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99,167 grants found
Showing 241 – 260 of 99,167 grants
BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy
Summary Current HIV curative strategies have proven insufficient to eradicate viral reservoirs or prevent viral rebound after antiretroviral therapy (ART) cessation. The unifying...
Wisconsin Registry for Alzheimer's Prevention
PROJECT SUMMARY The Wisconsin Registry for Alzheimer’s Prevention (WRAP) is a longitudinal study that follows a risk-enriched cohort from late-midlife into old age and focuses on...
B and T Cell Biology of Protection from and Eradication of SIV/SHIV Infection
ABSTRACT The Emory Consortium for Innovative HIV/AIDS Vaccine and Cure Research in Nonhuman Primates aims to define the mechanisms of the B and T Cell Biology of Protection from...
New Horizons in the Prevention and Treatment of Food Allergy
Project Summary: Food allergy affects approximately 5-10% of young children, with highest incidence in the first year of life. Food allergy accounts for almost $25 billion per ye...
Plasma brain-derived tau: a novel Alzheimer’s disease-type neurodegeneration biomarker with potential to complete the AT(N) scheme in blood
While the Amyloid(A)/Tau(T)/Neurodegeneration(N) framework has been validated against neuropathology, cerebrospinal fluid (CSF) and neuroimaging biomarkers, its implementation in...
BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy
Summary Current HIV curative strategies have proven insufficient to eradicate viral reservoirs or prevent viral rebound after antiretroviral therapy (ART) cessation. The unifying...
Study of Latinos-Investigation of Neurocognitive Aging-Alzheimer's disease
Abstract By 2060, the CDC projects that the Latino population will experience the largest increase in Alzheimer’s disease and related dementia (ADRD) cases of all US ethnic/racia...
National Longitudinal Study of Adolescent to Adult Health (Add Health): Wave VI Core Project
Project Summary This project, developed in response to RFA-AG-21-008, describes core plans for data collection and dissemination of the sixth wave (Wave VI) of the National Longi...
IP24-045, PREVENT: Preparedness through Respiratory Virus Epidemiology and Community Engagement
SUMMARY Monitoring of the incidence, morbidity, and mortality of respiratory infections has largely been performed by collecting and analyzing data from hospitals and clinical la...
National Longitudinal Study of Adolescent to Adult Health (Add Health): Wave VI Cognition and Early Risk Factors for Dementia Project
Project Summary Alzheimer's Disease and Related Dementias (ADRD) are projected to affect 14 million Americans by 2050. To date, though, research on the signs and symptoms of ADRD...
BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy
Summary Current HIV curative strategies have proven insufficient to eradicate viral reservoirs or prevent viral rebound after antiretroviral therapy (ART) cessation. The unifying...
Neural Architecture of the Murine and Human Temporomandibular Joint
ABSTRACT: Temporomandibular disorders (TMDs) are the most common form of chronic orofacial pain, affecting 5% of U.S. adults. Despite substantial clinical and research interest i...
SOSIP-NP/mRNA combination for novel preventive and therapeutic HIV-1 vaccine regimens
ABSTRACT The ultimate goal of the proposed studies is to contribute to ending the HIV/AIDS epidemic. It has been four decades since the start of the HIV/AIDS epidemic and a prot...
Pediatric Adolescent Virus Elimination (PAVE) Martin Delaney Collaboratory
ABSTRACT The immediate establishment of the latent HIV-1 reservoir in resting memory CD4+ T cells precludes HIV-1 cure, compelling ART for a lifetime in children. The mission of th...
SOSIP-NP/mRNA combination for novel preventive and therapeutic HIV-1 vaccine regimens
ABSTRACT The ultimate goal of the proposed studies is to contribute to ending the HIV/AIDS epidemic. It has been four decades since the start of the HIV/AIDS epidemic and a prot...
Consortium for Translational and Precision Health
The Consortium for Translational and Precision Health (CTPH) will serve as a unique bi-institutional hub for infrastructure, services, community engagement, and workforce developm...
Center for Clinical and Translational Sciences
PROJECT SUMMARY/ ABSTRACT Since its inception in 2006, our CCTS has assembled a well-integrated, and high-impact network in Texas including 6 academic institutions: The Universit...
NJ ACTS: A Platform for Translational Science in New Jersey
Abstract: After 4 years, the New Jersey Alliance for Clinical and Translational Science (NJ ACTS), a partnership among four institutions, Rutgers, Princeton Universities, the New...
Plasma brain-derived tau: a novel Alzheimer’s disease-type neurodegeneration biomarker with potential to complete the AT(N) scheme in blood
While the Amyloid(A)/Tau(T)/Neurodegeneration(N) framework has been validated against neuropathology, cerebrospinal fluid (CSF) and neuroimaging biomarkers, its implementation in...
REACH: Research Enterprise to Advance a Cure for HIV
PROJECT SUMMARY/ABSTRACT Despite the success of standard antiretroviral therapy (ART), the need for an HIV cure remains compelling, both to improve the lives of PWH and to bring ab...