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15,626 grants found
Showing 14,441 – 14,460 of 15,626 grants
Are environmental contaminants increasing the risk of developing the autoimmune disease multiple sclerosis?
Multiple sclerosis (MS) is mainly affecting young people and women. Untreated, it leads to severe disability and premature death.The cause of MS is largely unknown, but epidemiolog...
Shifting grounds - The politics of sand in East Africa
The world’s most used solid resource, the key ingredient of urbanization and economic growth—sand—usually escapes our attention.Skyrocketing demand for sand has sparked conflict an...
Who develops the city of the future? Mapping the contested field of urban development expertise
In a rapidly urbanizing world increased attention is being paid to the development of urban environments.At the same time the array of experts who are expected to design and develo...
Sex-bias in pediatric T-cell acute lymphoblastic leukemia; towards targeted therapy and precision medicine
Pediatric T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy with a pronounced sex-bias (~71% male).Based on my striking preliminary results I hypothesize that...
Dynamics of immigrant integration in unemployment, poverty, and segregation
This project applies a life course perspective to study socioeconomic inequalities in terms of unemployment and income poverty dynamics between second generation immigrants and anc...
Smell this! - Improving enrichment materials for pigs using odours
Pigs are highly motivated for exploring.When commercially kept pigs are unable to satisfy their need for performing this behaviour, it can be detrimental for both animal welfare an...
Pathogenicity and immunity in human infections with the tick-borne bacterium "Candidatus Neoehrlichia mikurensis
Candidatus (Ca.) Neoerhlichia (N.) mikurensis is an emerging tick-borne pathogen of humans that gives rise to the infectious disease neoehrlichiosis. We have recently succeeded in...
Indicators for monitoring changes in genetic variation for conservation of biodiversity
The need to conserve genetic biodiversity is widely recognized in international and national policy, and new goals for the coming thirty years are currently in progress within the...
Molecular mechanisms of TGFbeta signaling
Our aim is to elucidate molecular mechanisms involved in TGFb signaling in breast cancer.TGFb has both tumor suppressor (inhibits growth and induces apoptosis) and tumor promoting...
The plastic pollution challenge: a global social-ecological perspective
This agenda-setting transdisciplinary project will assess knowledge-action systems that deal with the global ‘plastic pollution challenge’.The project will: examine the scope of pl...
Innovative exercise for extrapulmonary benefits in COPD: feasibility, effects & mechanisms of supramaximal high-intensity training
The aim is to determine the feasibility & effect of a novel concept of supramaximal High-Intensity Training on muscle, brain, cardiovascular, and psychological function among p...
New statistical models of tumour progression for studying factors of aggressive breast cancer, tumour heterogeneity and personalised screening
We will develop and use novel, biologically-motivated statistical models of tumor progression to identify factors of fast growing and spreading breast tumors, understand molecular...
Novel probiotic and immunotherapy approaches for infection of human skin by Staphylococcus
With the rise of antimicrobial resistance, the pursuit of novel approaches for infection treatment and control is intensifying. It has been suggested that understanding and exploit...
The long-term impact of bariatric surgery on everyday life
To date, bariatric (weight-loss) surgery is the only treatment that results in large and sustained weight loss in people with obesity. Bariatric surgery should be viewed as a lifel...
Alzheimer´s disease is a fat problem
The APOE4 allele is the strongest genetic risk factor for sporadic Alzheimer´s disease (AD). How APOE4 increases the risk of AD is despite ample research still not fully understood...
Explore how cells send RNAs to each other via exosomes and how to utilize this process for therapeutic purposes
Background: Extracellular vesicles (EVs) are a heterogeneous population of nano- and micro-sized vesicles, including microvesicles and exosomes that are secreted by almost every ce...
Chronic kidney disease as a clinical model to identify novel approaches to prevent early vascular ageing
Background: Cardiovascular disease (CVD) is the leading global cause of death, intimately associated with burden of lifestyle diseases that accumulate with age among the general po...
AI-driven circular business model innovation for sustainable industrial ecosystems
Swedish industry is increasingly shaped by circular economy and the rise of artificial intelligence (AI), resulting in significant transformation challenges in how industrial firms...
Physical training program for better survivorship after oesophageal cancer surgery
Background: The treatment for oesophageal cancer relies on very extensive surgery, which is usually followed by slow and incomplete recovery.Loss of muscle strength and muscle mass...
Bringing the lab to the forest: rapid and portable tools for disease diagnostics and resistance screening in Scots pine
Scots pine in Swedish forests is increasingly threatened by the accidental introductions of non-native diseases. Foresters and governmental agencies are urgently seeking knowledge...