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Showing 98,86198,880 of 99,167 grants

Active NON-SBIR/STTR RPGS
Clinical and Biostatistics Core
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Maryland, College Park United States 2021 – 2026

Project Summary/Abstract ? Clinical and Biostatistics Core The Clinical and Biostatistics Core (CBC) is a central component of the Evaluating Modes of Influenza Transmission (EMIT-...

Active NON-SBIR/STTR RPGS
Advanced Bioaerosols Technology Core
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Maryland, College Park United States 2021 – 2026

Project Summary/Abstract ? Advanced Bioaerosol Technology Core The Advanced Bioaerosol Technology Core (ABTC) will develop a comprehensive suite of innovative technologies for impr...

Active NON-SBIR/STTR RPGS
Evaluating Modes of Influenza Transmission using a Randomized Controlled Trial (EMIT-2-RCT)
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Maryland, College Park United States 2021 – 2026

Project Summary/Abstract ? Evaluating Modes of Influenza Transmission using a Randomized Controlled Trial The ?Evaluating Modes of Influenza Transmission using a Randomized Control...

Active NON-SBIR/STTR RPGS
Developing and Applying Analytical Models of Influenza Transmission
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Maryland, College Park United States 2021 – 2026

Our current scientific knowledge indicates the importance of influenza transmission via exhaled viral bioaerosols over short and long ranges in indoor environments. The turbulent n...

Completed NON-SBIR/STTR RPGS
WOOP VA: Mental Contrasting With Implementation Intentions to Promote Weight Management in Primary Care
Veterans Affairs Va Medical Center United States 2021 – 2025

Background: Approximately 40% of Veterans have obesity. Intensive weight management programs such as MOVE! promote clinically significant weight loss, but only 3-7% of eligible Vet...

Active NON-SBIR/STTR RPGS
Project 3- Role of Leukocyte-Platelet Interactions in Inflammation and Thrombosis
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Cleveland Clinic Lerner Com-Cwru United States 2021 – 2026

PROJECT SUMMARY/ABSTRACT This translational project will focus on systemic lupus erythematosus (SLE) as a unique disease model of inflammation and thrombosis. SLE is a complex aut...

Active NON-SBIR/STTR RPGS
Administrative Core
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Maryland, College Park United States 2021 – 2026

Project Summary/Abstract ? Administrative Core In an effort to address fundamental questions regarding the dynamics and drivers of influenza transmission between humans, the Admini...

Active NON-SBIR/STTR RPGS
Core A- Administrative Core
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Cleveland Clinic Lerner Com-Cwru United States 2021 – 2026

Abstract Core A will provide the administrative support for the Program Project and thus serves all three Projects and the other two Cores. Specifically, the core will provide the...

Active NON-SBIR/STTR RPGS
CORE B- Animal Models and Tissue Analysis
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Cleveland Clinic Lerner Com-Cwru United States 2021 – 2026

Project Summary The primary goal of this Program Project is to understand the molecular mechanisms by which the physiological and pathophysiological functions of integrins are regu...

Active NON-SBIR/STTR RPGS
CORE C- Protein Expression and Purification
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Cleveland Clinic Lerner Com-Cwru United States 2021 – 2026

Project Summary/Abstract The proposed Animal Models and Tissue Analysis Core (Core C) is an essential component to the goals of this PPG. To support the research strategies and su...

Active NON-SBIR/STTR RPGS
Project 1- Role of Kindlins in Blood and Vascular Cell Biology
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Cleveland Clinic Lerner Com-Cwru United States 2021 – 2026

Project Summary Kindlin-2 (K2) is the most broadly distributed of the three mammalian kindlins. It is present in fibrobasts, chondrocytes, and cardiomocytes, and its global knockou...

Active NON-SBIR/STTR RPGS
Project 2- Mechanistic Role of Talin in Cellular Signaling
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Cleveland Clinic Lerner Com-Cwru United States 2021 – 2026

Project Summary The long-term objective of this proposal is to understand the activation and signaling mechanisms of integrins ? a class of heterodimeric transmembrane receptors th...

Active NON-SBIR/STTR RPGS
Administrative Core
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Harvard School of Public Health United States 2021 – 2026

Project Summary/Abstract, Administrative Core (Core A) The proposed program project aims to close research gaps in antiretroviral treatment for pregnant women and infants living...

Active NON-SBIR/STTR RPGS
Data Management and Distribution Core
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Harvard School of Public Health United States 2021 – 2026

Project Summary/Abstract, Data Management and Distribution Core (Core B) The proposed program project aims to close research gaps in antiretroviral treatment for pregnant women an...

Active NON-SBIR/STTR RPGS
Tsepamo Plus: Expanded Congenital Abnormalities Surveillance with an Emulated Clinical Trial to Evaluate Weight Impact on Birth Outcomes for Newer ART Regimens
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Harvard School of Public Health United States 2021 – 2026

Project Summary/Abstract, Tsepamo Plus (Project 1) Antiretroviral treatment (ART) guidelines depend upon safety and efficacy data in pregnancy, especially in resource-limited set...

Active NON-SBIR/STTR RPGS
Methodology: Developing Reporting Criteria for Pregnancy Surveillance Cohorts and New Techniques for Supporting Target Trials
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Harvard School of Public Health United States 2021 – 2026

The Tsepamo birth outcomes surveillance study has accrued many thousands of women living with HIV from Botswana. The Tsepamo Plus study (Project 1) will continue to collect ARV ex...

Active NON-SBIR/STTR RPGS
Point-of-Care HIV Testing and Early Dolutegravir Use for Infants
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Harvard School of Public Health United States 2021 – 2026

Project Summary/Abstract, Point-of-Care HIV Testing and Early Dolutegravir Use for Infants (Project 3) The stakes of delaying HIV diagnosis and treatment in infancy are high. Inf...

Active NON-SBIR/STTR RPGS
Pioneering Precision Medicine Approaches for Immune Control of Pediatric HIV-1 Infection
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Harvard School of Public Health United States 2021 – 2026

Project Summary/Abstract, Immune Control (Project 4) Finding a cure for HIV-1 infection is of particular importance for the growing number of HIV-1-infected infants, children and...

Active NON-SBIR/STTR RPGS
IMPACT Project 1 – The impact of standing orders support on HPV vaccine communication and uptake
NATIONAL CANCER INSTITUTE University of North Carolina Chapel Hill United States 2021 – 2026

ABSTRACT ? Project 1 An ongoing and pressing cancer prevention challenge in the US is low HPV vaccine coverage, due in part to infrequent and low-quality provider recommendations....

Active NON-SBIR/STTR RPGS
IMPACT Project 2 – The impact of clinic-level financial incentives on HPV vaccine communication and uptake
NATIONAL CANCER INSTITUTE University of North Carolina Chapel Hill United States 2021 – 2026

ABSTRACT ? Project 2 Human papillomavirus (HPV) vaccination is effective and recommended to protect against six types of cancer, but HPV vaccine coverage remains low. Provider com...