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Showing 98,82198,840 of 99,167 grants

Completed NON-SBIR/STTR RPGS
Development and Testing of a Mobile Application to Enhance HIV Prevention Cascade in Malaysian MSM
FOGARTY INTERNATIONAL CENTER University of Connecticut Storrs United States 2021 – 2022

Abstract Malaysia?s HIV epidemic is rapidly expanding with recent evidence suggesting accelerated sexual transmission, especially in MSM: 10% in 2008 to 54% in 2016. Evidence sugge...

$1.96M
USD
Completed NON-SBIR/STTR RPGS
Developing deep learning algorithms for studying infant brain and behavior relationships
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Stanford University United States 2021 – 2021

Project Summary Infants communicate to their caregivers that they need food by crying.This represents our very first social interaction that lays the foundation for a healthy life...

$865.5K
USD
Completed NON-SBIR/STTR RPGS
Wastewater Detection of COVID-19
NATIONAL INSTITUTE ON DRUG ABUSE Missouri State Dept/ Health & Senior Srv United States 2021 – 2022

When faced with a pandemic such as SARS-Coronavirus-2 (SAR-CoV-2), the virus responsible for COVID-19, timely risk assessment and action are required to prevent public health impac...

$20M
USD
Completed NON-SBIR/STTR RPGS
Improved scalability, sensitivity, and interpretability of pathogen detection, including SARS-CoV-2, in wastewater using high-throughput, highly multiplexed digital array PCR technology
NATIONAL INSTITUTE ON DRUG ABUSE University of North Carolina Chapel Hill United States 2021 – 2022

PROJECT ABSTRACT Presently, the application of molecular technology such as RT-qPCR and digital PCR (dPCR) to quantify SARS-CoV-2 and related targets in wastewater is cumbersome, t...

$9.98M
USD
Completed NON-SBIR/STTR RPGS
Wastewater Assessment for Coronavirus in Kentucky: Implementing Enhanced Surveillance Technology
NATIONAL INSTITUTE ON DRUG ABUSE University of Kentucky United States 2021 – 2022

Wastewater Assessment for Coronavirus in Kentucky ?Implementing Enhanced Surveillance Technology Surveillance for SARS-CoV-2 is hindered by the availability of testing, particularl...

$18.34M
USD
Completed NON-SBIR/STTR RPGS
The Influence of HPV on Preterm Birth via Immunomodulation of the Microbiome
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Virginia Commonwealth University United States 2021 – 2022

Summary: This diversity supplement relates to aims 2 and 3 of the parent grant and proposes to examine the influence of (high and low) Human Papilloma Virus (HPV) on the risk of pr...

$2.21M
USD
Completed NON-SBIR/STTR RPGS
Development and Proof-of-Concept Implementation of the South Florida Miami RADx-rad SARS-CoV-2 Wastewater-Based Surveillance Infrastructure
NATIONAL INSTITUTE ON DRUG ABUSE University of Miami Coral Gables United States 2021 – 2022

PROJECT SUMMARY The University of Miami (UM), with three primary campuses in Miami, Florida, is geographically spread within one of the worst current COVID-19 hotbeds.UM has deploy...

$26.77M
USD
Completed NON-SBIR/STTR RPGS
Optimizing SARS-CoV-2 wastewater based surveillance in urban and university campus settings.
NATIONAL INSTITUTE ON DRUG ABUSE Columbia University Health Sciences United States 2021 – 2022

The novel coronavirus SARS-CoV-2 is causing significant morbidity and mortality.Current approaches to SARS- CoV-2 testing are costly, inconsistently implemented, and fail to rapidl...

$24.48M
USD
Completed NON-SBIR/STTR RPGS
The Family Input for Quality and Safety (FIQS) Study
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... University of California, San Francisco United States 2021 – 2021

Abstract Adverse patient safety event rates remain stubbornly high in hospitals. For children, adverse events are 1.5-2 times more common than in adult inpatients (40.0 vs. 25.1 ha...

$899.6K
USD
Completed NON-SBIR/STTR RPGS
Wastewater Analysis of SARS CoV-2 in Tribal Communities
NATIONAL INSTITUTE ON DRUG ABUSE Arizona State University-Tempe Campus United States 2021 – 2023

ABSTRACT The rapid onset of the COVID-19 pandemic left many across the world unprepared to test, treat, and plan for coronavirus morbidity and mortality.This was true for Tribal na...

