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Active NON-SBIR/STTR RPGS
METHODS AND ANALYSIS CORE
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM University of Alabama At Birmingham United States 2021 – 2026

Project Summary/Abstract Unhealthy alcohol use is a major unaddressed barrier to control of the HIV epidemic in sub-Saharan Africa and the United States. The Zambia Alabama HIV A...

Active NON-SBIR/STTR RPGS
Alcohol Research Consortium in HIV: Administrative Core
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM Johns Hopkins University United States 2021 – 2026

This program project application for the Alcohol Research Consortium on HIV (ARCH)* builds on and extends our very successful administrative and research accomplishments over the...

Active NON-SBIR/STTR RPGS
Alcohol Research Consortium in HIV: Biostatistics and Method Core
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM Johns Hopkins University United States 2021 – 2026

HIV Treatment as Prevention (TASP) is critical to Ending the HIV Epidemic (EHE). At-risk alcohol use and alcohol used disorder (AUD) are barriers to TASP through direct impacts on...

Active NON-SBIR/STTR RPGS
Administrative, Education, and Analytic Support Core
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM Vanderbilt University Medical Center United States 2021 – 2026

Alcohol consumption is an important modifiable cardiovascular disease (CVD) risk factor among people living with HIV infection (PLWH). Given that alcohol use is common among PLWH,...

Active NON-SBIR/STTR RPGS
Alcohol Research Consortium in HIV: Relapse Prevention Arm
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM Johns Hopkins University United States 2021 – 2026

At risk alcohol use and alcohol use disorders (AUD) are prevalent among people with HIV (PWH) and cause well-documented harms across the HIV prevention and care continuum. A numbe...

Active NON-SBIR/STTR RPGS
Integrated Metagenomic and Metabolomic Core
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM Vanderbilt University Medical Center United States 2021 – 2026

The Integrated Metagenomics and Metabolomics Core (IMMC) will provide a platform that interconnects Projects 1 and 2. Specifically, IMMC will provide high-quality, metagenomics an...

Active NON-SBIR/STTR RPGS
SHARE Administrative Core
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM Florida State University United States 2021 – 2026

To address research gaps in alcohol and HIV comorbidity in young people living with HIV (YPLWH), particularly in Florida, Florida State University’s SHARE Program (Self-management...

Active NON-SBIR/STTR RPGS
SHARE Data Science Core
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM Florida State University United States 2021 – 2026

DATA SCIENCE CORE ABSTRACT Alcohol use that is common among HIV-infected people adversely affects transmission of HIV, engagement and retention in care, and susceptibility to coi...

Active NON-SBIR/STTR RPGS
Community Engagement Core
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM Florida State University United States 2021 – 2026

PROJECT SUMMARY The translational science spectrum represents each stage of research: pre-clinical, clinical, and implementation science. Conducting research across the translati...

Active NON-SBIR/STTR RPGS
SMARTer Healthy Choices: Optimizing a state-wide scalable intervention to improve alcohol and HIV self-management in adolescents and emerging adults (Project SUSTAIN)
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM Florida State University United States 2021 – 2026

SUSTAIN ABSTRACT Despite decades of research on behavioral interventions to improve management of HIV and alcohol and on the high rates of risk behaviors in emerging adults (ages...

Active NON-SBIR/STTR RPGS
A wrist biosensor-based mHealth suite to support alcohol intervention in young people living with HIV
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM Florida State University United States 2021 – 2026

ABSTRACT 1 Despite the overall decline in new HIV infections in U.S., adolescents and emerging adults aged 13 to 29 2 remain disproportionately affected by HIV who account for...

Active NON-SBIR/STTR RPGS
Defining intervention targets along pathways from cumulative stress and trauma to alcohol and HIV self-management among young people living with HIV (Project DEFINE)
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM Florida State University United States 2021 – 2026

1 Young people living with HIV (YPLWH) are at high risk for poor HIV self-management, with 2 detectable viral load in 88%, and for hazardous alcohol use which can negatively impa...

Active NON-SBIR/STTR RPGS
Administrative Core: Interventions to improve alcohol-related comorbidities along the gut-brain axis in persons with HIV infection
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM University of Florida United States 2021 – 2026

The Administrative Core is an essential component of the P01 application. The Administrative Core will maintain a central leadership structure and support core resources for the t...

Active NON-SBIR/STTR RPGS
Data Science Core: Interventions to improve alcohol-related comorbidities along the gut-brain axis in persons with HIV infection
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM University of Florida United States 2021 – 2026

The Data Science Core (DSC) will provide critical support for the P01 project as a whole to ensure its success by offering a central source related to research design, data manage...

Active NON-SBIR/STTR RPGS
Novel Extensions of Alcohol Contingency Management in People Living with HIV
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM University of Florida United States 2021 – 2026

PROJECT SUMMARY Alcohol misuse in people living with HIV (PLWH) is a public health issue given relationships to cognitive and physical effects, which may subsequently accelerate...

Active NON-SBIR/STTR RPGS
Cognitive and Inflammation Targeted Gut-Brain Interventions in People Living with HIV who are High-Risk Alcohol Users
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM University of Florida United States 2021 – 2026

RC2 Summary The overarching goal of Research Component 2 (RC2) is to determine whether two non-invasive biological interventions, transcutaneous vagal nerve stimulation (tVNS) a...

Active NON-SBIR/STTR RPGS
Administrative Core
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM Boston Medical Center United States 2021 – 2026

Modified Project Summary/Abstract Section Tuberculosis (TB) is the leading cause of death from a single infectious agent worldwide, and accounts for a third of the total number o...

Active NON-SBIR/STTR RPGS
Biostatistics and Data Management Resource Core
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM Boston Medical Center United States 2021 – 2026

Modified Project Summary/Abstract Section The Biostatistics and Data Management (BDM) Core will play a pivotal role in the International URBAN Alcohol Research Collaboration on H...

Active NON-SBIR/STTR RPGS
The Role of Alcohol Use in Incident TB Infection and Active TB Disease Among Persons Living with HIV
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM Boston Medical Center United States 2021 – 2026

Tuberculosis (TB) is the leading cause of death among persons living with HIV (PLWH); TB disease rates for PLWH engaging in heavy alcohol use are 2-3 times those of alcohol abstai...

Active NON-SBIR/STTR RPGS
The Role of Alcohol Use in Lung Disease After Treatment for Active TB Disease Among Persons Living with HIV
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM Boston Medical Center United States 2021 – 2026

Modified Project Summary/Abstract Section Tuberculosis (TB) is the leading cause of death from a single infectious agent and the leading cause of death in people with HIV (PWH)....