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Showing 97,08197,100 of 99,167 grants

Completed NON-SBIR/STTR RPGS
Assisted Identification and Navigation of Early Mental Health Symptoms in Children
NATIONAL INSTITUTE OF MENTAL HEALTH Kaiser Foundation Research Institute United States 2021 – 2024

ABSTRACT About 55% of children with significant mental health difficulties receive treatment and up to 80% of children with sub-clinical symptoms receive no treatment. Treatments...

$7.24M
USD
Completed NON-SBIR/STTR RPGS
Care Team and Practice Level Implementation Strategies to Optimize Pediatric Collaborative Care: A Cluster-Randomized Trial
NATIONAL INSTITUTE OF MENTAL HEALTH University of Pittsburgh At Pittsburgh United States 2021 – 2025

PROJECT SUMMARY/ABSTRACT Chronic care models (CCM) that deliver evidence-based practices (EBP) by multidisciplinary provider teams with primary care physicians (PCP) and behavior...

$8.1M
USD
Completed NON-SBIR/STTR RPGS
Intermittent hypoxia and hypertension: Role of the lamina terminalis
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE University of North Texas Hlth Sci Ctr United States 2021 – 2024

The central objective of this research program is to determine the role of the CNS in hypertension associated with chronic intermittent hypoxia (CIH), a model of hypoxemia associa...

$6.8M
USD
Completed NON-SBIR/STTR RPGS
Extracellular Vesicle-Based Digital Scoring Assay for Detecting Early-stage Hepatocellular Carcinoma
NATIONAL CANCER INSTITUTE University of California Los Angeles United States 2021 – 2025

PROJECT SUMMARY Extracellular vesicles (EVs) are a heterogeneous group of phospholipid bilayer-enclosed particles that are released by all types of cells, and even more so by tum...

$6.33M
USD
Completed NON-SBIR/STTR RPGS
Assisted Identification and Navigation of Early Mental Health Symptoms in Children
NATIONAL INSTITUTE OF MENTAL HEALTH Kaiser Foundation Research Institute United States 2021 – 2025

ABSTRACT About 55% of children with significant mental health difficulties receive treatment and up to 80% of children with sub-clinical symptoms receive no treatment. Treatments...

$7.75M
USD
Completed NON-SBIR/STTR RPGS
Extracellular Vesicle-Based Digital Scoring Assay for Detecting Early-stage Hepatocellular Carcinoma
NATIONAL CANCER INSTITUTE University of California Los Angeles United States 2021 – 2025

PROJECT SUMMARY Extracellular vesicles (EVs) are a heterogeneous group of phospholipid bilayer-enclosed particles that are released by all types of cells, and even more so by tum...

$6.13M
USD
Completed NON-SBIR/STTR RPGS
Assisted Identification and Navigation of Early Mental Health Symptoms in Children
NATIONAL INSTITUTE OF MENTAL HEALTH Kaiser Foundation Research Institute United States 2021 – 2024

ABSTRACT About 55% of children with significant mental health difficulties receive treatment and up to 80% of children with sub-clinical symptoms receive no treatment. Treatments a...

$8.11M
USD
Completed NON-SBIR/STTR RPGS
Extracellular Vesicle-Based Digital Scoring Assay for Detecting Early-stage Hepatocellular Carcinoma
NATIONAL CANCER INSTITUTE University of California Los Angeles United States 2021 – 2025

PROJECT SUMMARY Extracellular vesicles (EVs) are a heterogeneous group of phospholipid bilayer-enclosed particles that are released by all types of cells, and even more so by tumor...

$6.6M
USD
Completed NON-SBIR/STTR RPGS
Intermittent hypoxia and hypertension: Role of the lamina terminalis
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE University of North Texas Hlth Sci Ctr United States 2021 – 2024

The central objective of this research program is to determine the role of the CNS in hypertension associated with chronic intermittent hypoxia (CIH), a model of hypoxemia associat...

$6.86M
USD
Completed NON-SBIR/STTR RPGS
High-resolution mapping of the human brainstem during continence and micturition: noninvasive in vivo 7 Tesla fMRI study
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND K... Methodist Hospital Research Institute United States 2021 – 2022

The lower urinary tract (LUT) ? bladder, bladder neck, urethra, and urethral sphincter ? is controlled by a complex neural network. A delicate and complex switch/relay exists betwe...

