Definitively characterise DNA damage in complex DNA structures, from supercoiled DNA to replication intermediates. 2. Determine how binding of key DNA

Funder	Medical Research Council
Recipient Organization	University of Sheffield
Country	United Kingdom
Start Date	Sep 30, 2024
End Date	Sep 29, 2028
Duration	1,460 days
Number of Grantees	2
Roles	Student; Supervisor
Data Source	UKRI Gateway to Research
Grant ID	`2927989`

Grant Description

Definitively characterise DNA damage in complex DNA structures, from supercoiled DNA to replication intermediates. 2. Determine how binding of key DNA repair factors (e.g. PARP) alter the structure of damaged DNA molecules.