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15,626 grants found
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BNST Illuminated: Identifying and Manipulating Neuronal Circuits in Anorexia and Aversion
The inflammation-sensitive anterolateral bed nucleus of the stria terminalis (BNST), known for its involvement in negative affective states, has recently been shown to tap into can...
The “Göteborg-2 trial”; A prospective, randomized, population-based trial of prostate cancer screening with PSA testing followed by MRI of the prostate.
This is a continued application of the Göteborg 1 and 2 prostate cancer (PC) screening trials. The main aim is to develop a better screening algorithm that improves the ratio of ha...
No(w)stalgia of Modernity: Neo-Soviet Myth in Contemporary Russian Culture and Politics
The recent decade of Russian history is often described as an ideological turn characterized by a new wave of revisionism, the revival of Soviet political and cultural mechanisms a...
Translating genomic discoveries into improved clinical decision making, mechanistic understanding, and therapy of acute leukemia
The overall objectives of this proposal are to improve clinical decision making of acute leukemia by using integrative genomic sequencing approaches, to increase our understanding...
Obesity and androgen excess in women; Adiponectin as a new treatment for metabolic, reproductive and mood disorders
Obese women with and without polycystic ovary syndrome (PCOS) display high circulating androgen and low adiponectin levels during pregnancy, which affect the fetus and may increase...
School choices, residential mobility, and the (re)production of school segregation
This 4-year project examines how school segregation and residential segregation are interrelated in Sweden. More specifically, we ask how the residential choices parents make for t...
Cultures of care: Why countries in Western Europe choose different actors to counter the care crisis
European countries have reallocated care tasks to new care providers. Sweden opened the care market for for-profit actors, Germany gave a prominent role to faith-based care provide...
Two strikes to inflammation: the role for oxidative stress as an early event in the pathogenesis of psoriasis
Psoriasis is an index disease of chronic inflammatory disorders because numerous specific, but symptomatic treatments have been approved as a consequence of identifying T helper 17...
Neuronal mechanisms of postural control: physiology and pathophysiology
Control of posture and balance is a vital function of the CNS. GENERAL GOAL of this project is to understand the organization and operation of neuronal mechanisms responsible for p...
Political and distributive consequences of the de-carbonized welfare state
Many environmental policies currently being enacted to slow climate change have distributive - and thereby political implications. Policy instruments such as carbon taxes and fees...
Challenging the domestic. Gender division of labour and economic change studied through 19th century crofters’ households
This project aims to a deepened understanding of how gender have structured economic development. This will be done through studying rural households’ labour organization during th...
Targeting estrogen and adenosine receptors cross-talk for osteoarthritis treatment
The high incidence of osteoarthritis (OA) in post-menopause women suggests that estrogen decline is a possible trigger of the OA pathogenesis. The goal of the proposed project is...
Regulation of colonic stem cell proliferation: A novel role for redox signaling
Dysregulation of colon epithelial barrier integrity can lead to inflammatory bowel disease (IBD) including ulcerative colitis and Crohn´s disease. Redox biology and reactive oxygen...
Careers in the Swedish labor market from the 1960´s and onward: From stability to instability?
A common picture of today´s labor market is that careers have become more complex in contrast to the labor market of the past characterized by permanent jobs with few shifts betwee...
Nearness of family - geographic proximity and care of older people in Sweden and Europe
In times of population ageing , care and support from families is often vital and old people with weak family ties become particularly vulnerable. The aim of this project is to con...
Muslims and the Swedish model: A longitudinal study of state–Muslim civil society relations.
In Sweden relations between the state and Muslim organizations are currently subject to a confidence crisis, as the organizations are accused of not living up to basic democratic v...
Globalization, Firms and Greenhouse Gas Emissions
The increase in global temperatures is a key policy challenge of our time.In our project, we will use detailed data on firms – energy inputs, import patterns, balance sheets and wo...
Internationella standardtest för ansträngningsutlöst andfåddhet
Bakgrund: Andfåddhet är det dominerande symtomet för personer med hjärtlungsjukdom och orsakar stort lidande och begränsning av livet. Andfåddhet leder ofta till att folk minska...
Revealing cytoplasmic and nuclear activity of actin regulators during B cell diversification
It has become evident that the actin cytoskeleton functions both in the cytoplasm and nucleus. The Wiskott-Aldrich syndrome protein (WASp) family coordinate receptor signalling to...
Defining the metabolic signatures of tissue resident Innate Lymphoid Cells
Innate Lymphoid Cells (ILCs) is a recently discovered family of tissue resident lymphocytes capable of rapid responses to a broad range of inflammatory cues. Whilst present at low...