$1.21M
USD
Completed NON-SBIR/STTR RPGS
Care Team and Practice Level Implementation Strategies to Optimize Pediatric Collaborative Care: A Cluster-Randomized Trial
NATIONAL INSTITUTE OF MENTAL HEALTH University of Pittsburgh At Pittsburgh United States 2021 – 2025

PROJECT SUMMARY/ABSTRACT Chronic care models (CCM) that deliver evidence-based practices (EBP) by multidisciplinary provider teams with primary care physicians (PCP) and behavior...

$7.9M
USD
Completed NON-SBIR/STTR RPGS
Care Team and Practice Level Implementation Strategies to Optimize Pediatric Collaborative Care: A Cluster-Randomized Trial
NATIONAL INSTITUTE OF MENTAL HEALTH University of Pittsburgh At Pittsburgh United States 2021 – 2025

PROJECT SUMMARY/ABSTRACT Chronic care models (CCM) that deliver evidence-based practices (EBP) by multidisciplinary provider teams with primary care physicians (PCP) and behavior...

$8.1M
USD
Completed NON-SBIR/STTR RPGS
Intermittent hypoxia and hypertension: Role of the lamina terminalis
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE University of North Texas Hlth Sci Ctr United States 2021 – 2025

The central objective of this research program is to determine the role of the CNS in hypertension associated with chronic intermittent hypoxia (CIH), a model of hypoxemia associa...

$6.67M
USD
Completed NON-SBIR/STTR RPGS
Care Team and Practice Level Implementation Strategies to Optimize Pediatric Collaborative Care: A Cluster-Randomized Trial
NATIONAL INSTITUTE OF MENTAL HEALTH University of Pittsburgh At Pittsburgh United States 2021 – 2025

PROJECT SUMMARY/ABSTRACT Chronic care models (CCM) that deliver evidence-based practices (EBP) by multidisciplinary provider teams with primary care physicians (PCP) and behavioral...

$8.38M
USD
Completed NON-SBIR/STTR RPGS
TGF-b superfamily signaling in controlling Th17 cell function in autoimmune neuroinflammation
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of North Carolina Chapel Hill United States 2021 – 2025

Project Summary: Multiple sclerosis (MS) is a debilitating autoimmune neuroinflammation disease inflicting millions of people worldwide. It is caused by dysregulated adaptive an...

$3.83M
USD
Completed NON-SBIR/STTR RPGS
TGF-b superfamily signaling in controlling Th17 cell function in autoimmune neuroinflammation
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of North Carolina Chapel Hill United States 2021 – 2025

Project Summary: Multiple sclerosis (MS) is a debilitating autoimmune neuroinflammation disease inflicting millions of people worldwide. It is caused by dysregulated adaptive an...

$3.83M
USD
Completed NON-SBIR/STTR RPGS
TGF-b superfamily signaling in controlling Th17 cell function in autoimmune neuroinflammation
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of North Carolina Chapel Hill United States 2021 – 2025

Project Summary: Multiple sclerosis (MS) is a debilitating autoimmune neuroinflammation disease inflicting millions of people worldwide. It is caused by dysregulated adaptive an...

$3.83M
USD
Completed NON-SBIR/STTR RPGS
TGF-b superfamily signaling in controlling Th17 cell function in autoimmune neuroinflammation
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of North Carolina Chapel Hill United States 2021 – 2025

Project Summary: Multiple sclerosis (MS) is a debilitating autoimmune neuroinflammation disease inflicting millions of people worldwide. It is caused by dysregulated adaptive and...

$3.83M
USD
Completed NON-SBIR/STTR RPGS
The impact of post acute care payment changes on access and outcomes
NATIONAL INSTITUTE ON AGING University of Pittsburgh At Pittsburgh United States 2021 – 2024

Project Summary/Abstract Substantial changes in Medicare payment policies are occurring for post-acute care (PAC), which provides a bridge from the hospital to home for individuals...

$7.71M
USD
Completed NON-SBIR/STTR RPGS
Adaptive optical microscopy for high-accuracy recording of neural activity in vivo
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND S... University of California Berkeley United States 2021 – 2023

PROJECT SUMMARY To understand the computations in the brain, we need to monitor the activity of neural circuits at high accuracy, which requires methodologies with high spatial and...

$5.77M
USD