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active discretionary Grants.gov

Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R21 Clinical Trial Not Allowed)

$861K USD

Funder National Institutes of Health
Recipient Organization Not specified
Country USA
Start Date Nov 18, 2024
End Date Jan 10, 2027
Duration 783 days
Number of Grantees 1
Data Source Grants.gov
Grant ID f4d5f64e-0b81-4634-b3c1-9993ef53c00c
Grant Description

The goal of the proposed funding announcement is twofold, to promote preclinical and patient based studies examining the mechanism(s) through which incretin mimetics (including agonists or antagonists of GLP-1, GIP-1, or dual GLP-1/GIP-1 agents) impact cancer risk, and to draw talented scientists who understand the dynamic changes caused by these agents to investigate the mechanisms of how these agents influence cancer risk rather than shorter term outcomes such as weight loss and diabetes.

The data thus far suggests that these agents may increase the risk of some, while decreasing the risk of other obesity related cancers.

All Grantees

To be determined

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