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99,167 grants found
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A sequential, adaptive model of differentiated service delivery to reach persons living with HIV who are lost-to-follow-up or who have detectable viral load
ABSTRACT Globally, more than half of the world's 37 million people living with HIV are on antiretroviral therapy (ART) representing immense and encouraging success with access...
Traditional healer-initiated HIV counseling and testing in rural South Africa
Project Summary In South Africa, HIV testing has been undermined by HIV stigma, distrust in the allopathic health system, a preference for traditional medicine, and distance to the...
SCH: Advancing Language-based Analyses of Social Media to Reliably Monitor Variation in Population
This proposal seeks to address a key challenge in public health : the ongoing and fine-grained measurement of population mental health.Currently, in the largest population surveys,...
Rapid Understanding of Best Practices in Rural Intensive Care (RUBRIC)
PROJECT SUMMARY/ABSTRACT Background: Nearly 15% of Americans live in rural communities, but only 1% of intensive care unit (ICU) beds are located in those same communities. The COV...
Chronic Lung Disease and COVID-19: Understanding Severity, Recovery and Rehabilitation Needs (LAUREL Study)
SARS-CoV-2 (SARS2) infection, which leads to COVID-19, is a global pandemic.Chronic lung disease (CLD), particularly chronic obstructive pulmonary disease (COPD), has emerged as a...
Quality, Safety, Value: Impact of sudden shift to telehealth due to COVID-19 within Nurse-led care models located in Colorado rural and urban communities
Quality, Safety, Value: Impact of Sudden shift to Telehealth due to COVID-19 within Nurse-led care Models located in Colorado Rural and Urban Communities Project Summary COVID-19 h...
Responses of the Program of All-Inclusive Care of the Elderly (PACE) Organizations to COVID-19 Challenges: Effects and Lessons Learned
Project Summary/Abstract.PACE (the Program of All-Inclusive Care for the Elderly) is a well-known and respected financing and care delivery model for a very challenging population:...
Infection Control Measures in Dialysis Facilities after COVID-19: Disparities in Adoption and Impact on Hospitalization and Mortality
PROJECT SUMMARY The COVID-19 pandemic threatens the health of patients with kidney failure because end-stage kidney disease (ESKD) is a risk factor for COVID-19 related death.Most...
Leveraging Health System Telehealth and Informatics Infrastructure to Create a Continuum of Services for COVID-19 Screening, Testing, and Treatment: A Learning Health System Approach
PROJECT SUMMARY/ABSTRACT The COVID-19 pandemic reached the US with little warning, and thus caught both public health and medical care delivery systems inadequately prepared to cop...
A Multi-Site Evaluation of Primary Care Accessibility and Utilization during COVID-19
ABSTRACT The objective of the proposed research is to evaluate how patient access and utilization of primary care was disrupted by COVID-19 across three healthcare systems, with a...
Evaluating and Enhancing Health Information Technology for COVID-19 Response Workflow in a Specialized COVID-19 in a Medically Underserved Community
Project Summary/Abstract The COVID-19 pandemic has exposed vulnerabilities across the United States healthcare system and provided a serious test of hospitals? resilience.The syste...
Care and Safety Practices during the COVID-19 Pandemic in Home-Based Long term Services and Supports
Project Abstract Older adults and individuals with disabilities prefer to receive Long Term Services and Supports (LTSS) in their home, which may be safer than congregate care sett...
GS-441524 is Pharmacodynamically Equivalent to Remdesivir and Pharmacokinetically Superior Drug for the Treatment of COVID-19
ABSTRACT. Covid-19 is a once in a generation epidemic that has had dire, destabilizing impacts across the world.While remdesivir has emerged as the only drug with proven efficacy,...
CD25-mediated feedback control of BCR-signaling and its oncogenic mimics
PROJECT SUMMARY B cells critically depend on continuous survival and proliferation signals from a functional B cell receptor (BCR). Likewise, in ~50% of B cell malignancies, the tu...
Targeting polyamines to suppress SARS-CoV-2 related disease
ABSTRACT The pandemic COronaVIrus disease 2019 (COVID-19) is an infectious disease, which is caused by a novel and highly pathogenic virus strain SARS-CoV-2 (Severe acute respirato...
RESHAPE Diversity Supplement
Project summary The current Diversity Supplement proposal examines the relationship between mental health diagnosis and stigma and gender, age, caste, and ethnicity given the dispa...
MicroRNA Function During Neuronal Reprogramming in Treating Spinal Cord Injury
Project Summary: One major obstacle in treating spinal cord injury (SCI) is to replenish neurons that are lost during the course of injury and to restore local neuronal circuitry f...
Efficacy of Fenofibrate for COVID-19: A phase II randomized controlled trial
PROJECT SUMMARY Aging, obesity, diabetes, hypertension and other risk factors associated with abnormal lipid and carbohydrate metabolism are risk factors for death in Coronavirus d...
IL13 - A Novel Therapeutic Factor for Cardiac Regeneration
PROJECT SUMMARY/ABSTRACT Organisms such as zebrafish and neonatal mice are capable of complete heart regeneration following partial amputation.Although adult humans and adult mice...
COVID-19 Testing and Linkage to Care with African American Church and Health Agency Partners
PROJECT SUMMARY African Americans (AA) are disproportionately burdened by COVID19 across the spectrum of related cases, hospitalizations, and deaths compared to Whites.Many multila...