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44,293 grants found
Showing 43,601 – 43,620 of 44,293 grants
Mindset Teams in the Scottish education system (PHIRST Insight)
The aims of the evaluation are to:a) determine the impact of the Mindset Teams intervention on pre-specified outcomes relating to teachers and young people;b) explore the implement...
Digital first primary care for those with multiple long-term conditions: The views of patients, carers and health professionals
Background and rationaleGeneral practices across England are facing the pressure of rising patient demand alongside an increase in the complexity of the care required by patients,...
A Randomised Phase III Trial Comparing Intermittent with Continuous Treatment Strategies in chronic lymphocytic leukaemia (CLL)
DesignA prospective, multicentre, open-label, randomised, controlled, 2-arm, parallel-group, non-inferiority study to comparing an intermittent treatment strategy (experimental arm...
NIHR Development and Skills Enhancement Award
Training Award
BioEP: From prototype to clinical evaluation
Background 125,000 people attend a first seizure clinic annually with suspected epilepsy. 40,000 eventually receive an epilepsy diagnosis following an average delay of 1-year and w...
Digitally adapted, hyper-local realtime bed forecasting to manage flow for NHS wards
For the proposed project, we request funding for 2-years covering one software engineer, and one post-doctoral research associate supported by the assembled project team including...
Personalised Preoperative (Neoadjuvant) Chemotherapy (NACT) to Optimize Curative Treatment in Breast Cancer
Background: No effective method is available to predict, prior to NACT, which recipients' tumour will achieve the best response - a pathological complete response (pCR). Accur...
SMARTT Critical Care Pathways - (Safe, Machine Assisted, Real Time Transfer) An artificial intelligence based decision support tool to enable safer and more timely critical care transfer
Background: With an approximate cost of £2000 per bed per day for ICU patients and no evidence of consistent guidance between or within sites for when a patient is ready...
COVID-19: Coronavirus STORY (Serum Testing of Representative Youngsters), BAME cohort
COVID-19: Coronavirus STORY (Serum Testing of Representative Youngsters), BAME cohort
Inter-CEPt: Intervening to eliminate the centre effect variation in home dialysis use
RESEARCH QUESTION What are the factors driving centre variation in uptake of home dialysis, and how do these inform the design of an intervention bundle to overcome this?BACKGROUND...
Evaluating the Impact of Group Interpersonal psychotherapy (IPT) In Lebanon and Kenya on child developmental outcomes, maternal Depression and the mother-child relationship
Research Question: Does culturally-adapted group IPT delivered in community settings in Kenya and Lebanon have a greater impact on child developmental outcomes, maternal depression...
In-home Tracking of glaucoma: Reliability, Acceptability, and Cost: the I-TRAC Study
The research outlined in our proposal will determine the feasibility and acceptability of digital technologies to monitor glaucoma at home and inform the possible need and design o...
Double blind comparison of optimised Deep Brain Stimulation for severe Tourette syndrome
The aim of the project is to assess if optimised Deep Brain Stimulation (DBS) of the internal globus pallidum (GPi) reduces tic severity in patients with severe Tourette syndrome (...
Behavioural interventions to treat anxiety in adults with autism and moderate to severe intellectual disabilities (BEAMS – ID)
Background: A large number of people with autism and intellectual disabilities have problems with anxiety.There is good evidence that talking psychological therapies are an effecti...
The clinical and cost-effectiveness of Stimulant compared with Non-stimulant medication for adults with Attention-deficit / hyperactivity disorder and a history of Psychosis or biPolar disordER: SNAPPER
Background: Attention-Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder involving inattention, hyperactivity and impulsivity that starts in childhood an...
Why are we stuck in hospital? Understanding service user, family and staff perspectives when transforming care for people with learning disabilities and/or autism
Transforming care so that people with learning disabilities and/or autism can receive support at home rather than in inpatient units, secure settings or assessment and treatment un...
Deep infiltrating endometriosis: management by medical treatment versus early surgery: DIAMOND
Research questionWhat is the clinical and cost-effectiveness of laparoscopic surgery (with or without adjuvant medical treatment) versus medical management alone in women with deep...
Assessing SYmptom-driven versus Maintenance Preventer Therapy for the Outpatient Management of AsThma In Children (ASYMPTOMATIC)
Background: Asthma affects 1.1 million children in the UK. They have cough and difficulty breathing because of airway inflammation. These worsen during acute attacks, which are tre...
Reducing Health Inequalities through General Practice: A Realist Review (EQUALISE)
BackgroundThe gap in life expectancy between least and most deprived areas of England has increased in recent years to 9.4-years for men and 7.4-years for women. This gap is primar...
A randomised controlled trial and feasibility study of the effects of an e-health intervention ‘iSupport’ for reducing distress of dementia carers, especially in the ongoing pandemic of COVID-19.
Background: Most of the 850,000 people living with dementia in the UK are cared for at home. Caregiving is known to have a detrimental effect on physical and mental health. Covid-1...