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Showing 921940 of 99,167 grants

Active NON-SBIR/STTR RPGS
Understanding Integration in Oncology Care and Association with Quality and Outcomes
NATIONAL CANCER INSTITUTE Harvard Medical School United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT: Overall Program Project This Program Project seeks to understand features of care integration in oncology that are associated with higher-quality care del...

$22.83M
USD
Active NON-SBIR/STTR RPGS
Administrative Core
NATIONAL CANCER INSTITUTE Harvard Medical School United States 2024 – 2029

ADMINISTRATIVE CORE PROJECT SUMMARY/ABSTRACT The Administrative Core provides coordination and administrative oversight for the Program Project, “Understanding Integration in Oncol...

Active NON-SBIR/STTR RPGS
Project 1: Care Integration for Patients with Cancer Treated in Health Systems
NATIONAL CANCER INSTITUTE Harvard Medical School United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT: Project 1 - Care Integration for Patients with Cancer Treated in Health Systems This Project focuses on care integration for patients with cancer who are...

Active NON-SBIR/STTR RPGS
Project 2: Care Integration for Patients with Cancer Treated in Independent Practices
NATIONAL CANCER INSTITUTE Harvard Medical School United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT: Project 2 - Care Integration for Patients with Cancer Treated in Independent Practices The goal of this Project is to describe care integration for patien...

Active NON-SBIR/STTR RPGS
Project 3: Care Integration for Patients with Cancer Receiving Post-Acute Care and Hospice
NATIONAL CANCER INSTITUTE Harvard Medical School United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT: Project 3 - Care Integration for Patients Receiving Post-Acute Care and Hospice This Project focuses on care integration for patients with cancer who are...

Active NON-SBIR/STTR RPGS
Project 4: Care Integration for Patients with Cancer Using Specialty Pharmacies
NATIONAL CANCER INSTITUTE Harvard Medical School United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT: Project 4 - Care Integration for Patients with Cancer Using Specialty Pharmacies This project aims to examine the integration of specialty pharmacies into...

Active NON-SBIR/STTR RPGS
Statistical Methods and Data Core
NATIONAL CANCER INSTITUTE Harvard Medical School United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT: Statistical Methods and Data Core The Statistical Methods and Data Core will provide technical expertise in data and analysis and develop new methods to d...

Active NON-SBIR/STTR RPGS
Sensor-Like LC-MS Platform for Rapid Online Monitoring of Metabolites in Biological Systems
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES Rowan University United States 2024 – 2029

Project Summary Our research program focuses on the development of analytical tools to enhance the characterization of complex biological systems. For rapid, real-time analysis of...

$3.75M
USD
Active NON-SBIR/STTR RPGS
Great apes and the evolutionary origins of long life: the influences of early life adversity on lifespan and individual frailty in wild chimpanzees and gorillas
NATIONAL INSTITUTE ON AGING Dian Fossey Gorilla Fund I United States 2024 – 2029

PROJECT SUMMARY While one of the most remarkable features of the human species is our capacity for extreme longevity, understanding the marked variation in life spans within and be...

$7.87M
USD
Active NON-SBIR/STTR RPGS
Elucidating chronic liver disease pathways using somatic genetics
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND K... Ut Southwestern Medical Center United States 2024 – 2029

PROJECT SUMMARY Chronic liver disease is common and its pathogenic mechanisms are complex. There are no high throughput genetic methods to uncover mechanisms that drive progression...

$7.54M
USD
Active NON-SBIR/STTR RPGS
Development of large-scale composite null hypothesis testing approaches to perform translational genetics analyses
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES University of Tx Md Anderson Can Ctr United States 2024 – 2029

Abstract/Project Summary Germline genetics research often relies heavily on large-scale hypothesis testing to detect associations between complex traits and their risk mutations. T...

$4.09M
USD
Active NON-SBIR/STTR RPGS
Accelerating Behavioral and Social Sciences through Ontology Development and Application: NIH Research Network Project (APRICOT).
NATIONAL CANCER INSTITUTE University College London United Kingdom 2024 – 2029

Title: Advancing Prevention Research In Cancer through Ontology Tools (The APRICOT project) Abstract Progress in behavioral research in cancer prevention is hampered by imprecision...

$5.01M
USD
Active NON-SBIR/STTR RPGS
Chemical proteomic mapping and functional manipulation of extracellular proteinaceous cysteines
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES Northwestern University United States 2024 – 2029

Project Summary Around 262,000 cysteine residues are intricately distributed throughout the human proteome. These cysteinesplay pivotal roles in influencing protein folding, stabil...

$3.9M
USD
Active NON-SBIR/STTR RPGS
A reproducible database for untargeted metabolomics data processing across laboratories
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES University of California At Davis United States 2024 – 2028

Project Summary Scientific teams led by Prof. Oliver Fiehn (UC Davis), Prof. Charles Evans (University of Michigan) and Dr. Tom Metz (Pacific Northwest National Laboratory) will de...

$5.33M
USD
Active NON-SBIR/STTR RPGS
Treatment of Health Complications due to Female Genital Mutilation/Cutting in Tanzania: Curriculum Build, Implementation, and Evaluation
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... University of Minnesota United States 2024 – 2029

ABSTRACT Female genital mutilation/cutting (FGM/C) affects girls and women throughout the world, with 3 million girls cut each year. The highest rates of FGM/C are in East Africa....

$6.09M
USD
Active NON-SBIR/STTR RPGS
Genes, neighborhoods, and alcohol misuse from adolescence to mid-adulthood in the Add Health study
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM University of Wisconsin-Madison United States 2024 – 2027

PROJECT SUMMARY Where one lives is an important contributor to disparities in health behaviors and outcomes, but it has been difficult to draw firm conclusions on the relations bet...

$3.15M
USD
Active NON-SBIR/STTR RPGS
Computational Framework for the Mechanistic Studies and Physics-Informed Prediction and Design of Photoenzymes
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES Northeastern University United States 2024 – 2029

A robust enzyme design strategy will profoundly impact human health, such as by achieving asymmetric synthesis of pharmaceuticals not easy to be achieved by small-molecule catalyst...

$4M
USD
Active NON-SBIR/STTR RPGS
Developing Switchable and Functional Fluorophores For Multi-Functional Super-Resolution Microscopy
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES North Carolina State University Raleigh United States 2024 – 2029

Project Summary The overarching goal of the PI’s research program is to decode the intricate biophysical and biochemical functions in diverse molecular processes underlined by the...

$3.65M
USD
Active NON-SBIR/STTR RPGS
Observational causal inference with infectious disease outcomes
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES Brown University United States 2024 – 2029

Project Summary Infectious disease is a leading cause of global morbidity and mortality. Transmission dynamic models have played a critical role in guiding interventions related to...

$3.83M
USD
Active NON-SBIR/STTR RPGS
The Effects of Changing Health Care Markets on Cardiovascular and Cerebrovascular Care and Outcomes
NATIONAL INSTITUTE ON AGING Massachusetts General Hospital United States 2024 – 2029

PROJECT SUMMARY The health care delivery system is undergoing tremendous changes, with increasing consolidation from mergers and acquisitions, as well as openings and closings of h...

$7.75M
USD