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99,167 grants found
Showing 98,781 – 98,800 of 99,167 grants
Administrative Core
Not applicable to the Administrative Core.
Synthetic Biology and Optogenetics Core
Abstract The Program Project will employ in all projects novel engineered reagents that enable manipulation and interrogation of individual signaling pathways with precise spatia...
Advanced Imaging Core
Abstract Advanced Imaging Core C is essential to accurately define spatial and temporal organization of processes governing macrophage plasticity. Surface markers determined by f...
Patient Sampling and Genomics Core
PROJECT SUMMARY / ABSTRACT A critical translational component of this Program Project involves the correlative analysis of macrophages (Mφ) isolated from critically ill patients...
Ion Flux Regulation of Macrophage Plasticity in Lung Injury and Repair
PROJECT SUMMARY/ABSTRACT Macrophages (Mφ) are essential for the innate immune function of lungs. The ability of macrophages to integrate signals from microbes and the tissue nich...
CREB Programming of Alveolar Macrophage Population and Inflammatory Lung Injury
PROJECT SUMMARY/ABSTRACT The lung’s ability to recover from severe inflammatory injury depends on its capacity to rapidly mobilize intrinsic tissue repair pathways. Macrophages (...
Endothelial Instruction of Macrophage Fate in Inflammatory Lung Injury
PROJECT SUMMARY/ABSTRACT Studies have shown much broader roles for macrophages in responding to inflammation and tissue injury than previously recognized, such as promoting infla...
Administrative Core
Administrative Core (AC) Lead: Karl Deisseroth MD PhD Project Summary The Administrative Core of the U19 will 1) shoulder the complex burden of coordination and communication...
Data Science Core
Data Science Core (DSC) Leads: Krishna Shenoy PhD and Chris Roat PhD (with Surya Ganguli PhD) Project Summary Given the large volumes of optical, electrical, genetic and behavi...
Resource Core 1 - Primate/rodent Molecular Anatomy Core (PMAC)
Resource Core 1 - Primate/rodent Molecular Anatomy Core (PMAC) Leads: Kristin Overton PhD and Karl Deisseroth MD PhD Summary The PMAC will develop, validate, and implement (in...
Resource Core 2 - Primate/rodent Optics Core (POC)
Resource Core 2 - Primate/rodent Optics Core (POC) Leads: Ailey Crow PhD and Sean Quirin PhD Project Summary The Primate/rodent Optics Core (POC) involves the guided use and o...
Resource Core 3 - Teaching/Training/Dissemination Core (TTDC)
Resource Core 3 - Teaching/Training/Dissemination Core (TTDC) Leads: Maisie Lo PhD and Kristin Overton PhD Summary The TTDC’s teaching mission specifically leverages our educa...
Research Project 1 - Developing and applying tools to probe internal state dynamics of perception and motivation
Research Project 1 - Internal state dynamics of perception and motivati0n Lead: Karl Deisseroth MD PhD Summary This project is focused on development and application of technol...
Research Project 2 - Internal state dynamics of primate perception and decision-making
Research Project 2 - Internal state dynamics of primate perception and decision-making Lead: Eyal Seidemann PhD Project Summary The overarching goal of RP2 is to understand ho...
Research Project 3 - Theory and computation of internal state dynamics
Research Project 3 - Theory and computation of internal state dynamics Leads: Surya Ganguli PhD and Krishna Shenoy PhD (with David Sussillo PhD) Project Summary This research p...
Research Project 4 - Internal state dynamics of navigation and memory
Research Project 4 – Internal state dynamics of navigation and memory Lead: Lisa Giocomo PhD Project Summary In RP4 (Navigation and memory) we leverage the navigation system t...
Administrative Core
Administrative Core (AC) Lead: Karl Deisseroth MD PhD Project Summary The Administrative Core of the U19 will 1) shoulder the complex burden of coordination and communication...
Data Science Core
Data Science Core (DSC) Leads: Krishna Shenoy PhD and Chris Roat PhD (with Surya Ganguli PhD) Project Summary Given the large volumes of optical, electrical, genetic and behavi...
Resource Core 1 - Primate/rodent Molecular Anatomy Core (PMAC)
Resource Core 1 - Primate/rodent Molecular Anatomy Core (PMAC) Leads: Kristin Overton PhD and Karl Deisseroth MD PhD Summary The PMAC will develop, validate, and implement (in...
Resource Core 2 - Primate/rodent Optics Core (POC)
Resource Core 2 - Primate/rodent Optics Core (POC) Leads: Ailey Crow PhD and Sean Quirin PhD Project Summary The Primate/rodent Optics Core (POC) involves the guided use and o...