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99,167 grants found
Showing 98,721 – 98,740 of 99,167 grants
SHARE Data Science Core
DATA SCIENCE CORE ABSTRACT Alcohol use that is common among HIV-infected people adversely affects transmission of HIV, engagement and retention in care, and susceptibility to coinf...
Community Engagement Core
PROJECT SUMMARY The translational science spectrum represents each stage of research: pre-clinical, clinical, and implementation science. Conducting research across the translation...
SMARTer Healthy Choices: Optimizing a state-wide scalable intervention to improve alcohol and HIV self-management in adolescents and emerging adults (Project SUSTAIN)
SUSTAIN ABSTRACT Despite decades of research on behavioral interventions to improve management of HIV and alcohol and on the high rates of risk behaviors in emerging adults (ages 1...
A wrist biosensor-based mHealth suite to support alcohol intervention in young people living with HIV
ABSTRACT 1 Despite the overall decline in new HIV infections in U.S., adolescents and emerging adults aged 13 to 29 2 remain disproportionately affected by HIV who account for 37...
Defining intervention targets along pathways from cumulative stress and trauma to alcohol and HIV self-management among young people living with HIV (Project DEFINE)
1 Young people living with HIV (YPLWH) are at high risk for poor HIV self-management, with 2 detectable viral load in 88%, and for hazardous alcohol use which can negatively impac...
Administrative and Clinical Services Core
SUMMARY ABSTRACT The co-directors of the Administrative Core (AC) will be Drs. Nicholas Butowski (UCSF) and Roger Stupp (NU), who will share administrative and clinical responsibil...
Immune Monitoring and Biospecimen Core
PROJECT SUMMARY/ABSTRACT The Immune Monitoring and Biospecimen (IMB) Core is a dedicated to provide the outstanding leadership and expertise in immune monitoring and biospecimen sc...
Leveraging doxorubicin immune-modulation, blood-brain barrier opening, and personalized medicine for effective immunotherapy in glioblastoma. A mechanistic approach and pharmacokinetic trial.
ABSTRACT Despite preclinical promise and occasional long(er) term tumor growth control in subsets of patients, anti-PD1 checkpoint blockade (aPD1) has failed to improve outcome in...
Development of novel synNotch CART cell therapy in adult patients with recurrent EGFRvIII+ glioblastoma
Development of safe and effective (CAR)-transduced T cell (CART) therapy for glioblastoma (GBM) needs to overcome multiple challenges, including on-target off-tumor toxicity, heter...
Microbiome, metabolites, and alcohol in HIV to reduce CVD Cohort (META HIV CVD Cohort)
Unhealthy alcohol use is common in people living with HIV (PLWH) and is associated with cardiovascular disease (CVD) and mortality risk. Prior work suggests that heavy drinking al...
Administration and Data Analytic Core
HARP ADA PROJECT SUMMARY Built on two decades of experience with large coordinated NIAAA-funded research projects on HIV and alcohol, The Veterans Aging Cohort Study (VACS) and o...
Risk Communication Core
HARP RISK COMMUNICATION CORE PROJECT SUMMARY The goal of the HIV and Alcohol Research center focused on Polypharmacy (HARP) is to design and implement effective personalized inte...
Administrative Core
Modified Project Summary/Abstract Section Tuberculosis (TB) is the leading cause of death from a single infectious agent worldwide, and accounts for a third of the total number o...
Cognitive and Inflammation Targeted Gut-Brain Interventions in People Living with HIV who are High-Risk Alcohol Users
RC2 Summary The overarching goal of Research Component 2 (RC2) is to determine whether two non-invasive biological interventions, transcutaneous vagal nerve stimulation (tVNS) a...
A wrist biosensor-based mHealth suite to support alcohol intervention in young people living with HIV
ABSTRACT 1 Despite the overall decline in new HIV infections in U.S., adolescents and emerging adults aged 13 to 29 2 remain disproportionately affected by HIV who account for...
Administrative and Clinical Services Core
SUMMARY ABSTRACT The co-directors of the Administrative Core (AC) will be Drs. Nicholas Butowski (UCSF) and Roger Stupp (NU), who will share administrative and clinical responsib...
Immune Monitoring and Biospecimen Core
PROJECT SUMMARY/ABSTRACT The Immune Monitoring and Biospecimen (IMB) Core is a dedicated to provide the outstanding leadership and expertise in immune monitoring and biospecimen...
Leveraging doxorubicin immune-modulation, blood-brain barrier opening, and personalized medicine for effective immunotherapy in glioblastoma. A mechanistic approach and pharmacokinetic trial.
ABSTRACT Despite preclinical promise and occasional long(er) term tumor growth control in subsets of patients, anti-PD1 checkpoint blockade (aPD1) has failed to improve outcome i...
Development of novel synNotch CART cell therapy in adult patients with recurrent EGFRvIII+ glioblastoma
Development of safe and effective (CAR)-transduced T cell (CART) therapy for glioblastoma (GBM) needs to overcome multiple challenges, including on-target off-tumor toxicity, hete...
CETA-CORE
Project Summary/Abstract Unhealthy alcohol use is a major unaddressed barrier to control of the HIV epidemic in sub-Saharan Africa and the United States. The Zambia Alabama HIV A...