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44,293 grants found
Showing 281 – 300 of 44,293 grants
A PROspective double-blind placebo-controlled multicentre trial of faecal MIcrobiota tranSplantation to improve outcomEs in patients with cirrhosis - PROMISE trial.
There is an evolving crisis of chronic liver disease (CLD) in the UK with prevalence and mortality increasing exponentially. End-stage CLD, termed cirrhosis, is the third biggest c...
University of Bradford MHLA
Bradford, the 7th largest city in England, has a diverse population with a range of socioeconomic profiles. It includes some of the most affluent wards outside of London, and highl...
Mental Health Leader Award: Teesside University, University of York, and Tees, Esk and Wear Valleys NHS Foundation Trust
I. Information on the geographical target area Teesside University (TU), the mentee Higher Education Institution (HEI), is situated in Middlesbrough, Tees Valley (TV), within th...
Effectiveness and cost-effectiveness of a peer-delivered, relational, harm reduction intervention to improve mental health, quality of life, and related outcomes, for people experiencing homelessness and substance use problems: The ‘SHARPS’ cluster randomised controlled trial.
Research question Is a peer-led harm reduction relational 12-month intervention for problem substance use among people experiencing homelessness, delivered in social care settings...
A randomised controlled trial of regular MRI scans compared to standard care in patients with prostate cancer managed using active surveillance
Research question In patients on active surveillance for prostate cancer, can regular MRI scans better detect prostate cancer progression, defined as grade or stage progression,...
Public Health Intervention Responsive Studies Team: PHIRST Light
Scientific Abstract We are a successful collaboration of Nottingham, Loughborough, and Lincoln Universities with an internationally-recognised track record of high-quality public...
The impact of extreme weather events on the mental health of vulnerable populations in Africa (WEMA project)
Climate change is projected to further increase the number and severity of heatwaves, floods and droughts, causing a disproportionate increase in injury, illness and death in resou...
The use of neuromuscular electrical STIMulation as a treatment for sarcopenia in people on HaemoDialysis
Research question: is a programme of neuromuscular electrical stimulation (NMES) effective in improving or reversing the condition of sarcopenia in people undergoing maintenance ha...
Public Health Intervention Responsive Studies Team: PHIRST LiLaC
LiLaC comprises researchers from Liverpool and Lancaster universities, collaborating with Directors of Public Health and members of the public, ready to deliver a Public Health Int...
Administrative Data Research UK - ONS
ADR UK (Administrative Data Research UK) is a partnership transforming the way researchers access the UK’s wealth of public sector data, to enable better informed policy decisions...
Public Health Intervention Responsive Studies Team: PHIRST Elevate
The proposed Public Health Intervention Responsive Studies Team (PHIRST-Elevate) is comprised of experienced researchers from a single institution (The University of Edinburgh). We...
Supporting Weight Management (SWiM): Evaluating the effectiveness, equity and cost-effectiveness of using acceptance-based guided self-help to improve long term outcomes of weight management interventions
Background Clinically meaningful weight loss can be achieved cost-effectively through behavioural, pharmacological and surgical approaches and can reduce incidence and complicatio...
NIHR Manchester University NHS Foundation Trust UKCRF
The UK Clinical Research Facility Network (UKCRFN) connects CRFs (NIHR and non-NIHR) to benefit patients across the UK/Ireland. By sharing expertise and resources, delivering netwo...
Mechanistic trial of problem solving and behavioural activation for youth depression
This proposal aims to advance understanding about the effectiveness and mechanisms of problem solving (PS) and behavioural activation (BA) as early interventions for youth depressi...
The ROSIER Trial: Requirement For Surgical Intervention After ERCP
Research question: Is expectant management (EM) non-inferior and cost-effective compared to laparoscopic cholecystectomy (LC) in patients with common bile duct (CBD) stones followi...
The neoGASTRIC trial: Avoiding routine gastric residual volume measurement in neonatal critical care, a multi-centre, randomised controlled trial
RESEARCH QUESTION: In preterm infants (Population), does not routinely measuring gastric residual volumes (Intervention), compared with routine up to 6 hourly measurement of gastri...
A novel reliever strategy for children with asthma: CARE-UK: Children’s Anti-Inflammatory Reliever Study
Research question In children aged 4 to 11 years with asthma, is a combination budesonide-formoterol reliever inhaler either used alone or as both maintenance and reliever treatme...
SOcial Care Rapid evAluation TEam (SOCRATES)
Background There is an urgent need to improve social care for adults, children and families. Decision-makers need to know which innovations and service developments are promising...
H2FlyGHT (Hybrid Hydrogen Flying cryoGenic tecHnology demonstraTor)
H2FlyGHT is a strategic industrial research programme as part of an international flight demonstration programme led by Embraer with an objective to develop and test a fully integr...
Exacerbation Prevention in COPD-OSA overlap syndrome (EPiC-OSA)
Introduction: Exacerbations of chronic obstructive pulmonary disease (COPD) are a major burden to the health system and cause significant morbidity for patients. Patients with COP...