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Completed DISCRETIONARY AWARD - MENTAL HEALTH Europe PMC

Can we develop a "cognitive vaccine" for intrusive memories of traumatic events from working in the COVID-19 pandemic? A novel and brief intervention to support ICU staff

£9.11M GBP

Funder Wellcome Trust
Recipient Organization University of Uppsala
Country United Kingdom
Start Date May 04, 2021
End Date Dec 03, 2023
Duration 943 days
Number of Grantees 1
Roles Award Holder
Data Source Europe PMC
Grant ID 223016
Grant Description

Intensive care unit (ICU) staff face repeated exposure to traumatic work-related events and have reported high levels of posttraumatic symptoms during the pandemic. Novel, scalable and preventative interventions are required.

We are developing a “cognitive vaccine” approach for ICU staff against one key symptom – intrusive memories of traumatic events. These are unwanted, distressing and disrupt functioning.

Our novel, brief gameplay intervention is repeatable, flexible, non-stigmatising, scalable, and driven by mental health science.

This digital intervention is guided by an initial session of psychologist support, then self-administered; delivered same day or months post-trauma, suitable for repeated trauma exposure, fits with busy lives of ICU staff, without discussing trauma detail.

Part 1 uses a Bayesian design to optimise and co-develop procedures with ICU professionals and move at speed under pandemic conditions, allowing limited rollout (guided-version) in these unprecedented times.

Part 2 uses a pragmatic RCT (three arms: guided/non-guided/attention-control) testing clinical effectiveness and acceptability to inform clinical practice. If the non-guided intervention is effective (i.e. no psychologist support) it will accelerate the speed of rollout.

Meanwhile through global mental health workshops with stakeholder communities we seek to understand the views of various communities worldwide regarding implementation of this novel intervention form.

All Grantees

University of Uppsala

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