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44,293 grants found
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Gendered Relations in Elite Occupations. A Comparative Study on Elite Selection and Careers
Sequence analysis
Determining the role of the ADMA-DDAH1 pathway in ischaemic stroke
Asymmetric dimethyl arginine (ADMA) is an endogenously produced inhibitor of nitric oxide (NO) synthesis and as such exerts significant effects on vascular homeostasis. ADMA is pri...
Causes and consequences of mental health challenges in autistic individuals during the transition to adulthood
Research Questions Autistic individuals1 face profound challenges across their lives, including high rates of mental health problems. Many of these mental health problems emerge du...
Development of epoxy-tiglianes as novel small molecule therapeutics for impaired re-epithelialisation associated with non-healing, chronic skin wounds in the aged
Normal (acute) dermal wound healing occurs through a series of phases, to induce wound closure and restore skin barrier function. However, non-healing chronic wounds, such as venou...
New care home admission after hospitalisation - understanding trajectories and predictors using linked health and social care data
Introduction: When used appropriately, admission to a care-home makes a positive contribution to the care landscape, offering best care to individuals who require this level of sup...
Molecular Dissection of Conjugative Transport in Gram-negative Bacteria
Type 4 secretion (T4S) systems mediate transfer of DNA from one bacterium to another in a process called "bacterial conjugation". As a result, T4S systems are crucial players in th...
The Jalview Resource for Biological Sequence, Structure and Function Analysis: 2019 and Beyond
The Jalview Resource is an open-source, GPL-licenced, graphical multiple sequence alignment editor and analysis workbench, first developed in 1996. It is installed on >57,000 compu...
DNA replication forks and checkpoints
The DNA replication checkpoint senses perturbation of DNA replication forks by a wide variety of agents. We know the protein components and the overall architecture of the checkpoi...
Exploring mitochondrial metabolism in health and disease using targeted biological chemistry
The molecular mechanisms by which mitochondrial reactive species, metabolites and redox signals contribute to physiology and pathology are unclear. This is in large part because th...
Cellular dissection of Plasmodium falciparum erythrocyte invasion
Plasmodium falciparum parasites still cause nearly half a million deaths each year. The repeated emergence of antimalarial drug resistance and the lack of a highly effective vaccin...
Action in Vision
How do vision and motor actions interact? A textbook will answer that vision guides movements but this view has been challenged over the last decade. The most striking realisation...
Expressive Life Writing and Telling During Crisis: Addressing Urgent Needs in the Akkar Governorate, Lebanon
The Lebanese financial crisis has caused significant loss of incomes for households, creating a food security crisis. The Lebanese currency has been reduced in value by 80%. The re...
Maths Research Associates 2021 QMUL
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because...
Strategic Alliances, Platforms and Ecosystems for the Digital Transformation of Industrial Firms
During the fourth industrial revolution, industrial firms have begun to carry out transformation projects that should allow the firms to change their manufacturing systems towards...
University of Exeter and City Science Corporation Limited
To enable the rapid development of novel optimisation tools for transport and energy networks, by developing and embedding optimisation tools and capabilities.
Developing a sustainable and high performance biofabricated leather-like material
In the UK and globally the fashion industry has been severely disrupted by the COVID-19 pandemic with shifts in consumer demand and supply chain disruption. Moving forward, consume...
Use of creep-plastic analysis methods to predict complex non-isothermal loading cycle crack growth and nucleation behaviour
Models developed by RR for creep and plasticity have been shown to provide a valuable insight into nominally complex fatigue and crack growth behaviour. Using stabilised stresses p...
University of Surrey and VG Systems Limited
To develop a novel methodology for undertaking XPS depth profiling of different materials.
Advancing influenza antigenic analysis to improve vaccine effectiveness
My project aims to help make the flu vaccine more effective. Flu is a common illness that people catch many times in their lives. Flu can cause severe disease or death, particul...
Communication and Non-Speaking Children with Physical Disabilities: Opportunities and Reflections from Design-Oriented Research
Non speaking children with severe physical disabilities experience the world differently compared with children who use natural verbal speech. Connected to their bodily impairments...