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Active NON-SBIR/STTR RPGS
Resource Core 3 - Teaching/Training/Dissemination Core (TTDC)
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND S... Stanford University United States 2021 – 2026

Resource Core 3 - Teaching/Training/Dissemination Core (TTDC) Leads: Maisie Lo PhD and Kristin Overton PhD Summary The TTDC’s teaching mission specifically leverages our educa...

Active NON-SBIR/STTR RPGS
Project 1
NATIONAL CANCER INSTITUTE University of Minnesota United States 2021 – 2026

Abstract In glioblastoma (GBM), cancer cells break away from the tumor mass and infiltrate into adjacent brain tissue. Like other poor-prognosis cancers, GBM has been extensively a...

Active NON-SBIR/STTR RPGS
Project 2
NATIONAL CANCER INSTITUTE University of Minnesota United States 2021 – 2026

Pancreatic ductal adenocarcinoma is an extremely lethal disease with the lowest 1-year and 5-year survival rates of any cancer. This is due, in part, to the extremely metastatic be...

Active NON-SBIR/STTR RPGS
Project 3
NATIONAL CANCER INSTITUTE University of Minnesota United States 2021 – 2026

ABSTRACT: PROJECT 3 Over the last several decades, it has become possible to isolate a patient?s own cells, engineer and expand them in the laboratory, and use them to treat an exi...

Active NON-SBIR/STTR RPGS
Administrative Core
NATIONAL CANCER INSTITUTE University of Minnesota United States 2021 – 2026

Abstract Integrating advanced engineering tools and approaches into immunotherapy development projects holds the potential to improve the efficiency of the pre-clinical therapy dev...

Completed NON-SBIR/STTR RPGS
Administrative Core
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Brigham and Women'S Hospital United States 2021 – 2025

ADMININSTRATIVE CORE A SUMMARY To support this program, the Administrative Core A aims to administratively support the scientific activities of this group by enabling the free exch...

Completed NON-SBIR/STTR RPGS
Technology and Computational Core
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Brigham and Women'S Hospital United States 2021 – 2025

PROJECT SUMMARY CORE B The goal of this Program Project is to bring together a multi-disciplinary team to produce information necessary for the design and testing of the next-gener...

Completed NON-SBIR/STTR RPGS
Cross-Protective Humoral Immunity to Coronavirus
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Brigham and Women'S Hospital United States 2021 – 2025

PROJECT 1 SUMMARY Global establishment of Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV)-2 is a continued human threat. While successful vaccine programs are well under...

Completed NON-SBIR/STTR RPGS
Features of Broad T Cell Coronavirus Immunity
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Brigham and Women'S Hospital United States 2021 – 2025

Project 2 Summary Coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 coronavirus, has quickly become a global health crisis of epic proportion. This pandemic, along with...

Completed NON-SBIR/STTR RPGS
Integrative Immunogen Design and Testing
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Brigham and Women'S Hospital United States 2021 – 2025

Project 3 Summary Coronaviruses will likely remain a persistent threat to human health. However, whether the next significant disease outbreak will be caused by a known coronavirus...

Active NON-SBIR/STTR RPGS
Project 1
NATIONAL CANCER INSTITUTE University of Minnesota United States 2021 – 2026

Abstract In glioblastoma (GBM), cancer cells break away from the tumor mass and infiltrate into adjacent brain tissue. Like other poor-prognosis cancers, GBM has been extensively...

Active NON-SBIR/STTR RPGS
Project 2
NATIONAL CANCER INSTITUTE University of Minnesota United States 2021 – 2026

Pancreatic ductal adenocarcinoma is an extremely lethal disease with the lowest 1-year and 5-year survival rates of any cancer. This is due, in part, to the extremely metastatic b...

Active NON-SBIR/STTR RPGS
Project 3
NATIONAL CANCER INSTITUTE University of Minnesota United States 2021 – 2026

ABSTRACT: PROJECT 3 Over the last several decades, it has become possible to isolate a patient’s own cells, engineer and expand them in the laboratory, and use them to treat an e...

Active NON-SBIR/STTR RPGS
Administrative Core
NATIONAL CANCER INSTITUTE University of Minnesota United States 2021 – 2026

Abstract Integrating advanced engineering tools and approaches into immunotherapy development projects holds the potential to improve the efficiency of the pre-clinical therapy d...

Completed NON-SBIR/STTR RPGS
Administrative core
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Wisconsin-Madison United States 2021 – 2024

SUMMARY The Administrative Core of the Pan-Coronavirus Vaccine (PanCoVac) Consortium is responsible for organizing and overseeing all administrative aspects of the research progr...

Completed NON-SBIR/STTR RPGS
Design and evaluation of pan-CoV vaccines
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Wisconsin-Madison United States 2021 – 2024

SUMMARY As part of the Pan-Coronavirus Vaccine (PanCoVac) Consortium, the goal of Research Project 1 (RP1) is the ‘Design and evaluation of pan-CoV vaccines’. A comprehensive ch...

Completed NON-SBIR/STTR RPGS
Immunological responses to pan-CoV vaccines
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Wisconsin-Madison United States 2021 – 2024

Summary The pan-coronavirus vaccine (PanCoVac) consortium will develop novel coronavirus vaccines that can provide protection against a range of coronaviruses. Research Project...

Completed NON-SBIR/STTR RPGS
Core 1: Administrative Core
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Duke University United States 2021 – 2024

Administrative Core 1 Abstract The overall goal of this program project is to design and develop panbetacoronavirus (panbetaCoV) vaccines for group 2b and 2c betaCoVs that will...

Completed NON-SBIR/STTR RPGS
Core 2: Biocontainment and Immune Monitoring Core
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Duke University United States 2021 – 2024

Core 2: Biocontainment and Immune Monitoring Abstract The overall goal of this program is to develop a vaccine or vaccines that will be available when the next betaCoV outbreak...

Completed NON-SBIR/STTR RPGS
Core 3: Non-human Primate Core
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Duke University United States 2021 – 2024

Abstract - Core 3 The current SARS-CoV-2 pandemic is the third major pathogenic outbreak caused by a betaCoV in the last two decades. Development of panbetacoronavirus (panbetaCo...