$14.95M
USD
Completed NON-SBIR/STTR RPGS
Implementing and Sustaining a Transdiagnostic Sleep and Circadian Treatment to Improve Severe Mental Illness Outcomes in Community Mental Health.
NATIONAL INSTITUTE OF MENTAL HEALTH University of California Berkeley United States 2021 – 2022

Abstract of Diversity Supplement Recent efforts have successfully trained providers to deliver evidence-based treatments (EBTs) in community mental health centers (CMHCs); however,...

$629.1K
USD
Completed NON-SBIR/STTR RPGS
Diagnosing and predicting risk in children with SARS-CoV-2- related illness
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... University of California, San Diego United States 2021 – 2022

In the wake of COVID-19 pandemic, Multisystem Inflammatory Syndrome in Children (MIS-C) has evolved as a new threat to children exposed to SARS-CoV-2.The emergence of MIS-C is so n...

$6.98M
USD
Completed NON-SBIR/STTR RPGS
A data science approach to identify and manage Multisystem Inflammatory Syndrome in Children (MIS-C) associated with SARS-CoV-2 infection and Kawasaki disease in pediatric patients
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Johns Hopkins University United States 2021 – 2022

Summary ?Since the SARS-CoV-2 pandemic began, the emergence of an associated novel multisystem inflammatory syndrome in children (MIS-C) has been reported.Interestingly, patients w...

$9.18M
USD
Completed NON-SBIR/STTR RPGS
AICORE-kids: Artificial Intelligence COVID-19 Risk AssEssment for kids
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Baylor College of Medicine United States 2021 – 2022

This work is directed at characterizing pediatric COVID-19 and stratifying incoming patients by projected (future) disease severity.Such stratification has several implications: im...

$8.18M
USD
Completed NON-SBIR/STTR RPGS
Diagnosis of MIS-C in febrile children
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Children'S Hosp of Philadelphia United States 2021 – 2022

PROJECT SUMMARY The recent emergence of SARS-CoV-2 and resultant pandemic of COVID-19 disease has overwhelmed global health systems and led to over 200,000 American deaths to date....

$8.79M
USD
Completed NON-SBIR/STTR RPGS
Severity Predictors Integrating salivary Transcriptomics and proteomics with Multi neural network Intelligence in SARS-CoV2 infection in Children (SPITS MISC)
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Central Michigan University United States 2021 – 2022

Abstract Children have been disproportionately less impacted by the Corona Virus Disease 2019 (COVID-19) caused by the Severe Acute Respiratory Syndrome Corona Virus 2 (SAR-CoV-2)...

$7.35M
USD
Completed NON-SBIR/STTR RPGS
The Role of Altered Luminal Dynamics in OSA-Induced Atherosclerosis
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE University of California, San Diego United States 2021 – 2023

ABSTRACT The prevalence of obstructive sleep apnea (OSA) has been estimated to be 34% for men and 17% for women between 30 and 70-years old, but is far more common among patients w...

$626.2K
USD
Completed NON-SBIR/STTR RPGS
Identifying biomarker signatures of prognostic value for Multisystem Inflammatory Syndrome in Children (MIS-C)
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Connecticut Children'S Medical Center United States 2021 – 2022

PROJECT SUMMARY / ABSTRACT In adults, SARS-CoV-2 infection exhibits a wide range of clinical outcomes, from asymptomatic and mild disease to severe viral pneumonia, respiratory dis...

$8.78M
USD
Completed NON-SBIR/STTR RPGS
Discovery and clinical validation of host biomarkers of disease severity and multi-system inflammatory syndrome in children (MIS-C) with Covid-19
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... University of California, San Francisco United States 2021 – 2022

ABSTRACT Novel approaches for early and accurate diagnosis of COVID-19 associated syndromes and evaluation of clinical severity and outcomes of COVID-19 disease in children are urg...

$8.64M
USD
Completed NON-SBIR/STTR RPGS
COVID-19 Network of Networks Expanding Clinical and Translational approaches to Predict Severe Illness in Children (CONNECT to Predict SIck Children)
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Rbhs-Robert Wood Johnson Medical School United States 2021 – 2022

The SARS-CoV-2 pandemic has manifested in children with a wide spectrum of clinical presentations ranging from asymptomatic infection to devastating acute respiratory symptoms, app...

$8.4M
USD