Antibiotic-free, stimuli-responsive hybrid electrospun wound dressings

The project aims to create antibiotic-free, stimuli-responsive wound dressings that can disinfect chronic wounds without promoting antimicrobial resistant bacteria.

This will be achieved by ngineering nanoparticles that respond to external stimuli and incorporating them into precision polymers to create wound dressings.

The dressings will disinfect chronic wounds on-demand, reducing the need for antibiotics and minimizing the emergence of antimicrobial resistant strains.

The project combines expertise from three research groups that will work together to develop the next generation of stimuli-responsive nanoparticles and blend them inside functional polymers prior to their electrospinning into fibrous wound dressings.

The ultimate goal is to transform current clinical practices into precision treatments, enhancing therapeutic outcomes for patients with chronic wounds and reducing medical costs.

Our nanoengineering approach will provide fundamental insight into physicochemical properties that dictate the precise use of nanomaterials in the chronic wound microenvironment.

The outcome of this research will support precision treatments improving the quality of life of patients with chronic wounds.