mobile youth to navigate health and wellbeing crises in southern Africa
National Institute for Health and Care Research London School of Hygiene & Tropical Medi... United Kingdom 2024 – 2028

BACKGROUND In South Africa and Zambia mobile adolescents and young people (mAYP) make up a significant number of the people who migrate. Migration limits mAYP access to health ser...

£302.1M
GBP
Active RESEARCH GBP
Improving outcomes for people with type 2 diabetes in Sub-Saharan Africa
National Institute for Health and Care Research University of Exeter United Kingdom 2024 – 2028

Research question How can we improve management of type 2 diabetes (T2D), particularly in lean individuals, in SubSaharan Africa? Background Over 20 million people live with T...

£301.92M
GBP
Active RESEARCH GBP
NIHR Global Health Research Group on Racism and Social Inequalities in Mental Health in Brazil (ORI)
National Institute for Health and Care Research University of Kent United Kingdom 2024 – 2028

RESEARCH QUESTIONS How does racism and social disadvantage impact on the mental health of Black Brazilians? How can we build capacity in research and healthcare around intersecti...

£301.63M
GBP
Active DISCOVERY AWARD GBP
Lipid mediated organelle-crosstalk controls cell-fate and function
Wellcome Trust University of Oxford United Kingdom 2025 – 2033

Mitochondria are dynamic organelles that play an essential role in determining the functions of the cell-types in the human body. Remodelling of the lipid composition of mitochondr...

£301.61M
GBP
Active RESEARCH GBP
NIHR Global Health Research Group Opt-AMR: Optimising Antibiotic Usage to Mitigate AMR
National Institute for Health and Care Research Liverpool School of Tropical Medicine United Kingdom 2024 – 2028

Research Question: Can regular surveillance of antimicrobial resistance (AMR) and antibiotic use (ABU) improve health worker prescribing practices and patient ABU leading to lower...

£301.01M
GBP
Completed CENTRES GBP
Project Cover Delivery Programme
Innovate UK Centre for Process Innovation Limited United Kingdom 2021 – 2024

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because...

£300.75M
GBP