A novel technology for long-term mapping of memory representations in the brain

Memories are highly dynamic and can be updated, forgotten or transformed with the passing of time. In the brain, memories are represented by alterations in the connections between activated neurons.

The investigation of these time-dependent changes in memories at the level of their neural representation therefore requires long-term mapping of neuronal connectivity. So far this was not possible.

This project will develop a new technique to capture the neuronal connectivity footprints of specific memories in the brain, enabling the investigation of the dynamic nature of memory representations over time.