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The Role of Alcohol Use in Incident TB Infection and Active TB Disease Among Persons Living with HIV
Tuberculosis (TB) is the leading cause of death among persons living with HIV (PLWH); TB disease rates for PLWH engaging in heavy alcohol use are 2-3 times those of alcohol abstain...
The Role of Alcohol Use in Lung Disease After Treatment for Active TB Disease Among Persons Living with HIV
ABSTRACT Tuberculosis (TB) is the leading cause of death from a single infectious agent and the leading cause of death in people living with HIV (PLWH). An estimated 8.5 million pe...
Administrative, Education, and Analytic Support Core
Alcohol consumption is an important modifiable cardiovascular disease (CVD) risk factor among people living with HIV infection (PLWH). Given that alcohol use is common among PLWH,...
Integrated Metagenomic and Metabolomic Core
The Integrated Metagenomics and Metabolomics Core (IMMC) will provide a platform that interconnects Projects 1 and 2. Specifically, IMMC will provide high-quality, metagenomics and...
Microbiome, metabolites, and alcohol in HIV to reduce CVD RCT (META HIV CVD RCT)
Among people living with HIV (PLWH), heavy drinking increases the risk of cardiovascular disease (CVD) and death. Data suggest that alcohol-associated gut dysbiosis partially drive...
Microbiome, metabolites, and alcohol in HIV to reduce CVD Cohort (META HIV CVD Cohort)
Unhealthy alcohol use is common in people living with HIV (PLWH) and is associated with cardiovascular disease (CVD) and mortality risk. Prior work suggests that heavy drinking alt...
Administrative Core: Interventions to improve alcohol-related comorbidities along the gut-brain axis in persons with HIV infection
The Administrative Core is an essential component of the P01 application. The Administrative Core will maintain a central leadership structure and support core resources for the tw...
Data Science Core: Interventions to improve alcohol-related comorbidities along the gut-brain axis in persons with HIV infection
The Data Science Core (DSC) will provide critical support for the P01 project as a whole to ensure its success by offering a central source related to research design, data managem...
Novel Extensions of Alcohol Contingency Management in People Living with HIV
PROJECT SUMMARY Alcohol misuse in people living with HIV (PLWH) is a public health issue given relationships to cognitive and physical effects, which may subsequently accelerate HI...
Cognitive and Inflammation Targeted Gut-Brain Interventions in People Living with HIV who are High-Risk Alcohol Users
RC2 Summary The overarching goal of Research Component 2 (RC2) is to determine whether two non-invasive biological interventions, transcutaneous vagal nerve stimulation (tVNS) and...
Alcohol Research Consortium in HIV: Administrative Core
This program project application for the Alcohol Research Consortium on HIV (ARCH)* builds on and extends our very successful administrative and research accomplishments over the p...
Alcohol Research Consortium in HIV: Biostatistics and Method Core
HIV Treatment as Prevention (TASP) is critical to Ending the HIV Epidemic (EHE). At-risk alcohol use and alcohol used disorder (AUD) are barriers to TASP through direct impacts on...
Alcohol Research Consortium in HIV: Epidemiology Research Arm
Unhealthy alcohol use is prevalent among people with HIV (PWH) and associated with poor outcomes including less engagement in the HIV Care Continuum (HIV-CC) and increased age-rela...
Alcohol Research Consortium in HIV: Implementation Research Arm
Despite availability of evidence-based alcohol reduction interventions (EBI), unhealthy alcohol use remains a barrier to HIV medication adherence, viral suppression and retention i...
Alcohol Research Consortium in HIV: Relapse Prevention Arm
At risk alcohol use and alcohol use disorders (AUD) are prevalent among people with HIV (PWH) and cause well-documented harms across the HIV prevention and care continuum. A number...
Administration and Data Analytic Core
HARP ADA PROJECT SUMMARY Built on two decades of experience with large coordinated NIAAA-funded research projects on HIV and alcohol, The Veterans Aging Cohort Study (VACS) and our...
Risk Communication Core
HARP RISK COMMUNICATION CORE PROJECT SUMMARY The goal of the HIV and Alcohol Research center focused on Polypharmacy (HARP) is to design and implement effective personalized interv...
Personalizing Risk from Alcohol among HIV+/-: Genetics, Medication Toxicity and PEth
HARP PROJECT 1 SUMMARY Health risks associated with alcohol use in the context of polypharmacy (AP risks) are likely substantial, particularly for people aging with HIV (PAH). Alco...
Safety and Effectiveness of Medications for Alcohol Use Disorder among HIV+/-
HARP PROJECT 2 SUMMARY Although rarely addressed by HIV healthcare providers, alcohol use disorder (AUD) is a major cause of morbidity and mortality among people aging with HIV (PA...
SHARE Administrative Core
To address research gaps in alcohol and HIV comorbidity in young people living with HIV (YPLWH), particularly in Florida, Florida State University?s SHARE Program (Self-management...