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Showing 97,46197,480 of 99,167 grants

Completed NON-SBIR/STTR RPGS
CORE A - Administrative Core
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Seattle Children'S Hospital United States 2021 – 2025

PROJECT SUMMARY The Administrative Core will coordinate the administrative, fiscal, and organization aspects of our PPG program. Personnel in this Core will facilitate scientific...

Completed NON-SBIR/STTR RPGS
Application of mild therapeutic hypothermia for hearing conservation during cochlear implant surgeries
NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICA... University of Miami School of Medicine United States 2021 – 2025

Project Summary More than half a million patients, including children, have benefitted from the remarkable technological breakthrough that are cochlear implants (CI). An increasing...

$4.2M
USD
Completed NON-SBIR/STTR RPGS
Utilization of Advanced Technologies for the Understanding of Human Structural Birth Defects
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Seattle Children'S Hospital United States 2021 – 2025

PROJECT SUMMARY The unifying theme of this proposal is the aim to use state-of-the-art technologies to investigate the basic biology of mammalian organ development and human struct...

$16.04M
USD
Completed NON-SBIR/STTR RPGS
Incorporation of multilevel ontologies of adverse events and vaccines for vaccine safety surveillance
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Michigan At Ann Arbor United States 2021 – 2025

Incorporation of multilevel ontologies of adverse events and vaccines for vaccine safety surveillance PROJECT SUMMARY Vaccines face tougher safety standards than most pharmaceutic...

$3.75M
USD
Completed NON-SBIR/STTR RPGS
Application of mild therapeutic hypothermia for hearing conservation during cochlear implant surgeries
NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICA... University of Miami School of Medicine United States 2021 – 2025

Project Summary More than half a million patients, including children, have benefitted from the remarkable technological breakthrough that are cochlear implants (CI). An increasi...

$4.05M
USD
Completed NON-SBIR/STTR RPGS
Incorporation of multilevel ontologies of adverse events and vaccines for vaccine safety surveillance
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... William Beaumont Hospital Research Inst United States 2021 – 2025

Incorporation of multilevel ontologies of adverse events and vaccines for vaccine safety surveillance PROJECT SUMMARY Vaccines face tougher safety standards than most pharmaceu...

$2.04M
USD
Completed NON-SBIR/STTR RPGS
Utilization of Advanced Technologies for the Understanding of Human Structural Birth Defects
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Seattle Children'S Hospital United States 2021 – 2025

PROJECT SUMMARY The unifying theme of this proposal is the aim to use state-of-the-art technologies to investigate the basic biology of mammalian organ development and human stru...

$16.04M
USD
Completed NON-SBIR/STTR RPGS
Incorporation of multilevel ontologies of adverse events and vaccines for vaccine safety surveillance
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... William Beaumont Hospital Research Inst United States 2021 – 2025

Incorporation of multilevel ontologies of adverse events and vaccines for vaccine safety surveillance PROJECT SUMMARY Vaccines face tougher safety standards than most pharmaceu...

$3.75M
USD
Completed NON-SBIR/STTR RPGS
Adaptation and optimization of the Friendship Bench mental health intervention for adolescent girls and young women in South African PrEP delivery settings
NATIONAL INSTITUTE OF MENTAL HEALTH University of California, San Francisco United States 2021 – 2025

ABSTRACT The goal of the proposed K99/R00 award is to support Dr. Jennifer Velloza’s development into an independent HIV and mental health researcher, with a focus on improving d...

$2.49M
USD
Completed NON-SBIR/STTR RPGS
Project I - Transcriptomic Analysis of Structural Birth Defects in Mouse Developmental Mutants
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Seattle Children'S Hospital United States 2021 – 2025

PROJECT SUMMARY In this project we plan to apply a powerful and scaleable technique of combinatorial indexing to characterize gene expression at the single-cell level in mice car...

Completed NON-SBIR/STTR RPGS
Project II - 3D Quantitative Analysis of Mouse Models of Structural Birth Defects Through Computational Anatomy
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Seattle Children'S Hospital United States 2021 – 2025

PROJECT SUMMARY E15.5 fetuses of 6 homozygous mutants from each of the 85 sci-RNA-seq lines will be acquired from Project 1 to be imaged via high-resolution microCT following est...

Completed NON-SBIR/STTR RPGS
Project III - Comprehensive Genomic Evaluation of Structural Birth Defects
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Seattle Children'S Hospital United States 2021 – 2025

PROJECT SUMMARY Structural birth defects (SBD) affect 3-6% of live births and are a leading cause of infant morbidity and mortality worldwide. Most SBD are isolated, occur in the...

Completed NON-SBIR/STTR RPGS
Adaptation and optimization of the Friendship Bench mental health intervention for adolescent girls and young women in South African PrEP delivery settings
NATIONAL INSTITUTE OF MENTAL HEALTH University of California, San Francisco United States 2021 – 2025

ABSTRACT The goal of the proposed K99/R00 award is to support Dr. Jennifer Velloza’s development into an independent HIV and mental health researcher, with a focus on improving d...

$2.49M
USD
Completed NON-SBIR/STTR RPGS
CORE A - Administrative Core
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Seattle Children'S Hospital United States 2021 – 2025

PROJECT SUMMARY The Administrative Core will coordinate the administrative, fiscal, and organization aspects of our PPG program. Personnel in this Core will facilitate scientific c...

Completed NON-SBIR/STTR RPGS
Project II - 3D Quantitative Analysis of Mouse Models of Structural Birth Defects Through Computational Anatomy
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Seattle Children'S Hospital United States 2021 – 2025

PROJECT SUMMARY E15.5 fetuses of 6 homozygous mutants from each of the 85 sci-RNA-seq lines will be acquired from Project 1 to be imaged via high-resolution microCT following estab...

Completed NON-SBIR/STTR RPGS
Project III - Comprehensive Genomic Evaluation of Structural Birth Defects
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Seattle Children'S Hospital United States 2021 – 2025

PROJECT SUMMARY Structural birth defects (SBD) affect 3-6% of live births and are a leading cause of infant morbidity and mortality worldwide. Most SBD are isolated, occur in the f...

Completed NON-SBIR/STTR RPGS
Application of mild therapeutic hypothermia for hearing conservation during cochlear implant surgeries
NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICA... University of Miami School of Medicine United States 2021 – 2025

Project Summary More than half a million patients, including children, have benefitted from the remarkable technological breakthrough that are cochlear implants (CI). An increasi...

$4.05M
USD
Completed NON-SBIR/STTR RPGS
Project I - Transcriptomic Analysis of Structural Birth Defects in Mouse Developmental Mutants
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Seattle Children'S Hospital United States 2021 – 2025

PROJECT SUMMARY In this project we plan to apply a powerful and scaleable technique of combinatorial indexing to characterize gene expression at the single-cell level in mice car...

Completed NON-SBIR/STTR RPGS
Project II - 3D Quantitative Analysis of Mouse Models of Structural Birth Defects Through Computational Anatomy
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Seattle Children'S Hospital United States 2021 – 2025

PROJECT SUMMARY E15.5 fetuses of 6 homozygous mutants from each of the 85 sci-RNA-seq lines will be acquired from Project 1 to be imaged via high-resolution microCT following est...

Completed NON-SBIR/STTR RPGS
Project III - Comprehensive Genomic Evaluation of Structural Birth Defects
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Seattle Children'S Hospital United States 2021 – 2025

PROJECT SUMMARY Structural birth defects (SBD) affect 3-6% of live births and are a leading cause of infant morbidity and mortality worldwide. Most SBD are isolated, occur in the...