Browse All Grants
99,167 grants found
Showing 4,241 – 4,260 of 99,167 grants
Impact of ableism and state laws designed to mitigate ableism on organ transplant equity for kidney transplant candidates with intellectual or developmental disabilities
PROJECT SUMMARY Ableist discrimination is pervasive in healthcare and negatively affects the US organ transplant system, resulting in patients with intellectual or developmental di...
Hydrogel-based lymphoid tissues for generation of activated human B cells and delivery in vivo
Research Summary Humoral immunity against infections requires the germinal center (GC) differentiation process in the B cell follicles of lymph nodes. In GCs, naïve B cells rapidly...
Identifying and Measuring Domains of Structural Ableism to Advance Health Equity for the Disability Community
ABSTRACT Structural ableism, defined as the processes, policies, and institutions that privilege able-bodied people over disabled people, is a root cause of health inequities faced...
Identifying the impact of ableism on maternal health outcomes among Medicaid-enrolled women with IDD
PROJECT ABSTRACT The proposed study will conduct a detailed examination of the impact of ableism on women with intellectual and developmental disabilities (I/DD) during pregnancy a...
Biological Basis of Genetic cMyBP-C Cardiomyopathies
ABSTRACT This collaborative project integrates fundamental molecular biology, cell level biophysics, animal-level physiology, and computer modeling to advance understanding of mole...
A Systematic Toolkit for Counteracting HIV Drug Resistance with Protein Structural Dynamics
Project Summary HIV-1 presents a severe global health challenge. Due to the high genetic variability of HIV and the lifelong duration of the standard treatment, resistant mutations...
Biomechanical treatment of carpal tunnel syndrome for Hispanic women
Abstract Carpal tunnel syndrome is the most common compressive neuropathy. The need for advancement in therapeutic treatment modalities is evidenced by the disease prevalence, pote...
Role of HIV-1 integrase in virion morphogenesis and its targeting by allosteric integrase inhibitors
Abstract New therapeutic options are needed to treat people infected with multi-drug resistant HIV-1 phenotypes. Here we propose to both investigate and exploit the non-catalytic,...
Modulation of Galectin-9 to Target HIV Persistence
PROJECT SUMMARY While the advent of antiretroviral therapy (ART) has dramatically reduced the morbidity and mortality associated with HIV infection, viral eradication is not achiev...
Nonsense-mediated mRNA decay and beyond
This MIRA application extends our decades-long research on nonsense-mediated mRNA decay (NMD) and how NMD factors can function in other aspects of cellular metabolism. NMD is a fun...
IP24-045, SEAPREP: Seattle Pandemic Preparedness Cohort
ABSTRACT Community-based surveillance studies of respiratory viruses provide the opportunity for early viral detection and situational awareness, and may inform early public health...
IP24-045, A Prospective Observational Study of Respiratory Virus Epidemiology in the Greater Boston Area
PROJECT SUMMARY/ABSTRACT Despite the extensive epidemiologic research conducted during the COVID-19 pandemic, there remain gaps in our knowledge about the epidemiology and transmis...
IP24-045, PREVENT: Preparedness through Respiratory Virus Epidemiology and Community Engagement
SUMMARY Monitoring of the incidence, morbidity, and mortality of respiratory infections has largely been performed by collecting and analyzing data from hospitals and clinical labo...
Improving Participation in Pulmonary Rehabilitation through Peer-Support and Storytelling
ABSTRACT Exacerbations of Chronic Obstructive Pulmonary Disease (COPD) lead to roughly 1.5 million ED visits and 700,000 hospitalizations annually. Recovery is slow, and accompanie...
Mixed Methods Supplement for the MOLAR study
Project Abstract The MOLAR study uses a hybrid effectiveness-implementation study to perform a randomized controlled trial of an intervention to reduce unmet oral health and social...
Nitrosamines Forum to Advance Critical Translational Science (NA FACTS)
Title: Nitrosamines Forum for Advancing Critical Translational Science (NA FACTS) FOA Title & Number: Identification and Evaluation of Possible Approaches to Addressing Nitrosa...
Identifying and addressing barriers to clinical trial participation of Urban American Indians by creating a community research worker role
Project Summary This project seeks to advance equity in clinical trials by identifying and addressing barriers to clinical trial participation experienced by urban American Indians...
Expanding the Public Awareness of Skin-lightening Practices and Chemical Exposure and Creating a Framework that Advances the Wellbeing of Impacted Communities
Project Summary Project activities: Communities receive information in diverse formats-- from trusted community health workers, cultural brokers, local language media, and communit...
Building Hybrid Operations to Promote Equity (HOPE) and improve clinical trial access across North Carolina
ABSTRACT The landscape of clinical research is in a constant state of evolution as a greater understanding of unmet patient needs and current clinical trial limitations are exposed...
Advancing Health Equity Through Linguistic Inclusion in Clinical Trials
Project Summary/Abstract The proposed effort is focused on integrating community voices into existing organizational efforts to advance linguistic inclusion in clinical research. C...