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44,293 grants found
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Quantum Sensing for the Hidden Sector (QSHS)
Identifying the nature of the dark matter that dominates the mass distribution of galaxies and that plays a key role in our understanding of cosmology is a central unsolved problem...
Biologically inspired adaptive mechanisms for artificial neural networks
Relational reasoning is a crucial cognitive capacity of humans and other non-human animals and it can be viewed as an generalized concept of a task rule that can be applied wheneve...
Characterising the Evolution of Molten-Salt Solid Interfaces in Supported Membranes for Carbon Dioxide Separation
The overall aim of this PhD is to investigate and characterise the evolution of molten-salt solid interfaces with different compositions, under a variety of operating conditions. T...
Speakers, Listeners, Languages: Patterns Of Variability And Contrast In Spoken Language Dynamics
The goal of our proposed project is to shed new light on how the basic dynamics of speech production and perception are shaped by language-specific linguistic structure and may, at...
Autism - Understanding Developmental trajectories, and Inequalities in diagnosis and Treatment in adults aged 50 and over (AUDIT-50)
Background/aims: About 240,000 UK adults aged 50-years and over (≥50) have an Autism Spectrum Disorder (hereafter called autism*). The sparse evidence suggests they have poor outco...
Targeting RUNX to attenuate adverse cardiac remodelling and progression to heart failure
Myocardial infarction (MI) is a leading cause of heart failure (HF) and death worldwide.Preservation of contractile function and protection against adverse cardiac remodelling are...
Do dual anti-platelet treatments (DAPTs) protect the coronary microcirculation of the injured and diabetic heart?
Muscle damage and heart failure still occurs in a significant proportion of heart attack patients following a primary percutaneous coronary intervention (PCI). Furthermore, poorer...
SIPA2: Improving the Pharmaceutical Care of Older People with Sensory Impairment
Older people are: affected disproportionately by sensory impairment (SI); hearing, visual and dual; more likely to use polypharmacy (> 4 medicines); and to live alone.Older peop...
Immunometabolic cross-talk in the inflamed diabetic heart
Diabetic cardiomyopathy (dbCM) is a complication of type II diabetes (T2D), characterised by systemic inflammation, impaired cardiac function and disrupted metabolism.However, the...
Lancet Commission on Gender and Global Health
We are launching a Lancet Commission on Gender and Global Health that intends to ensure that global health take gender into consideration.A continued failure to consider and act on...
Defining the pathophysiological mechanisms underlying Low VWF in the Low VWF in Ireland Cohort (LoVIC) study
Von Willebrand Factor (VWF) is a protein that blood needs to clot normally. VWF is made by cells that line our blood vessels called endothelial cells. About 1 in 100 people inherit...
Drug transport through human peptide transporters
The human proton-coupled oligopeptide transporters PepT1 and PepT2 play a crucial role not only in the absorption of dietary nitrogen in the form of di- and tri-peptides, but also...
Determining the roles of the Artemis nuclease in genome stability at the replication fork
Damage to DNA occurs constantly within our cells. If this damage is not repaired, it can lead to mutations in our genome when cells divide, which can cause cancer. So, to protect t...
Diagnosing and dEtermining the contribution of small FIbre NEuropathy to pain in FibroMyalgia Syndrome (DEFINE-FMS)
We hypothesise that the rapid non-invasive diagnostic imaging technique of corneal confocal microscopy (CCM) can detect small fibre neuropathy in people with fibromyalgia syndrome...
Systematic evaluation of community development through open science training and incentivising contextual mentorship in health research
Open Life Science (OLS, https://openlifesci.org/) offers a 16-week long cohort-based training and mentoring programme that enables researchers to learn about, reflect on and integr...
Normative vs. Descriptive Accounts in the Philosophy and Psychology of Reasoning and Argumenta-tion: Tension or Productive Interplay?
It is a longstanding insight (Hume, 1740) that the normative and descriptive are different in kind so that inferring an is from an ought or vice versa is fallacious. Just because t...
A platform for studying the role of haemodynamics in microvascular disease
In order to function, all cells in the body require a regular supply of oxygen and continuous removal of waste products. Both are provided by blood delivered through the microvascu...
Upgrading the Fuzzy Dark Matter Model
The project will illuminate implications for cosmic structure formation of the hypothesis that dark matter consists of ultra-light scalar particles, generically labeled as Axion-li...
Building capacity in third-generation genomics and bioinformatics for agricultural biosciences in Africa
Doctoral Training Partnerships: a range of postgraduate training is funded by the Research Councils.For information on current funding routes, see the common terminology at https:/...
Swarms for Sampling and Detection of Life in Caves on Earth and in Space
Main Objectives: - Design and test a swarm of robots for the sampling and the detection of life in caves on Earth - Optimise swarm behaviour/design to find the strongest possible e...