Browse All Grants
44,293 grants found
Showing 181 – 200 of 44,293 grants
NIHR Group on Environmentally Sustainable Hospitals in Low and Middle Income Countries
RESEARCH QUESTION To co-develop and test interventions to decarbonise operating theatres and hospitals in low and middle income countries. BACKGROUND Climate change is an eme...
Curing genetic heart muscle disease (CureHeart)
Cardiomyopathies are among the most common severe genetic diseases, occurring with a prevalence of 1 in 250 across all populations. They are the leading cause of sudden death in th...
Translating GLP Compatible Immunomodulatory and Pro-regenerative Particles To Promote The Function Of Islets Following Transplantation In Humans.
Islet transplantation into the liver of someone with Type 1 diabetes stabilises blood glucose control but rarely results in insulin independence, as most islets are destroyed post-...
Investigating the clinical and cost-effectiveness of a nutrient enriched diet for babies with a brain injury: The DOLFIN Randomised controlled trial
Research question In babies born very pre-term or with less oxygen around the time of birth (participants), does nutritional fortification with DHA, choline and uridine-5-monophos...
Time-restricted eating as an adjunctive intervention for bipolar disorder
Extensive research indicates that sleep and biological rhythms are often disrupted among those with bipolar disorder (BD) and among their relatives, and that these biological rhyth...
Virus Genomics for Outbreak Response (ViGOR) in Central/East Africa
Identifying effective and proportionate public health control measures for infectious disease outbreaks relies on detailed data about the pathogen, its distribution, and its transm...
Rapid Service Evaluation Team (RSET)
BACKGROUND Service or policy innovations to improve health and social care practice may be introduced rapidly, often without robust evidence. AIMS To address this, RSET will...
Strengthening Mental Health Science II
WHO proposes to strengthen mental health science relevant to its mission by developing: (1) A Flexible Diagnostic Interview tool (FLII-11) for ICD-11. Existing tools are restricted...
National facility for ultra-high field (11.7T) human MRI scanning
The need for increased sensitivity and contrast drives the development of magnetic resonance imaging towards increasing magnetic field strength, with the most recent step being fro...
Oral bacterial lysate to prevent persistent wheeze in infants after severe bronchiolitis; a randomised placebo controlled trial (BLIPA; Bacterial Lysate in Preventing Asthma)
Research question In infants hospitalised with bronchiolitis, does oral Broncho Vaxom (BV; a lysate of respiratory bacteria), given for 10 days per month for a total of 24 months,...
A Randomised Phase III Trial Comparing Intermittent with Continuous Treatment Strategies in chronic lymphocytic leukaemia (CLL)
Design A prospective, multicentre, open-label, randomised, controlled, 2-arm, parallel-group, non-inferiority study to comparing an intermittent treatment strategy (experimental a...
Using rTMS to enhance social cognition in people with psychosis
In people with psychosis, deficits in social cognition are responsible for a large proportion of the functional disability associated with illness. In a previous study, we found th...
AIR SAFETY. A programme to prevent aerosol borne respiratory diseases using Artificial Intelligence
Scientific Abstract (499 words, max allowed 500 words) Research question How to enable simple user-introduced mitigations to reduce hospital airborne disease transmission by imp...
Mixed methods co-design and evaluation of a Decision Support Tool to enable shared decision making for people who are considering cascade screening for Thoracic Aortic Disease: The DECIDE TAD Programme.
Research Question: Will implementation of a Decision Support Tool improve detection of latent Thoracic Aortic Disease (TAD) through increased uptake of cascade screening in people...
ACCLIMATISE: Attribution of a Changing CLIMate in the AssessmenT of malaria Intervention Strategy Efficiency
Recent significant investments in malaria interventions have reduced malaria burden. Contemporaneously, the climate has continued to warm with associated changes in rainfall and we...
Improving Equity in Respiratory Disease Outcomes in Africa using Data-Driven Tools: EQUI-RESP-AFRICA
Aims. An interdisciplinary group of academics, policymakers, representatives of non-governmental organisations (NGOs), patients and civil society will implement a 4-year programme...
Engineering prosurvival synthetic microenvironments by modulating extrinsic and intrinsic factors in stem cell-derived islet-cells
The use of human pluripotent stem cell (SC)-derived islets holds promise as a therapy for Type 1 diabetes (T1D), but the lack of suitable conditions sustaining cell survival after...
NIHR Biomedical Research Centre at The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research
Background Every day in the UK, over 1,000 people of all ages are diagnosed with cancer. More than half will die from this devastating disease. Many survive with long-term effects...
The Mary Lyon Centre, the national MRC facility for mouse genetics
The Mary Lyon Centre at MRC Harwell (MLC) is the UK’s national facility for mouse genetics and the use of mouse models for the study of human disease. The specialised services avai...
Early Vasopressors in Sepsis (EVIS)
Population: Adults presenting to an ED, AMU or SAU with signs or symptoms of community acquired sepsis and a SBP < 90 mmHg or MAP < 65mmHg and a venous lactate of > 2mmol/l Interv...