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15,626 grants found
Showing 14,221 – 14,240 of 15,626 grants
A paleoclimate perspective on recent European summer heatwaves and droughts
The intensity and frequency of heatwaves and droughts are projected to increase in response to global warming. However, extreme European heatwaves like 2003, 2010, 2015 or 2018 exc...
Regulation of platelet activation by agonist concentration gradient-dependent inhibition
Platelets are central to thrombus formation, which is pivotal in myocardial infarction and stroke. Therefore, inhibition of undue platelet activation is vital for the treatment. Cu...
Genetic and early-life determinants of premenstrual disorders
Premenstrual disorders (PMDs), including premenstrual syndrome and premenstrual dysphoric disorder, affect millions of women globally and have a profound impact on the woman’s qual...
Mobilization and redox-cycling of uranium in two boreal sulfidic landscapes: the impacts of Fe-S mineralization pathways and wet-dry cycles
Oxidative weathering of acid sulfate soil and black shale occurs in many places worldwide and releases large quantities of acidity and highly toxic uranium into surrounding environ...
Rational use of agricultural biodiversity by reducing the need for breeding
Context: Major resistance (R) genes to plant pathogens are an important resource to create healthy crops and reduce the use of pesticides. R genes are extracted from the agricultur...
Development of novel protein-based biomaterials for sustainable water purification from heavy metals
Limited natural resources and the need of clean water demand new innovative materials and technologies, which are affordable, sustainable and resilient. This project aims to develo...
POTASSIUM CHANNEL OPENERS AS AN HYPEREXCITABILITY-REDUCING STRATEGY
Diseases depending on increased electrical excitability, such as epilepsy, pain and cardiac arrhythmia, cause decreased quality of life for the individuals and an enormous burden t...
Viral infection as an underlying cause of preeclampsia
Preeclampsia is a severe, potentially fatal pregnancy complication affecting millions of women every year. The condition is characterized by de-novo hypertension and proteinuria, b...
Green and sustainable approach to valorise high saline and oily fish processing effluents for production of nutraceuticals (INVENTION)
Fish processing industry wastewaters has been one of the problems having a very significant impact on the environment and in particular have become an issue of public concern. The...
Olfactory function, cognitive aging, and dementia
With an aging population, an increasing number of older individuals stands at risk of developing dementia and Alzheimer’s disease. This raises the need for reliable, inexpensive, a...
Tracing evolutionary routes to treatment resistance in childhood cancer across time and space
Rationale: Most children dying from cancer in the modern world do so because of widespread treatment-resistant disease. The mechanisms underlying resistance are largely unexplored...
On the road to a bio-based economy: Governance pathways and policy design for sustainable forest use (GOVFORBIO)
To reach the Sustainable Development Goals, it is central to maintain economic growth while effectively dealing with environmental problems. The transition towards a bioeconomy has...
Effects of rail traffic noise and vibration on cardiometabolic health: social inequalities in exposure, social susceptibility or both? The EpiVib-equality project
This project aims to assess whether and how rail traffic noise and vibration can contribute to socioeconomic inequalities in cardiometabolic health in Sweden. These cardiometabolic...
Metabolic performance in piglets - What does sperm small RNA have to do with it?
Offspring health and performance depend on optimal growth during embryogenesis, where uterine capacity and litter size are known limiting factors. In rodents, paternal non-genetic...
Does occupational and environmental exposure to particulate air pollution contribute to chronic kidney disease?
Some studies report an association between ambient particulate matter (PM) air pollution and the risk of Chronic Kidney Disease (CKD), defined by estimated GFR (eGFR), which is how...
Trajectories of vulnerability: A spatial perspective
The purpose of the project is to study, from a life course trajectory perspective, how vulnerable groups are affected by spatial segregation. It can be argued that a society is nev...
The marine biotechnology industry and equitable governance of marine genetic resources
The marine biotechnology sector is a pillar of the Blue Economy, and has generated anti-cancer drugs, nutraceuticals, cosmetics, and enzymes for industrial and biomedical applicati...
Decoding motor neuron resilience, vulnerability, regeneration and communication in amyotrophic lateral sclerosis to develop neuroprotective therapeutic strategies
Amyotrophic lateral sclerosis (ALS) is defined by the loss of motor neurons (MNs) that innervate voluntary muscles, leading to paralysis. MNs follow a dying-back pattern in ALS wit...
Mixing medicines: uncovering impacts of pharmaceutical pollutant mixtures on wildlife
Release of novel synthetic chemicals into the environment is amongst the fastest-growing agents of global change. This includes biologically active pharmaceuticals (e.g. antibiotic...
Preparedness against emerging mosquito-borne viral threats
Vector-borne infections are spreading north in Europe. West Nile virus and Usutu are knocking on the door. To determine the risk for introduction of mosquito borne zoonotic avian v...