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44,293 grants found
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Aluminium alloy development for 3-D Printing
It is a very interesting project and I believe new high-performance aluminium alloys specially designed for AM is vital for the next generation of aluminium additive components....
Efficient bayesian inference and recycling of features in data analysis problems
The project is in collaboration with BT where large amounts of time-series data are collected along with vast amounts of potential predictors e.g. monthly telecommunications data w...
Localised control of directional growth: a multi-omics approach to understand protein translation at the hyphal tip in filamentous fungi
Filamentous fungi are a group of fungal species capable of very fast growth, named after their ability to grow long cells that resemble filaments. These fungi impact human lives in...
Biophysical interactions of NANOG
Embryonic stem cells arise during early embryo development and can turn into any cell type in the mammalian body. They can also self-renew, i.e., they can replicate without turning...
The role of metabolic priming in the translational response to glucose withdrawal
In Saccharomyces cerevisiae, glucose withdrawal produces a remarkably rapid and broad shutdown of protein production that is unique among stress responses. Bresson et al (2020) rec...
Multimodal Hydrogen Transport Refuelling Study
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because...
Elucidating Genetic Regulatory Networks in Alzheimer's Disease and Drug Repurposing
Background Alzheimer's Disease (AD) is a progressive neurodegenerative disease and is the most prevalent form of dementia. Currently, there are no therapies that directly affect d...
Computer Science (PhD)
"Fast and accurate methods of inference are vital for modelling in the natural sciences. These models tend to contain many free parameters, the inferring of which is a signica...
Laser und XFEL Experiment (LUXE) accelerator and physics studies
Quantum Electrodynamics (QED), the relativistic quantum theory how light interacts with matter, is currently the most precise theory in science. The precision of this theory is bas...
Biorefining Protein from UK Grasslands - Can We Combine Novel Protein with Surplus Bread Crusts to Sustainably Feed Healthier Food to More People?
British grassland farming covers 72% (12.6 million ha) of the utilised agricultural area, supporting 9.7 and 34 million cattle and sheep respectively1. Coupled with the drive towar...
Resilient and Flexible Railway Multi-Energy Hub Networks for Integrated Green Mobility
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because...
Mapping of subsurface minewater resources against surface demands
Decarbonising heating and cooling, and the wide rollout of thermal storage are some of the greatest remaining challenges to decarbonising our energy system. Heating currently accou...
Understanding the central kinematics of massive star clusters: Evidence for massive black holes?
The aim of the project is the study of the central kinematics of globular clusters, massive star clusters orbiting in the gravitational potentials of all major galaxies. A range of...
Development in Post-Colonial West Africa: Building the Nation
State led development projects were characteristic of the end of colonial rule in 'British West Africa' and the transition to new independent governments. Infrastructure, prestige...
Tackling Smoking in Wales
Background: Action on Smoking and Health Wales is Wales’s national charity seeking to reduce the harm and inequality caused by tobacco. Wales is formulating a new tobacco control p...
Electronic cigarette packaging in context: an exploratory study
Background Smoking is the greatest modifiable risk factor for cancer. Electronic cigarettes may reduce cancer risk by increasing the number of people who stop smoking successfully...
Early Detection with Urine and Cognitive Assessment Multiplex (The EDUCAM study)
Background: Cancer screening has demonstrated efficacy in reducing cancer burden. However, methods used are unsuitable for brain cancer due to its low incidence, the risks (e.g rad...
Integrated characterisation of anti-tumour immunity following neoadjuvant immunotherapy of hepatocellular carcinoma
Background Surgery can be a potentially curative treatment for early-stage hepatocellular carcinoma (HCC). However, 70% patients relapse within 2 years after resection. To improve...
MECCA: Metastatic Evolutionary dynamics of Colorectal CAncer
BACKGROUND People with metastatic colorectal cancer (mCRC) are unlikely to survive for 5 years following their diagnosis. Metastasis is an evolutionary process, but the lack of und...
Understanding and harnessing the antigenicity and adjuvanticity of combination oncolytic virus and targeted drug immunotherapy
Background: during our current programme we have investigated combination immunovirotherapy, including with targeted small molecules. We have uncovered immune-mediated enhancement...