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44,293 grants found
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Model Predictive Control of underwater floating-base manipulator systems in rough seas floating-base manipulator systems in rough seas
This project aims to exploit Model Predictive Control techniques supplemented with accurate, real-time wave data to perform precise compensation of the hydrodynamic disturbances ov...
Bio-Inspired Ultra-Compact Acoustic Transmitter - Bubbles as a Means of Weak-Source Amplification
The applicant has a formal offer for a fully-funded studentship in the EPSRC Centre for Doctoral Training in Future Ultrasonic Engineering (FUSE) is a partnership between the Centr...
Understanding how BCL3 promotes homologous recombination in colorectal cancer cells
Background: Colorectal cancer (CRC) patients often present at clinic with advanced disease (where the tumour has spread) making it more difficult to treat. Rectal cancer patients a...
Developing statistical, topological and geometrical techniques for ab-initio protein structure prediction
The project's aim is to develop techniques for reliably interpreting experimental small angle scattering data. This data can provide critical information regarding the varying stru...
Understanding and Exploiting Drug Reactivity with Lipid Membranes.
It has recently become apparent that lipids are reactive towards drugs that partition into membranes. The goals of this project are to understand the extent nature and consequences...
PH-Responsive Micelles for Controlled Enzyme Inhibitor Release
In this project, we will design pH-responsive micelles, loaded with the anticancer agent SAHA, to target effective drug deliver at the tumour site. The histone-deacetylase enzymes...
Biodegradable polymers for environmentally-friendly fabric care formulations
This project will focus on the development of new biodegradable polymers for applications in fabric care, improving the environmental footprint of an essential human activity - the...
Smart control of crop diseases: how can we best combine fungicides and plant resistance genes?
The project will investigate the interaction between the fungal pathogen Zymoseptoria tritici (Zt) and its host plant wheat. Zt causes septoria tritici blotch (STB), the most damag...
Addressing the challenge of combined heat and drought stress for cereal production
Drought currently restricts global cereal production by c.10% and is projected to worsen with climate change1. Researchers have recently identified agrochemical compounds that can...
Investigating the effect of a seaweed-derived common food ingredient (carrageenan) on the human gut microbiome
Carrageenan is a seaweed extract used extensively in prepared food including dairy, bakery and meat products. It is growing in popularity as a common food ingredient, however some...
Bioaccessibility of lipids from dairy products: the cheese matrix
The perception that milk and dairy products have adverse effects on health and risk factors for chronic diseases, especially cardiovascular diseases (CVD) is changing, mainly due t...
Regulation of Polarised Trafficking Machinery in Epithelial to Mesenchymal Transition.
During epithelial to mesenchymal transition (EMT), epithelial cells lose their apical-basal polarity and gain invasive properties. Currently, it is unknown how the regulation of tr...
"Bioprinting of smart deformable structures"
Yet to be determined.
RESpiratory monitoring reduCing drUg harm, the RESCU project
Scotland has the highest number of drug related deaths (DRDs) per capita out of any European country (National Records of Scotland, 2021). The majority of DRDs in Scotland occur du...
Songs of a Factory Girl: Ethel Carnie Holdsworth and Radical Working-Class Women's Writing
This PhD explores the radical writings and legacy of Lancashire mill-woman, Ethel Carnie Holdsworth (1886-1962), in collaboration with arts commissioning agency Mid Pennine Arts...
Laser surface micro/nano engineering of materials for the reduction of secondary electron yield
Laser surface micro/nano engineering of materials for the reduction of secondary electron yield
'Y gr a gyll y goron': poetry and politics in fifteenth-century Wales
The testimony of 'the poets of the nobility' (beirdd yr uchelwyr) has long been recognised as an invaluable source for the social, cultural, and political history of post-conquest...
Discovery and characterisation of novel mitochondrial damage-induced E3 ligases that regulate p-Ub
PINK1 and Parkin act in the same pathway to orchestrate mitophagy upon mitochondrial damage. Parkinson's disease patients with mutations in PINK1 and Parkin display a large range o...
Intersections of waste and unwanted materials and the lives of African street youth
Intersections of waste and unwanted materials and the lives of African street youth
Investigating the role of S-acylation in pancreatic beta cells
Correct insulin secretion from pancreatic beta cells is critical for human health, with defects in insulin secretion leading to hyperglycaemia, diabetes and its associated detrimen...