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Showing 95,98196,000 of 99,167 grants

Completed NON-SBIR/STTR RPGS
Epidemiology and Impact of the HIV, NCD, and Urbanization Syndemic in Africa
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Johns Hopkins University United States 2021 – 2026

Africa bears the vast majority (69%) of the world?s current HIV infections with 26 million persons living with HIV (PLHIV).Increased access to antiretroviral therapy (ART) in Afric...

$15.67M
USD
Completed NON-SBIR/STTR RPGS
IL-27-producing B cells in the antibody response
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Texas Hlth Science Center United States 2021 – 2026

PROJECT SUMMARY ?IL-27-producing B cells in the antibody response Built on our novel findings that B cells can be induced to express high levels of IL-27 (IL27p28/EBI3 heterodimer)...

$4.43M
USD
Completed NON-SBIR/STTR RPGS
T-cell Dysfunction as the basis of Disseminated Coccidioidomycosis
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of California Los Angeles United States 2021 – 2023

PROJECT SUMMARY/ABSTRACT Disseminated coccidioidomycosis (DCM) is an uncommon but life-threatening consequence of infection by the fungus Coccidioides. Why some people get DCM and...

$1.98M
USD
Completed NON-SBIR/STTR RPGS
Microbiome Impact on the Susceptibility and Severity to Cryptosporidium Infection
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Emory University United States 2021 – 2023

Cryptosporidium spp. are opportunistic protozoan parasites that infect epithelial cells of the small intestine, causing diarrheal illness in humans. In immunodeficient individuals,...

$2.34M
USD
Completed NON-SBIR/STTR RPGS
Epigenetic and Metabolic Regulation of Gene Silencing in Saccharomyces
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES University of California Berkeley United States 2021 – 2026

This application for a MIRA award seeks to consolidate the research in the PI's lab, funded by GM31105 Genetic Analysis of Genes Controlling a Position Effect, currently in it...

$9.95M
USD
Completed NON-SBIR/STTR RPGS
The impact of enculturation on the epigenetic relationship between chronic stress and hypertension in Yup'ik Alaska Native people
NATIONAL INSTITUTE ON MINORITY HEALTH AND HEALTH D... Oregon Health & Science University United States 2021 – 2025

Project Summary The objective of the proposed research is to identify molecular mechanisms linking the protective role of culture to blood pressure regulation, a major risk factor...

$6.96M
USD
Completed NON-SBIR/STTR RPGS
Dietary influence on infant growth and the gut microbiota
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND K... University of Colorado Denver United States 2021 – 2026

The overall objective of this project is to establish how infant diet with different protein-rich foods regulate growth trajectories and gut microbiota development.Both NIH and USD...

$6.67M
USD
Completed NON-SBIR/STTR RPGS
The interplay of ion transporters and cytoskeleton in breast cancer migration and metastasis
NATIONAL CANCER INSTITUTE Johns Hopkins University United States 2021 – 2026

The inability to clinically treat tumor metastasis is responsible for the majority of cancer patient deaths. Cell migration is a pivotal step in the metastatic dissemination of can...

$4.87M
USD
Completed NON-SBIR/STTR RPGS
Epidemiology and Impact of the HIV, NCD, and Urbanization Syndemic in Africa
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Johns Hopkins University United States 2021 – 2026

Africa bears the vast majority (69%) of the world’s current HIV infections with 26 million persons living with HIV (PLHIV). Increased access to antiretroviral therapy (ART) in Afri...

$15.99M
USD
Completed NON-SBIR/STTR RPGS
T-cell Dysfunction as the basis of Disseminated Coccidioidomycosis
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of California Los Angeles United States 2021 – 2024

PROJECT SUMMARY/ABSTRACT Disseminated coccidioidomycosis (DCM) is an uncommon but life-threatening consequence of infection by the fungus Coccidioides. Why some people get DCM and...

$2.23M
USD
Completed NON-SBIR/STTR RPGS
IL-27-producing B cells in the antibody response
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Texas Hlth Science Center United States 2021 – 2026

PROJECT SUMMARY – IL-27-producing B cells in the antibody response Built on our novel findings that B cells can be induced to express high levels of IL-27 (IL27p28/EBI3 heterodimer...

$4.45M
USD
Completed NON-SBIR/STTR RPGS
Microbiome Impact on the Susceptibility and Severity to Cryptosporidium Infection
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Emory University United States 2021 – 2023

Cryptosporidium spp. are opportunistic protozoan parasites that infect epithelial cells of the small intestine, causing diarrheal illness in humans. In immunodeficient individuals,...

$1.96M
USD
Completed NON-SBIR/STTR RPGS
The interplay of ion transporters and cytoskeleton in breast cancer migration and metastasis
NATIONAL CANCER INSTITUTE Johns Hopkins University United States 2021 – 2026

The inability to clinically treat tumor metastasis is responsible for the majority of cancer patient deaths. Cell migration is a pivotal step in the metastatic dissemination of can...

$776.4K
USD
Completed NON-SBIR/STTR RPGS
Dietary influence on infant growth and the gut microbiota
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND K... University of Colorado Denver United States 2021 – 2026

The overall objective of this project is to establish how infant diet with different protein-rich foods regulate growth trajectories and gut microbiota development.Both NIH and USD...

$1.56M
USD
Completed NON-SBIR/STTR RPGS
Epidemiology and Impact of the HIV, NCD, and Urbanization Syndemic in Africa
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Johns Hopkins University United States 2021 – 2026

Africa bears the vast majority (69%) of the world’s current HIV infections with 26 million persons living with HIV (PLHIV). Increased access to antiretroviral therapy (ART) in Afri...

$15.67M
USD
Completed NON-SBIR/STTR RPGS
The impact of enculturation on the epigenetic relationship between chronic stress and hypertension in Yup'ik Alaska Native people
NATIONAL INSTITUTE ON MINORITY HEALTH AND HEALTH D... Oregon Health & Science University United States 2021 – 2025

Project Summary The objective of the proposed research is to identify molecular mechanisms linking the protective role of culture to blood pressure regulation, a major risk factor...

$3.86M
USD
Completed NON-SBIR/STTR RPGS
IL-27-producing B cells in the antibody response
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Texas Hlth Science Center United States 2021 – 2026

PROJECT SUMMARY – IL-27-producing B cells in the antibody response Built on our novel findings that B cells can be induced to express high levels of IL-27 (IL27p28/EBI3 heterodimer...

$4.45M
USD
Completed NON-SBIR/STTR RPGS
Dietary influence on infant growth and the gut microbiota
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND K... University of Colorado Denver United States 2021 – 2026

The overall objective of this project is to establish how infant diet with different protein-rich foods regulate growth trajectories and gut microbiota development.Both NIH and USD...

$6.57M
USD
Completed NON-SBIR/STTR RPGS
Epigenetic and Metabolic Regulation of Gene Silencing in Saccharomyces
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES University of California Berkeley United States 2021 – 2024

This application for a MIRA award seeks to consolidate the research in the PI's lab, funded by GM31105 Genetic Analysis of Genes Controlling a Position Effect, currently in it...

$1.95M
USD
Completed NON-SBIR/STTR RPGS
The interplay of ion transporters and cytoskeleton in breast cancer migration and metastasis
NATIONAL CANCER INSTITUTE Johns Hopkins University United States 2021 – 2026

The inability to clinically treat tumor metastasis is responsible for the majority of cancer patient deaths. Cell migration is a pivotal step in the metastatic dissemination of can...

$4.82M
USD