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99,167 grants found
Showing 98,901 – 98,920 of 99,167 grants
Features of Broad T Cell Coronavirus Immunity
Project 2 Summary Coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 coronavirus, has quickly become a global health crisis of epic proportion. This pandemic, along wi...
Integrative Immunogen Design and Testing
Project 3 Summary Coronaviruses will likely remain a persistent threat to human health. However, whether the next significant disease outbreak will be caused by a known coronavir...
Administration Core
PROJECT SUMMARY/ABSTRACT ? Administrative Core The Administrative Core of the Berghia Brain Project will support multi-disciplinary research, aid in the dissemination of research f...
Core A- Administrative Core
Abstract Core A will provide the administrative support for the Program Project and thus serves all three Projects and the other two Cores. Specifically, the core will provide th...
CORE B- Animal Models and Tissue Analysis
Project Summary The primary goal of this Program Project is to understand the molecular mechanisms by which the physiological and pathophysiological functions of integrins are re...
CORE C- Protein Expression and Purification
Project Summary/Abstract The proposed Animal Models and Tissue Analysis Core (Core C) is an essential component to the goals of this PPG. To support the research strategies and...
Project 1- Role of Kindlins in Blood and Vascular Cell Biology
Project Summary Kindlin-2 (K2) is the most broadly distributed of the three mammalian kindlins. It is present in fibrobasts, chondrocytes, and cardiomocytes, and its global knock...
Project 2- Mechanistic Role of Talin in Cellular Signaling
Project Summary The long-term objective of this proposal is to understand the activation and signaling mechanisms of integrins – a class of heterodimeric transmembrane receptors...
Project 3- Role of Leukocyte-Platelet Interactions in Inflammation and Thrombosis
PROJECT SUMMARY/ABSTRACT This translational project will focus on systemic lupus erythematosus (SLE) as a unique disease model of inflammation and thrombosis. SLE is a complex a...
Administrative Core
Project Summary/Abstract – Administrative Core In an effort to address fundamental questions regarding the dynamics and drivers of influenza transmission between humans, the Admi...
Clinical and Biostatistics Core
Project Summary/Abstract – Clinical and Biostatistics Core The Clinical and Biostatistics Core (CBC) is a central component of the Evaluating Modes of Influenza Transmission (EMI...
Advanced Bioaerosols Technology Core
Project Summary/Abstract – Advanced Bioaerosol Technology Core The Advanced Bioaerosol Technology Core (ABTC) will develop a comprehensive suite of innovative technologies for im...
Evaluating Modes of Influenza Transmission using a Randomized Controlled Trial (EMIT-2-RCT)
Project Summary/Abstract – Evaluating Modes of Influenza Transmission using a Randomized Controlled Trial The “Evaluating Modes of Influenza Transmission using a Randomized Contr...
Developing and Applying Analytical Models of Influenza Transmission
Our current scientific knowledge indicates the importance of influenza transmission via exhaled viral bioaerosols over short and long ranges in indoor environments. The turbulent...
Center Administrative Core
Administrative Core ABSTRACT The Administrative Core supports the goals of the Collaborative Center to Develop Improved Diagnostic and Therapeutic Approaches to Endometriosis of...
Diagnosis and Treatment of Endometriosis: A Translational Approach
Project 1 (Young) Diagnosis and Treatment of Endometriosis: A Translational Approach ABSTRACT The Collaborative Center to Develop Improved Diagnostic and Therapeutic Approaches t...
SIRT1 as a Therapeutic Target in Endometriosis
Project 2: SIRT1 as a Therapeutic Target in Endometriosis ABSTRACT Progesterone resistance is now recognized as a key element in the pathophysiology of endometriosis, though its...
Imaging and treatment of endometriosis in nonhuman primates
Project 3: Imaging and treatment of endometriosis in nonhuman primates SUMMARY/ABSTRACT The overarching goal of this P01 Center is to advance our understanding of the pathophysio...
Endometriosis Education Outreach
Endometriosis Education Outreach ABSTRACT Dysmenorrhea, painful periods, is the most common cause of absenteeism in young women. Endometriosis is the leading etiology; however,...
Comparative Genomics and Bioinformatics Core
Comparative Genomics And Bioinformatics Core SUMMARY/ABSTRACT The Comparative Genomics and Bioinformatics (CGB) Core will provide state-of-the-art comparative genomic and bioinf...