Pediatric Phase I/II age de-escalation dose finding study of a vaccine against invasive non-typhoidal salmonellosis in sub-Saharan Africa (PEDVAC-iNTS)

€569.9K EUR

Funder	European & Developing Countries Clinical Trials Partnership (EDCTP)
Recipient Organization	Sclavo Vaccines Association (Sva)
Country	Based in EU
Start Date	Mar 01, 2021
End Date	Feb 28, 2025
Duration	1,460 days
Number of Grantees	1
Roles	Award Holder
Data Source	Europe PMC
Grant ID	`RIA2019AMR-2658`

Grant Description

Invasive non-typhoidal salmonellosis (iNTS), an important overlooked poverty-related infectious disease in sub- Saharan Africa (sSA), is associated with increasing antibiotic resistance (AMR) and is classified by the World Health Organization as a high priority pathogen for developing new antibiotics.

Despite an estimated 59,100 iNTS deaths in 2017 and 14.5% case fatality rate particularly in children